Search Results - "Not, Olivier van"
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Adverse Events in Anti-PD-1-Treated Adjuvant and First-Line Advanced Melanoma Patients
Published in Cancers (01-08-2024)“…: The difference in incidence and severity of anti-PD-1 therapy-related adverse events (irAEs) between adjuvant and advanced treated melanoma patients remains…”
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Response to immune checkpoint inhibitors in acral melanoma: A nationwide cohort study
Published in European journal of cancer (1990) (01-05-2022)“…Recent reports suggest the limited efficacy of immune checkpoints inhibitors in advanced acral melanoma (AM). This study aims to investigate the clinical…”
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The unfavorable effects of COVID-19 on Dutch advanced melanoma care
Published in International journal of cancer (01-03-2022)“…The COVID-19 pandemic had a severe impact on medical care. Our study aims to investigate the impact of COVID-19 on advanced melanoma care in the Netherlands…”
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Adjuvant treatment for melanoma in clinical practice – Trial versus reality
Published in European journal of cancer (1990) (01-11-2021)“…Little is known about outcomes of adjuvant-treated melanoma patients beyond the clinical trial setting. Since 2019, adjuvant-treated melanoma patients have…”
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Adjuvant treatment with anti-PD-1 in acral melanoma: A nationwide study
Published in International journal of cancer (15-10-2024)“…Previous studies demonstrated limited efficacy of immune checkpoint inhibitors in unresectable acral melanoma (AM); it remains unclear how this translates to…”
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A prediction model for response to immune checkpoint inhibition in advanced melanoma
Published in International journal of cancer (15-05-2024)“…Predicting who will benefit from treatment with immune checkpoint inhibition (ICI) in patients with advanced melanoma is challenging. We developed a…”
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BRAF/MEK inhibitor rechallenge in advanced melanoma patients
Published in Cancer (01-05-2024)“…Background Effectivity of BRAF(/MEK) inhibitor rechallenge has been described in prior studies. However, structured data are largely lacking. Methods Data from…”
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Association of Immune-Related Adverse Event Management With Survival in Patients With Advanced Melanoma
Published in JAMA oncology (01-12-2022)“…Management of checkpoint inhibitor-induced immune-related adverse events (irAEs) is primarily based on expert opinion. Recent studies have suggested…”
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Response to checkpoint inhibition and targeted therapy in melanoma patients with concurrent haematological malignancies
Published in European journal of cancer (1990) (01-06-2023)“…Patients diagnosed with haematologic malignancies (HMs) have a higher risk of developing subsequent solid tumours, such as melanoma. Patients with HM were…”
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Time interval from primary melanoma to first distant recurrence in relation to patient outcomes in advanced melanoma
Published in International journal of cancer (15-06-2023)“…Since the introduction of BRAF(/MEK) inhibition and immune checkpoint inhibition (ICI), the prognosis of advanced melanoma has greatly improved. Melanoma is…”
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Steroid Dose and Duration, Immortal Time Bias, and Survival After High-grade Immune-Related Adverse Events-Reply
Published in JAMA oncology (01-05-2023)Get more information
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Adjuvant treatment of in‐transit melanoma: Narrowing the knowledge gap left by clinical trials
Published in International journal of cancer (15-07-2023)“…Few clinical trials address efficacy of adjuvant systemic treatment in patients with in‐transit melanoma (ITM). This study describes adjuvant systemic therapy…”
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Is a History of Optimal Staging by Sentinel Lymph Node Biopsy in the Era Prior to Adjuvant Therapy Associated with Improved Outcome Once Melanoma Patients have Progressed to Advanced Disease?
Published in Annals of surgical oncology (2023)“…Introduction Sentinel lymph node biopsy (SLNB) is important for staging in patients with primary cutaneous melanoma. Did having previously undergone SLNB also…”
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Adjuvant BRAF-MEK Inhibitors versus Anti PD-1 Therapy in Stage III Melanoma: A Propensity-Matched Outcome Analysis
Published in Cancers (07-01-2023)“…Adjuvant BRAF/MEK- and anti-PD-1 inhibition have significantly improved recurrence-free survival (RFS) compared to placebo in resected stage III BRAF-mutant…”
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A Survival Tree of Advanced Melanoma Patients with Brain Metastases Treated with Immune Checkpoint Inhibitors
Published in Cancers (26-05-2023)“…The efficacy of immune checkpoint inhibitors (ICIs) in patients with advanced melanoma that develop brain metastases (BM) remains unpredictable. In this study,…”
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Long-Term Survival in Patients With Advanced Melanoma
Published in JAMA network open (01-08-2024)“…Long-term survival data from clinical trials show that survival curves of patients with advanced melanoma treated with immune checkpoint inhibitors (ICIs)…”
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BRAF and NRAS Mutation Status and Response to Checkpoint Inhibition in Advanced Melanoma
Published in JCO precision oncology (01-09-2022)“…Little is known about the effect of specific gene mutations on efficacy of immune checkpoint inhibitors in patients with advanced melanoma. All patients with…”
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Improving survival in advanced melanoma patients: a trend analysis from 2013 to 2021
Published in EClinicalMedicine (01-03-2024)“…The prognosis of advanced melanoma patients has significantly improved over the years. We aimed to evaluate the survival per year of diagnosis. All…”
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