Search Results - "Noti, John D."

Efficacy of face masks, neck gaiters and face shields for reducing the expulsion of simulated cough-generated aerosols by Lindsley, William G., Blachere, Francoise M., Law, Brandon F., Beezhold, Donald H., Noti, John D.

“…Face masks are recommended to reduce community transmission of SARS-CoV-2. One of the primary benefits of face masks and other coverings is as source control…”
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High humidity leads to loss of infectious influenza virus from simulated coughs by Noti, John D, Blachere, Francoise M, McMillen, Cynthia M, Lindsley, William G, Kashon, Michael L, Slaughter, Denzil R, Beezhold, Donald H

“…The role of relative humidity in the aerosol transmission of influenza was examined in a simulated examination room containing coughing and breathing manikins…”
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Effects of Ultraviolet Germicidal Irradiation (UVGI) on N95 Respirator Filtration Performance and Structural Integrity by Lindsley, William G., Martin, Stephen B., Thewlis, Robert E., Sarkisian, Khachatur, Nwoko, Julian O., Mead, Kenneth R., Noti, John D.

“…The ability to disinfect and reuse disposable N95 filtering facepiece respirators (FFRs) may be needed during a pandemic of an infectious respiratory disease…”
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Efficacy of Face Shields Against Cough Aerosol Droplets from a Cough Simulator by Lindsley, William G., Noti, John D., Blachere, Francoise M., Szalajda, Jonathan V., Beezhold, Donald H.

“…Health care workers are exposed to potentially infectious airborne particles while providing routine care to coughing patients. However, much is not understood…”
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β-Defensin-1 Regulates Influenza Virus Infection in Human Bronchial Epithelial Cells through the STAT3 Signaling Pathway by Othumpangat, Sreekumar, Noti, John D

“…Understanding the host response to influenza A virus (IAV) infection is vital for developing intervention strategies. The primary barriers for invading…”
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ICAM-1 regulates the survival of influenza virus in lung epithelial cells during the early stages of infection by Othumpangat, Sreekumar, Noti, John D, McMillen, Cynthia M, Beezhold, Donald H

“…Abstract Intercellular cell adhesion molecule-1 (ICAM-1) is an inducible cell surface glycoprotein that is expressed on many cell types. Influenza virus…”
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Viable influenza A virus in airborne particles expelled during coughs versus exhalations by Lindsley, William G., Blachere, Francoise M., Beezhold, Donald H., Thewlis, Robert E., Noorbakhsh, Bahar, Othumpangat, Sreekumar, Goldsmith, William T., McMillen, Cynthia M., Andrew, Michael E., Burrell, Carmen N., Noti, John D.

“…Background To prepare for a possible influenza pandemic, a better understanding of the potential for the airborne transmission of influenza from person to…”
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A Cough Aerosol Simulator for the Study of Disease Transmission by Human Cough-Generated Aerosols by Lindsley, William G., Reynolds, Jeffrey S., Szalajda, Jonathan V., Noti, John D., Beezhold, Donald H.

“…Aerosol particles expelled during human coughs are a potential pathway for infectious disease transmission. However, the importance of airborne transmission is…”
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Influenza Virus-Induced Novel miRNAs Regulate the STAT Pathway by Othumpangat, Sreekumar, Beezhold, Donald H, Umbright, Christina M, Noti, John D

“…MicroRNAs (miRNAs) are essential regulators of gene expression in humans and can control pathogenesis and host-virus interactions. Notably, the role of…”
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Maximizing Fit for Cloth and Medical Procedure Masks to Improve Performance and Reduce SARS-CoV-2 Transmission and Exposure, 2021 by Brooks, John T, Beezhold, Donald H, Noti, John D, Coyle, Jayme P, Derk, Raymond C, Blachere, Francoise M, Lindsley, William G

“…Universal masking is one of the prevention strategies recommended by CDC to slow the spread of SARS-CoV-2, the virus that causes coronavirus disease 2019…”
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Healthcare personnel exposure in an emergency department during influenza season by Rule, Ana M, Apau, Otis, Ahrenholz, Steven H, Brueck, Scott E, Lindsley, William G, de Perio, Marie A, Noti, John D, Shaffer, Ronald E, Rothman, Richard, Grigorovitch, Alina, Noorbakhsh, Bahar, Beezhold, Donald H, Yorio, Patrick L, Perl, Trish M, Fisher, Edward M

