Search Results - "Nott, J."

Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles by Nott, Timothy J., Petsalaki, Evangelia, Farber, Patrick, Jervis, Dylan, Fussner, Eden, Plochowietz, Anne, Craggs, Timothy D., Bazett-Jones, David P., Pawson, Tony, Forman-Kay, Julie D., Baldwin, Andrew J.

“…Cells chemically isolate molecules in compartments to both facilitate and regulate their interactions. In addition to membrane-encapsulated compartments, cells…”
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Structural and hydrodynamic properties of an intrinsically disordered region of a germ cell-specific protein on phase separation by Brady, Jacob P., Farber, Patrick J., Sekhar, Ashok, Lin, Yi-Hsuan, Huang, Rui, Bah, Alaji, Nott, Timothy J., Chan, Hue Sun, Baldwin, Andrew J., Forman-Kay, Julie D., Kay, Lewis E.

“…Membrane encapsulation is frequently used by the cell to sequester biomolecules and compartmentalize their function. Cells also concentrate molecules into…”
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Deciphering arginine methylation: Tudor tells the tale by Chen, Chen, Pawson, Tony, Nott, Timothy J, Jin, Jing

“…Key Points The royal superfamily domains, which include Tudor, chromo, MBT, PWWP and agenet domains, read protein methylation. The Tudor protein family…”
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Multiple cranial nerve motor deficits, resembling polyneuritis cranialis, in a cat with hyperthyroidism by Holland, CT, Nott, JK

“…A 14 plus‐year‐old (exact age unknown) neutered female domestic shorthair cat presented with a 6‐day history of rapidly evolving difficulty in eating, dropped…”
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Membraneless organelles can melt nucleic acid duplexes and act as biomolecular filters by Nott, Timothy J., Craggs, Timothy D., Baldwin, Andrew J.

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Improving the Accuracy of Marginal Approximations in Likelihood-Free Inference via Localization by Drovandi, Christopher, Nott, David J., Frazier, David T.

“…Likelihood-free methods are an essential tool for performing inference for implicit models which can be simulated from, but for which the corresponding…”
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Putting the Cart Before the Horse? Developing a Blended Anatomy Curriculum Supplemented by Cadaveric Anatomy by Donald, E, Dulohery, K, Khamuani, M, Miles, H, Nott, J, Patten, D, Roberts, A

“…Cadaveric anatomy is frequently described as the gold standard for anatomy education. Increasingly and especially following the COVID-19 pandemic, there is…”
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The Impact of Sampling Strategy on the Cloud Droplet Number Concentration Estimated From Satellite Data by Gryspeerdt, Edward, McCoy, Daniel T., Crosbie, Ewan, Moore, Richard H., Nott, Graeme J., Painemal, David, Small-Griswold, Jennifer D, Sorooshian, Armin, Ziemba, Luke

“…Cloud droplet number concentration (Nd) is of central importance to observation-based estimates of aerosol indirect effects, being used to quantify both the…”
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Diffusion tensor imaging determines three‐dimensional architecture of human cervix: a cross‐sectional study by Nott, JP, Pervolaraki, E, Benson, AP, Bonney, EA, Pickering, JD, Wilkinson, N, Simpson, NAB

“…Objective To determine the microarchitecture of the cervix using high‐resolution diffusion tensor (DT) magnetic resonance imaging (MRI). Design Cross‐sectional…”
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Ion binding with charge inversion combined with screening modulates DEAD box helicase phase transitions by Crabtree, Michael D., Holland, Jack, Pillai, Arvind S., Kompella, Purnima S., Babl, Leon, Turner, Noah N., Eaton, James T., Hochberg, Georg K.A., Aarts, Dirk G.A.L., Redfield, Christina, Baldwin, Andrew J., Nott, Timothy J.

“…Membraneless organelles, or biomolecular condensates, enable cells to compartmentalize material and processes into unique biochemical environments. While…”
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Variational Approximation for Mixtures of Linear Mixed Models by Tan, Siew Li, Nott, David J.

“…Mixtures of linear mixed models (MLMMs) are useful for clustering grouped data and can be estimated by likelihood maximization through the…”
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Effects of multiple hydrogen absorption/desorption cycles on the mechanical properties of the alloy system palladium/silver (wt%=10–25) by Wald, K., Kubik, J., Paciulli, D., Talukder, M., Nott, J., Massicotte, F., Rebeiz, K., Nesbit, S., Craft, A.

“…Changes to the strength, hardness and ductility of a series of well-annealed palladium–silver alloys have been investigated as a function of the number of…”
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Water vapor intrusions into the High Arctic during winter by Doyle, J. G., Lesins, G., Thackray, C. P., Perro, C., Nott, G. J., Duck, T. J., Damoah, R., Drummond, J. R.

“…The meridional transport of water vapor into the High Arctic, accompanied by dry enthalpy and clouds, impacts the surface radiative forcing. The evolution of…”
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Versatility in phospho-dependent molecular recognition of the XRCC1 and XRCC4 DNA-damage scaffolds by aprataxin-family FHA domains by Cherry, Amy L., Nott, Timothy J., Kelly, Geoffrey, Rulten, Stuart L., Caldecott, Keith W., Smerdon, Stephen J.

“…•Aprataxin and APLF FHA domains show distinct specificities for XRCC4 and XRCC1.•Specificity is modulated by multi-site phosphorylation.•The crystal structure…”
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Molecular and isotopic stratigraphy in an ombrotrophic mire for paleoclimate reconstruction by Xie, Shucheng, Nott, Chris J, Avsejs, Luke A, Maddy, Darrel, Chambers, Frank M, Evershed, Richard P

“…A 40 cm deep Sphagnum-dominated peat monolith from Bolton Fell Moss in Northern England was systematically investigated by lipid molecular stratigraphy and…”
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BSR and BHPR guidelines for the management of giant cell arteritis by Dasgupta, Bhaskar, Borg, Frances A., Hassan, Nada, Alexander, Leslie, Barraclough, Kevin, Bourke, Brian, Fulcher, Joan, Hollywood, Jane, Hutchings, Andrew, James, Pat, Kyle, Valerie, Nott, Jennifer, Power, Michael, Samanta, Ash

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Generalized smooth finite mixtures by Villani, Mattias, Kohn, Robert, Nott, David J.

“…We propose a general class of models and a unified Bayesian inference methodology for flexibly estimating the density of a response variable conditional on a…”
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Meta-analysis and gene set enrichment relative to er status reveal elevated activity of MYC and E2F in the "basal" breast cancer subgroup by Alles, M Chehani, Gardiner-Garden, Margaret, Nott, David J, Wang, Yixin, Foekens, John A, Sutherland, Robert L, Musgrove, Elizabeth A, Ormandy, Christopher J

“…Breast cancers lacking the estrogen receptor (ER) can be distinguished from other breast cancers on the basis of poor prognosis, high grade, distinctive…”
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BSR and BHPR guidelines for the management of polymyalgia rheumatica by Dasgupta, Bhaskar, Borg, Frances A., Hassan, Nada, Barraclough, Kevin, Bourke, Brian, Fulcher, Joan, Hollywood, Jane, Hutchings, Andrew, Kyle, Valerie, Nott, Jennifer, Power, Michael, Samanta, Ash

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Stratospheric gravity wave characteristics and seasonal variations observed by lidar at the South Pole and Rothera, Antarctica by Yamashita, Chihoko, Chu, Xinzhao, Liu, Han-Li, Espy, Patrick J., Nott, Graeme J., Huang, Wentao

“…We present an observational study of stratospheric gravity wave spectra and seasonal variations of potential energy density at the South Pole (90°S) and…”
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