Search Results - "Notoya, Mitsuru"

Ghrelin O-acyltransferase knockout mice show resistance to obesity when fed high-sucrose diet by Kouno, Tetsuya, Akiyama, Nobuteru, Ito, Takahito, Okuda, Tomohiko, Nanchi, Isamu, Notoya, Mitsuru, Oka, Shogo, Yukioka, Hideo

“…Ghrelin is an appetite-stimulating hormone secreted from stomach. Since the discovery that acylation of the serine-3 residue by ghrelin O-acyltransferase…”
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The role of acylated-ghrelin in the regulation of sucrose intake by Kouno, Tetsuya, Akiyama, Nobuteru, Ito, Takahito, Fujieda, Kumiko, Nanchi, Isamu, Okuda, Tomohiko, Notoya, Mitsuru, Iwasaki, Takanori, Yukioka, Hideo

“…The octanoyl modification of ghrelin by ghrelin O-acyltransferase (GOAT) is essential for exerting its physiologic actions. Since exogenous acylated-ghrelin…”
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Potent Modification of Low Density Lipoprotein by Group X Secretory Phospholipase A2 Is Linked to Macrophage Foam Cell Formation by Hanasaki, Kohji, Yamada, Katsutoshi, Yamamoto, Shigenori, Ishimoto, Yoshikazu, Saiga, Akihiko, Ono, Takashi, Ikeda, Minoru, Notoya, Mitsuru, Kamitani, Shigeki, Arita, Hitoshi

“…The deposition of cholesterol ester within foam cells of the artery wall is fundamental to the pathogenesis of atherosclerosis. Modifications of low density…”
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Group V and X secretory phospholipase A2s-induced modification of high-density lipoprotein linked to the reduction of its antiatherogenic functions by Ishimoto, Yoshikazu, Yamada, Katsutoshi, Yamamoto, Shigenori, Ono, Takashi, Notoya, Mitsuru, Hanasaki, Kohji

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Intussusceptive capillary growth is required for glomerular repair in rat Thy-1.1 nephritis by Notoya, Mitsuru, Shinosaki, Toshihiro, Kobayashi, Tatsuo, Sakai, Tatsuo, Kurihara, Hidetake

“…Intussusceptive capillary growth is required for glomerular repair in rat Thy-1.1 nephritis. Injection of anti-Thy-1.1 antibodies to rats causes mesangiolysis,…”
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Sialyl Lewis X-Carboxymethylpullulan Conjugate: A Novel Homing Device to Spleen and Lymph Nodes by Horie, Kazutoshi, Sakagami, Masahiro, Masuda, Kazuyoshi, Notoya, Mitsuru, Hamana, Hiroshi, Yoshikawa, Takayoshi, Hirano, Koichiro

“…We have previously found that carboxymethylpullulan (CMPul) conjugated with sialyl Lewis X (Neu5Acα2-3Galβ1-4(Fucα1-3)GlcNAc-, 2-3SLex) preferentially…”
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Clearance of group X secretory phospholipase A2 via mouse phospholipase A2 receptor by Yokota, Yasunori, Notoya, Mitsuru, Higashino, Ken-ichi, Ishimoto, Yoshikazu, Nakano, Kazumi, Arita, Hitoshi, Hanasaki, Kohji

“…Given the potent hydrolyzing activity toward phosphatidylcholine, group X secretory phospholipase A2 (sPLA2‐X) elicits a marked release of arachidonic acid…”
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A Novel Acetyl-CoA Carboxylase 2 Selective Inhibitor Improves Whole-Body Insulin Resistance and Hyperglycemia in Diabetic Mice through Target-Dependent Pathways by Takagi, Hiroyuki, Tanimoto, Keiichi, Shimazaki, Atsuyuki, Tonomura, Yutaka, Momosaki, Sotaro, Sakamoto, Shingo, Abe, Kohji, Notoya, Mitsuru, Yukioka, Hideo

“…Excess intramyocellular lipid (IMCL) deposition in skeletal muscle is closely associated with insulin resistance. Pharmacological inhibition of acetyl-CoA…”
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1775-P: Impact of Acetyl-CoA Carboxylase 2 Inhibition on Skeletal Muscle Diacylglycerol and Ceramide Levels and Its Potential Contribution to Improved Glucose Metabolism by TAKAGI, HIROYUKI, IKEHARA, TATSUYA, HASHIMOTO, KUMI, SHIMAZAKI, ATSUYUKI, KASHIWAGI, YUTO, NISHIURA, YUJI, NOTOYA, MITSURU, YUKIOKA, HIDEO