“…Healthcare personnel are at high risk for exposure to influenza by direct and indirect contact, droplets and aerosols, and by aerosol generating procedures…”
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Topical exposure to triclosan inhibits Th1 immune responses and reduces T cells responding to influenza infection in mice by Shane, Hillary L, Othumpangat, Sreekumar, Marshall, Nikki B, Blachere, Francoise, Lukomska, Ewa, Weatherly, Lisa M, Baur, Rachel, Noti, John D, Anderson, Stacey E

“…Healthcare workers concurrently may be at a higher risk of developing respiratory infections and allergic disease, such as asthma, than the general public…”
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Efficacy of Ventilation, HEPA Air Cleaners, Universal Masking, and Physical Distancing for Reducing Exposure to Simulated Exhaled Aerosols in a Meeting Room by Coyle, Jayme P, Derk, Raymond C, Lindsley, William G, Blachere, Francoise M, Boots, Theresa, Lemons, Angela R, Martin, Jr, Stephen B, Mead, Kenneth R, Fotta, Steven A, Reynolds, Jeffrey S, McKinney, Walter G, Sinsel, Erik W, Beezhold, Donald H, Noti, John D

“…There is strong evidence associating the indoor environment with transmission of SARS-CoV-2, the virus that causes COVID-19. SARS-CoV-2 can spread by exposure…”
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Upregulation of miRNA-4776 in Influenza Virus Infected Bronchial Epithelial Cells Is Associated with Downregulation of NFKBIB and Increased Viral Survival by Othumpangat, Sreekumar, Bryan, Nicole B, Beezhold, Donald H, Noti, John D

“…Influenza A virus (IAV) infection remains a significant cause of morbidity and mortality worldwide. One key transcription factor that is activated upon IAV…”
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Inhibition of influenza A virus matrix and nonstructural gene expression using RNA interference by McMillen, Cynthia M, Beezhold, Donald H, Blachere, Francoise M, Othumpangat, Sreekumar, Kashon, Michael L, Noti, John D

“…Abstract Influenza antiviral drugs that use protein inhibitors can lose their efficacy as resistant strains emerge. As an alternative strategy, we investigated…”
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Efficacy of Portable Air Cleaners and Masking for Reducing Indoor Exposure to Simulated Exhaled SARS-CoV-2 Aerosols — United States, 2021 by Lindsley, William G, Derk, Raymond C, Coyle, Jayme P, Martin, Stephen B., Jr, Mead, Kenneth R, Blachere, Francoise M, Beezhold, Donald H, Brooks, John T, Boots, Theresa, Noti, John D

“…What is already known about this topic? Ventilation systems can be supplemented with portable high efficiency particulate air (HEPA) cleaners to reduce the…”
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Differential Expression of Serum Exosome microRNAs and Cytokines in Influenza A and B Patients Collected in the 2016 and 2017 Influenza Seasons by Othumpangat, Sreekumar, Lindsley, William G, Beezhold, Donald H, Kashon, Michael L, Burrell, Carmen N, Mubareka, Samira, Noti, John D

“…MicroRNAs (miRNAs) have remarkable stability and are key regulators of mRNA transcripts for several essential proteins required for the survival of cells and…”
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Survival of Staphylococcus aureus on the outer shell of fire fighter turnout gear after sanitation in a commercial washer/extractor by Farcas, Daniel, Blachere, Francoise M, Kashon, Michael L, Sbarra, Deborah, Schwegler-Berry, Diane, Stull, Jeffrey O, Noti, John D

“…Methicillin-resistant contamination on surfaces including turnout gear had been found throughout a number of fire stations. As such, the outer shell barrier of…”
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Efficacy of powered air-purifying respirators (PAPRs) for source control of simulated respiratory aerosols by Lindsley, William G., Blachere, Francoise M., Derk, Raymond C., Mnatsakanova, Anna, Noti, John D.

“…Loose-fitting powered air-purifying respirators (PAPRs) are a popular alternative to the use of filtering facepiece respirators for health care workers…”
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Lung epithelial cells resist influenza A infection by inducing the expression of cytochrome c oxidase VIc which is modulated by miRNA 4276 by Othumpangat, Sreekumar, Noti, John D, Beezhold, Donald H

“…Abstract Influenza virus infection induces several changes in host miRNA profile, host cell death and tissue damage. Cytochrome c is a regulator of the…”
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