Search Results - "Nossiff, N"
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1
Targeted accumulation of polyethylene glycol-coated immunoliposomes in infarcted rabbit myocardium
Published in The FASEB journal (01-06-1992)“…The less than optimal accumulation of immunoliposome-associated reagents at target sites has often been attributed to the rapid in vivo clearance of…”
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2
MR lymphography: study of a high-efficiency lymphotrophic agent
Published in Radiology (01-04-1994)“…To investigate the utility of a monocrystalline iron oxide nanoparticle (MION) as a contrast agent in magnetic resonance (MR) imaging of lymph nodes…”
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3
Gamma Imaging with Negatively Charge-Modified Monoclonal Antibody: Modification with Synthetic Polymers
Published in The Journal of nuclear medicine (1978) (01-09-1991)“…Antimyosin Fab has been modified to carry highly negatively charged synthetic polymers containing DTPAs (DTPA-PL) as chelating agents, of starting molecular…”
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4
MR imaging of slow axonal transport in vivo
Published in Experimental neurology (01-10-1993)“…Three magnetopharmaceuticals based on a monocrystalline iron oxide nanocompound (MION) are evaluated as potential contrast agents for demonstrating axonal…”
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5
Determinants of in vivo MR imaging of slow axonal transport
Published in Radiology (01-11-1994)“…To investigate specific surface characteristics of magnetic contrast agents based on a monocrystalline iron oxide nanoparticle (MION) that may determine their…”
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6
Radionuclide Imaging of Experimental Atherosclerosis with Nonspecific Polyclonal Immunoglobulin G
Published in The Journal of nuclear medicine (1978) (01-06-1989)“…The utility of nonspecific polyclonal IgG for external imaging of experimental atherosclerosis was tested in a series of rabbits after balloon catheter…”
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7
Evaluation of Myocardial Infarct Size Before and After Reperfusion: Dual-Tracer Imaging with Radiolabeled Antimyosin Antibody
Published in The Journal of nuclear medicine (1978) (01-06-1994)“…Antimyosin antibody is a specific marker of myocardial necrosis that is based on the loss of integrity of the sarcolemmal membrane. Because antimyosin can be…”
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8
Targeting of macromolecular carriers and liposomes by antibodies to myosin heavy chain
Published in The American journal of physiology (01-10-1991)“…Macromolecular carriers and liposomes were covalently coupled to monoclonal antibodies against cardiac myosin heavy chain. Deferoxamine-modified polymers bound…”
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9
Use of isothiocyanatobenzyl-DTPA derivatized monoclonal antimyosin Fab for enhanced in vivo target localization
Published in The Journal of nuclear medicine (1978) (01-02-1990)“…Monoclonal antimyosin Fab (AM-Fab) was radiolabeled with 111In via a new bifunctional chelating agent, isothiocyanatobenzyl-DTPA (SCN-DTPA), and used to…”
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10
Monoclonal antibody modification with chelate-linked high-molecular-weight polymers: major increases in polyvalent cation binding without loss of antigen binding
Published in Hybridoma (01-06-1987)“…Polyethyleneimine or polylysines of differing molecular sizes were substituted with either EDTA or DTPA and then with succinic acid groups. These polymers were…”
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11
In vivo targeting of acute myocardial infarction with negative-charge, polymer-modified antimyosin antibody: Use of different cross-linkers
Published in Journal of nuclear cardiology (1995)“…Background Cell surfaces and intercellular matrixes contain acidic residues, making them negatively charged. Antibodies are basic, positively charged…”
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12
Modification of monoclonal antimyosin antibody: enhanced specificity of localization and scintigraphic visualization in acute experimental myocardial infarction
Published in Journal of molecular and cellular cardiology (01-02-1989)“…Positively charged polymers have been shown to interact nonselectively with cells in vitro by means of an electrostatic binding to a negatively charged cell…”
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13
MION-ASF: biokinetics of an MR receptor agent
Published in Magnetic resonance imaging (1993)“…Receptor-directed MR contrast agents are currently being designed to improve sensitivity and specificity of MR imaging and to provide for functional MR…”
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14
AUR Memorial Award 1993. A drug system (PDH) for interventional radiology. Synthesis, properties, and efficacy
Published in Investigative radiology (01-12-1993)“…The authors synthesized and tested a novel hydrogel system proposed for use in extra- and intravascular radiologic interventions, such as chemoembolizations…”
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15
Correlation of immunoreactivity and polymer formation to DTPA modification of a monoclonal antibody
Published in International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology (1991)“…The protocol used for coupling of monoclonal antibodies with mixed anhydride of DTPA for subsequent radiolabeling with indium-111 affects the integrity of the…”
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