Search Results - "Noshita, T."

Effect of nicotine on neuronal dysfunction induced by intracerebroventricular infusion of amyloid-β peptide in rats by Noshita, T, Murayama, N, Nakamura, S

“…The aim of the study was to investigate the effects of nicotine on learning and memory deficits induced by intracerebroventricular infusion of amyloid-β…”
Get more information

Selective toxicity of glycyrrhetinic acid against tumorigenic r/ m HM-SFME-1 cells is potentially attributed to downregulation of glutathione by Yamaguchi, H., Yu, T., Kidachi, Y., Akitaya, T., Yoshida, K., Kamiie, K., Noshita, T., Umetsu, H., Ryoyama, K.

“…Natural products from plants are expected to play significant roles in creating new, safe and improved chemopreventive and therapeutic antitumor agents…”
Get full text

New quinoline alkaloids from the leaves and stems of Orixa japonica [Rutaceae], orijanone, isopteleflorine and 3'-O-methylorixine by Noshita, T. (Aomori Univ. (Japan)), Tando, M, Suzuki, K, Murata, K, Funayama, S

“…Orixa japonica (Rutaceae) is a shrub widely distributed in Japan, and has been found to contain various quinoline alkaloids. We investigated the alkaloidal…”
Get full text

Progressive brain dysfunction following intracerebroventricular infusion of beta(1-42)-amyloid peptide by Nakamura, S, Murayama, N, Noshita, T, Annoura, H, Ohno, T

“…The behavioral, neurochemical and histological changes of rats subjected to 3 days treatment with intracerebroventricular infusion of beta-amyloid…”
Get full text

Quinoline Alkaloids of Orixa japonica by Funayama, Shinji, Murata, Kiyoshi, Noshita, Toshiro

Get full text

Mitochondrial peroxiredoxin‐3 protects hippocampal neurons from excitotoxic injury in vivo by Hattori, Fumiyuki, Murayama, Norihito, Noshita, Takafumi, Oikawa, Shinzo

“…Mitochondria are involved in excitotoxic damage of nerve cells. Following the breakdown of the calcium‐buffering ability of mitochondria, mitochondrial calcium…”
Get full text

Total synthesis of natural (+)-phomopsolide B, an antifeedant against elm bark beetle [Scolythus frontalis Blandford: Coleoptera] by Noshita, T. (Tohoku Univ., Sendai (Japan). Faculty of Agriculture), Sugiyama, T, Yamashita, K, Oritani, T

“…The total synthesis of natural (+)-phomopsolide B (2) is described. A 5,6-dihydro-2H-pyran-2-one framework was constructed by coupling chiral aldehyde 4 and…”
Get full text

Structural insight into the ligand-receptor interaction between glycyrrhetinic acid (GA) and the high-mobility group protein B1 (HMGB1)-DNA complex by Yamaguchi, Hideaki, Kidachi, Yumi, Kamiie, Katsuyoshi, Noshita, Toshiro, Umetsu, Hironori

“…Structural analysis of the high-mobility group protein B1 (HMGB1)-DNA complex and a docking simulation between glycyrrhetinic acid (GA) and the HMGB1-DNA…”
Get full text

Machilin G and four neolignans from young fruits of Magnolia denudata show various degrees of inhibitory activity on nitric oxide (NO) production by Noshita, T.(Aomori Univ. (Japan)), Funayama, S, Hirakawa, T, Kidachi, Y, Ryoyama, K

“…Denudatin A and B, denudadione B, fargesone A and machilin G were isolated from Magnolia denudata. These compounds showed inhibitory effects on nitric oxide…”
Get full text

New cytotoxic phenolic derivatives from matured fruits of Magnolia denudata by Noshita, T.(Aomori Univ. (Japan)), Kiyota, H, Kidachi, Y, Ryoyama, K, Funayama, S, Hanada, K, Murayama, T

“…Magnolia species are widely cultivated in Japan as garden plants, and have been found to contain various compounds, including alkaloids, terpenoids, lignans,…”
Get full text

Homology modeling and structural analysis of human P-glycoprotein by Yamaguchi, Hideaki, Kidachi, Yumi, Kamiie, Katsuyoshi, Noshita, Toshiro, Umetsu, Hironori

“…Homology modeling and structural analysis of human P-glycoprotein (hP-gp) were performed with a software package the Molecular Operating Environment (MOE). A…”
Get full text

The augmenting activity of 6-(Methylsulfinyl)hexyl isothiocyanate on cellular glutathione levels is less sensitive to thiol compounds than its cytotoxic activity by Kidachi, Y.(Aomori Univ. (Japan)), Noshita, T, Yamaguchi, H, Umetsu, H, Fuke, Y, Ryoyama, K

“…We analyzed the effects of thiol compounds on the biological activities of 6-(methylsulfinyl)hexyl isothiocyanate (6-MITC). Thiol compounds abolished the…”
Get full text

Progressive brain dysfunction following intracerebroventricular infusion of beta sub(1-42)-amyloid peptide by Nakamura, S, Murayama, N, Noshita, T, Annoura, H, Ohno, T

“…The behavioral, neurochemical and histological changes of rats subjected to 3 days treatment with intracerebroventricular infusion of beta-amyloid peptides(A…”
Get full text

Characterization of (−)-Matairesinol as a Potent Inhibitor of Casein Kinase I in Vitro by Yokoyama, Takamasa, Okano, Maiko, Noshita, Toshiro, Funayama, Shinji, Ohtsuki, Kenzo

“…The inhibitory effects of (−)-matairesinol (MTS) isolated from Thujopsis dolabrata var. hondai on the activities of four distinct Ser/Thr-protein kinases [two…”
Get full text

Rat Small Intestine Muscle Relaxation Alkaloids from Orixa japonica Leaves by FUNAYAMA, Shinji, TANAKA, Rioko, KUMEKAWA, Yasuhiro, NOSHITA, Toshiro, MORI, Tetsuya, KASHIWAGURA, Tadashi, MURATA, Kiyoshi

“…Two quinoline alkaloids, japonine (1) and eduline (2) were isolated from the methanol extract of the leaves of Orixa japonica as relaxants against rat small…”
Get full text

Cytotoxic Alkaloids of Pachysandra terminalis by FUNAYAMA, Shinji, NOSHITA, Toshiro, SHINODA, Kazuto, HAGA, Naomi, NOZOE, Shigeo, HAYASHI, Masahiko, KOMIYAMA, Kanki

“…Four steroidal alkaloids, epipachysamines B (1) and E (2), pachystermine A (3) and pachysamine E (4), were isolated as cytotoxic principles from the MeOH…”
Get full text

Adxanthromycins A and B, new inhibitors of ICAM-1/LFA-1 mediated cell adhesion molecule from Streptomyces sp. NA-148. II. Physico-chemical properties and structure elucidation by Takahashi, S, Nakano, T, Koiwa, T, Noshita, T, Funayama, S, Koshino, H, Nakagawa, A

“…Adxanthromycins A and B are new inhibitors of ICAM-1/LFA-1 mediated cell adhesion molecule isolated from the fermentation broth of Streptomyces sp. NA-148. The…”
Get more information

Reinvestigation of Phenolic Ferrier Reaction: Selective Synthesis of Aryl O-Δ2-Glycosides by Noshita, Toshiro, Sugiyama, Takeyoshi, Kitazumi, Yoshiharu, Oritani, Takayuki

“…Reinvestigation of the phenolic Ferrier reaction is described. Ferrier reaction between acetylglycals and phenols in toluene in the presence of a catalytic…”
Get full text