Search Results - "Noske, D"

Third harmonic generation imaging for fast, label-free pathology of human brain tumors by Kuzmin, N V, Wesseling, P, Hamer, P C de Witt, Noske, D P, Galgano, G D, Mansvelder, H D, Baayen, J C, Groot, M L

“…In brain tumor surgery, recognition of tumor boundaries is key. However, intraoperative assessment of tumor boundaries by the neurosurgeon is difficult…”
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Radio-sensitizing effect of MEK inhibition in glioblastoma in vitro and in vivo by Houweling, M., Abdul, U. K., Brahm, C., Lagerweij, T., Heukelom, S., Koken, P. W., Honeywell, R., Wedekind, L. E., Peters, G. J., Verheul, H., Sminia, P., Noske, D., Wurdinger, T., Westerman, B. A.

“…Introduction Glioblastoma (GBM) is an incurable cancer type. New therapeutic options are investigated, including targeting the mitogen-activated protein kinase…”
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Mature astrocytes in the adult human neocortex express the early neuronal marker doublecortin by Verwer, R. W. H., Sluiter, A. A., Balesar, R. A., Baayen, J. C., Noske, D. P., Dirven, C. M. F., Wouda, J., van Dam, A. M., Lucassen, P. J., Swaab, D. F.

“…Doublecortin (DCX) is a microtubule-associated protein expressed by migrating neuroblasts and is considered to be a reliable marker of neurogenesis. DCX has…”
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Implementation of a multi-institutional diffuse intrinsic pontine glioma autopsy protocol and characterization of a primary cell culture by Caretti, V., Jansen, M. H. A., van Vuurden, D. G., Lagerweij, T., Bugiani, M., Horsman, I., Wessels, H., van der Valk, P., Cloos, J., Noske, D. P., Vandertop, W. P., Wesseling, P., Wurdinger, T., Hulleman, E., Kaspers, G. J. L.

“…V. Caretti, M. H. A. Jansen, D. G. van Vuurden, T. Lagerweij, M. Bugiani, I. Horsman, H. Wessels, P. van der Valk, J. Cloos, D. P. Noske, W. P. Vandertop, P…”
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Suicidal gene therapy in an NF-[kappa]B-controlled tumor environment as monitored by a secreted blood reporter by Badr, C E, Niers, J M, Morse, D, Koelen, J A, Vandertop, P, Noske, D, Wurdinger, T, Zalloua, P A, Tannous, B A

“…The nuclear factor-kB (NF-kB) is known to be activated in many cancer types including lung, ovarian, astrocytomas, melanoma, prostate as well as glioblastoma,…”
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Suicidal gene therapy in an NF-κB-controlled tumor environment as monitored by a secreted blood reporter by Badr, C E, Niers, J M, Morse, D, Koelen, J A, Vandertop, P, Noske, D, Wurdinger, T, Zalloua, P A, Tannous, B A

“…The nuclear factor-κB (NF-κB) is known to be activated in many cancer types including lung, ovarian, astrocytomas, melanoma, prostate as well as glioblastoma,…”
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A Crystallographic Snapshot of SARS-CoV-2 Main Protease Maturation Process by Noske, G.D., Nakamura, A.M., Gawriljuk, V.O., Fernandes, R.S., Lima, G.M.A., Rosa, H.V.D., Pereira, H.D., Zeri, A.C.M., Nascimento, A.F.Z., Freire, M.C.L.C., Fearon, D., Douangamath, A., von Delft, F., Oliva, G., Godoy, A.S.