“…Intramyocellular lipid (IMCL) accumulation in skeletal muscle is closely associated with the development of insulin resistance. In particular, bioactive lipids…”
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N-methyl-2-pyridone-5-carboxamide (N-Me-2PY) has potent anti-fibrotic and anti-inflammatory activity in a fibrotic kidney model: is it an old uremic toxin? by Yoshimura, Norito, Yamada, Katsutoshi, Ono, Takashi, Notoya, Mitsuru, Yukioka, Hideo, Takahashi, Rina, Wakino, Shu, Kanda, Takeshi, Itoh, Hiroshi

“…Background Uremic toxins accumulate in renal tissues and cells due to chronic kidney disease (CKD). Abnormalities in nicotinamide adenine dinucleotide (NAD +)…”
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Effects of Efonidipine Hydrochloride on Renal Arteriolar Diameters in Spontaneously Hypertensive Rats by NAKAMURA, Masuhisa, NOTOYA, Mitsuru, KOHDA, Yuka, YAMASHITA, Junji, TAKASHITA, Yuko, GEMBA, Munekazu

“…Efonidipine, a calcium antagonist, has been reported to dilate not only afferent but also efferent arterioles, thereby reducing glomerular hydrostatic…”
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Glomerular epithelial cell injury accelerates the progression of antibody-induced mesangial proliferative nephritis by Shinosaki, Toshihiro, Notoya, Mitsuru, Nomura, Yasuharu, Miyai, Ikuko, Kobayashi, Tatsuo, Kurihara, Hidetake

“…Anti-Thy-1.1 antibody induces mesangioproliferative glomerulonephritis; however, the mesangial lesion is spontaneously recovered to the normal feature…”
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Microwave-Stimulated Fixation and Histochemical Application to Biological Specimens by Hasegawa, Hiroshi, Mizuhira, Vinci, Notoya, Mitsuru

“…More than a decade ago, we introduced a technique using a computer controlled household microwave oven for biological tissue fixation. This microwave…”
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Microwave fixation and localization of calcium in synaptic vesicles by Mizuhira, V, Hasegawa, H, Notoya, M

“…The distribution of Ca2+ ions is demonstrated in the synaptic terminals by means of a 2-step chemical precipitation of Ca2+ ions in nervous tissue…”
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High resolution localization of endothelin receptors in rat renal medulla by Yukimura, Tokihito, Notoya, Mitsuru, Mizojiri, Kenji, Mizuhira, Vinci, Matsuura, Takeshi, Ebara, Tsuneyuki, Miura, Katsuyuki, Kim, Shokei, Iwao, Hiroshi, Song, Keifu

“…High resolution localization of endothelin receptors in rat renal medulla. The cellular localization of endothelin receptors in the inner medulla of the rat…”
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Microwave Fixation and Localization of Calcium in Synaptic Terminals and Muscular Cells by Electron Probe X-Ray Microanalysis and Electron Energy-Loss Spectroscopy Imaging by Mizuhira, Vinci, Hasegawa, Hiroshi, Notoya, Mitsuru

“…The distribution of calcium ions in the rat brain synaptic terminals, in their synaptic vesicles, membranes and mitochondria; and in the sarcoplasmic reticula,…”
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Irbesartan enhances GLUT4 translocation and glucose transport in skeletal muscle cells by Kobayashi, Tatsuo, Akiyama, Yuko, Akiyama, Nobuteru, Katoh, Hideaki, Yamamoto, Sachiko, Funatsuki, Kenzo, Yanagimoto, Toru, Notoya, Mitsuru, Asakura, Kenji, Shinosaki, Toshihiro, Hanasaki, Kohji

“…Irbesartan, an angiotensin II type 1 receptor blocker has been reported to alleviate metabolic disorder in animal studies and human clinical trials. Although…”
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Cortactin interacts with podocalyxin and mediates morphological change of podocytes through its phosphorylation by Kobayashi, Tatsuo, Notoya, Mitsuru, Shinosaki, Toshihiro, Kurihara, Hidetake

“…Morphological change of podocytes is closely correlated with the development of proteinuria. Podocalyxin is a major sialoglycoprotein of the podocytes and is…”
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Autoradiographic Studies on the Binding Sites of 125I-Adrenomedullin in Rat Tissues by Hasegawa, Hiroshi, Mizuhira, Vinci, Notoya, Mitsuru, Inazawa, Kazuhiro, Mizojiri, Kenji, Kitamura, Kazuo, Eto, Tanenao, Kangawa, Kenji

“…Adrenomedullin (AM) is a novel hypotensive peptide isolated from the human pheochromocytoma. In the present study, 125I-AM was intravenously administered to…”
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Group V and X secretory phospholipase A(2)s-induced modification of high-density lipoprotein linked to the reduction of its antiatherogenic functions by Ishimoto, Yoshikazu, Yamada, Katsutoshi, Yamamoto, Shigenori, Ono, Takashi, Notoya, Mitsuru, Hanasaki, Kohji

“…The quantitative or qualitative decline of high-density lipoprotein (HDL) is linked to the pathogenesis of atherosclerosis because of its antiatherogenic…”
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