“…[Display omitted] •Crystal structure of the immature form of Mpro (1.6A).•Immature form of Mpro in complex with 5 fragments.•Crystal structure of Mpro C145S…”
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Transpedicular wedge resection osteotomy for the treatment of a kyphotic Andersson lesion-complicating ankylosing spondylitis by Van Royen, B J, Kastelijns, R C A, Noske, D P, Oner, F C, Smit, T H

“…Two cases with a long-standing thoracolumbar kyphosis due to ankylosing spondylitis are presented with a symptomatic localized destructive kyphotic lesion of…”
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Basilar impression in osteogenesis imperfecta: can it be treated with halo traction and posterior fusion? by Noske, D P, van Royen, B J, Bron, J L, Vandertop, W P

“…Basilar impression (BI) and hydrocephalus complicating osteogenesis imperfecta (OI) is usually treated by anterior transoral decompression and posterior…”
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Discovery of PLpro and Mpro Inhibitors for SARS-CoV‑2 by Puhl, Ana C., Godoy, Andre S., Noske, Gabriela D., Nakamura, Aline M., Gawriljuk, Victor O., Fernandes, Rafaela S., Oliva, Glaucius, Ekins, Sean

“…There are very few small-molecule antivirals for SARS-CoV-2 that are either currently approved (or emergency authorized) in the US or globally, including…”
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High-throughput Antiviral Assays to Screen for Inhibitors of Zika Virus Replication by Fernandes, Rafaela S, Noske, Gabriela D, Gawriljuk, Victor O, de Oliveira, Ketllyn I Z, Godoy, Andre S, Mesquita, Nathalya C M R, Oliva, Glaucius

“…Antiviral drug discovery requires the development of reliable biochemical and cellular assays that can be performed in high-throughput screening (HTS) formats…”
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Discovery of PL pro and M pro Inhibitors for SARS-CoV-2 by Puhl, Ana C, Godoy, Andre S, Noske, Gabriela D, Nakamura, Aline M, Gawriljuk, Victor O, Fernandes, Rafaela S, Oliva, Glaucius, Ekins, Sean

“…There are very few small-molecule antivirals for SARS-CoV-2 that are either currently approved (or emergency authorized) in the US or globally, including…”
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Pyronaridine Protects against SARS-CoV‑2 Infection in Mouse by Puhl, Ana C., Gomes, Giovanni F., Damasceno, Samara, Godoy, Andre S., Noske, Gabriela D., Nakamura, Aline M., Gawriljuk, Victor O., Fernandes, Rafaela S., Monakhova, Natalia, Riabova, Olga, Lane, Thomas R., Makarov, Vadim, Veras, Flavio P., Batah, Sabrina S., Fabro, Alexandre T., Oliva, Glaucius, Cunha, Fernando Q., Alves-Filho, José C., Cunha, Thiago M., Ekins, Sean

“…There are currently relatively few small-molecule antiviral drugs that are either approved or emergency-approved for use against severe acute respiratory…”
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OS06.6.A LOCAL DELIVERY OF HRBMP4 AS AN ANTICANCER THERAPY IN PATIENTS WITH RECURRENT GLIOBLASTOMA: A FIRST-IN-HUMAN PHASE 1 DOSE ESCALATION TRIAL by Bos, E M, Binda, E, Verploegh, I S, Wembacher, E, Hoefnagel, D, Balvers, R K, Korporaal, A L, Conidi, A, Warnert, E A H, Trivieri, N, Visioli, A, Zaccarini, P, Caiola, L, van Wijck, R, van der Spek, P, Huylebroeck, D, Leenstra, S, Lamfers, M L M, Ram, Z, Westphal, M, Noske, D, Legnani, F, DiMeco, F, Vescovi, A L, Dirven, C M F

“…Abstract BACKGROUND This Phase 1 study evaluates the intra- and peritumoral administration by convection enhanced delivery (CED) of human recombinant Bone…”
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The ex-vivo-shunt-model: novel approach for assessing the thrombogenicity of vascular implants by Wilhelmi, M H, Gratz, K F, Mischke, R, von Depka, M, Noske, D, Francis, T, Haverich, A, Mertsching, H

“…Disadvantages associated with commercially available vascular implants necessitate alternative strategies to develop new vascular prostheses. Although many…”
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Time resolved spectral development of ultrashort pulse solitons in erbium fiber loop lasers by Noske, D.U., Pandit, N., Taylor, J.R.

“…Using a gated pumping technique, the time resolved spectral development of ultrashort pulses in an erbium fibre “figure of eight” laser have been examined in…”
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Photodynamic therapy of malignant glioma. A review of literature by Noske, D P, Wolbers, J G, Sterenborg, H J

“…Photodynamic therapy is a new form of cancer treatment which can serve as an adjuvant therapy for malignant glioma. It is based on the selective retention of a…”
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Functional multiplex reporter assay using tagged Gaussia luciferase by van Rijn, Sjoerd, Nilsson, Jonas, Noske, David P., Vandertop, W. Peter, Tannous, Bakhos A., Würdinger, Thomas

“…We have developed a multiplex reporter system to monitor multiple biological variables in real-time. The secreted Gaussia luciferase was fused to ten different…”
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SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids by Reimer, Katharina C., Nagai, James S., Varghese, Finny S., Overheul, Gijs J., Roverts, Rona, Willemsen, Brigith, Beukenboom, Marcel, Dunnen, Wilfred den, Triana, Sergio H., Timm, Marie-Cherelle, van den Berge, Bartholomeus T., Nlandu, Quincy, Heijnert, Joelle, Bindels, Eric M.J., Hoogenboezem, Remco M., Mooren, Fieke, Kuppe, Christoph, Grünberg, Katrien, Steenbergen, Eric J., Czogalla, Jan, Sommerdijk, Nico, Akiva, Anat, Boor, Peter, Huber, Tobias B., Bar-David, Elad, Barr, Haim, Boby, Melissa L., Borden, Bruce, Bowman, Gregory R., Brun, Juliane, BVNBS, Sarma, Carbery, Anna, Chernychenko, Eugene, Clyde, Austin, Coffland, Joseph E., Cole, Jason, Cox, Lisa, Dudgeon, Tim, Dunnett, Louise, Erez, Noam, Fate, Gwen, Ferrins, Lori, Foster, Richard, Foster, Holly, Gabizon, Ronen, Gawriljuk, Victor O., Gehrtz, Paul, Gileadi, Carina, Giroud, Charline, Glen, Robert, Gorichko, Marian, Griffen, Ed J., Heer, Jag, Hill, Michelle, Horrell, Sam, Jajack, Andrew, De Jonghe, Steven, Kantsadi, Anastassia L., Koekemoer, Lizbe, Lee, Alpha A., Lefker, Bruce A., Macdonald, Hannah Bruce, Maclean, Beth, McCorkindale, Willam, McGovern, Briana L., Michurin, Oleg, Morris, Aaron, Morris, Garret M., Neyts, Johan, Oliva, Glaucius, Overheul, Gijs J., Owen, David, Psenak, Vladimir, Pai, Ruby, Paran, Nir, Perry, Benjamin, Pingle, Maneesh, Politi, Boaz, Powell, Ailsa, Puni, Reut, Resnick, Efrat, Rosales, Romel, Schofield, Chris, Shafeev, Mikhail, Sittner, Assa, Skyner, Rachael, Spencer, John, Tamir, Hadas, Tennant, Rachael, Tumber, Anthony, van Rij, Ronald P., Voelz, Vincent, Volkamer, Andra, von Delft, Annette, White, Kris M., Wright, Nathan, Zidane, Hadeer, Costa, Ivan G., Schneider, Rebekka K., Smeets, Bart

“…Kidney failure is frequently observed during and after COVID-19, but it remains elusive whether this is a direct effect of the virus. Here, we report that…”
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Impact of extent of resection of glioblastoma multiforme (GBM) in the era of chemoradiation by Slotman, B. J., Eppinga, W. S., Reijneveld, J. C., Noske, D. P., Buter, J., Braam, L. M., Lagerwaard, F. J.

“…Abstract only e13029 Background: Controversy remains regarding the impact of the extent of resection (EOR) on survival in patients with GBM (Sanai 2008). The…”
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