Search Results - "Noseda, Roberta"
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Immune Checkpoint Inhibitor-Related Cytokine Release Syndrome: Analysis of WHO Global Pharmacovigilance Database
Published in Frontiers in pharmacology (04-05-2020)“…Immune checkpoint inhibitors (ICIs) have proven effective in the treatment of numerous cancers; however, they have been associated with immune-related adverse…”
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Haemophagocytic lymphohistiocytosis in patients treated with immune checkpoint inhibitors: analysis of WHO global database of individual case safety reports
Published in Journal for immunotherapy of cancer (02-05-2019)“…Immune checkpoint inhibitor (ICI) use in clinical practice has unravelled a spectrum of immune-related adverse events (irAEs) due to immune system…”
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Evaluation of the safety profile of rotavirus vaccines: a pharmacovigilance analysis on American and European data
Published in Scientific reports (12-08-2020)“…Rotaviruses (RVs) are the most common cause of severe diarrheal disease. To date two rotavirus oral vaccines are licensed: Rotarix and Rotateq. Our aim was to…”
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Calcitonin gene-related peptide antagonists in pregnancy: a disproportionality analysis in VigiBase
Published in Journal of headache and pain (19-01-2024)“…Background Current evidence on the safety of calcitonin gene–related peptide antagonists (CGRP-A) in pregnancy for the treatment of both episodic and chronic…”
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The statistical risk of diagnosing coincidental acquired hemophilia A following anti‐SARS‐CoV‐2 vaccination
Published in Journal of thrombosis and haemostasis (01-09-2021)Get full text
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Reporting of Acute Inflammatory Neuropathies with COVID-19 Vaccines: Subgroup Disproportionality Analyses in VigiBase
Published in Vaccines (Basel) (14-09-2021)“…Since marketing authorization, cases of neuralgic amyotrophy (NA), facial paralysis/Bell’s palsy (FP/BP), and Guillain-Barré syndrome (GBS) were reported with…”
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Reporting of late-onset immune-related adverse events with immune checkpoint inhibitors in VigiBase
Published in Journal for immunotherapy of cancer (03-11-2024)“…Background To date, evidence on late-onset immune-related adverse events (irAEs) with immune checkpoint inhibitors (ICIs) is limited to a small number of…”
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Niacin‐mediated Tace activation ameliorates CMT neuropathies with focal hypermyelination
Published in EMBO molecular medicine (01-12-2016)“…Charcot–Marie–Tooth (CMT) neuropathies are highly heterogeneous disorders caused by mutations in more than 70 genes, with no available treatment. Thus, it is…”
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DDIT4/REDD1/RTP801 is a novel negative regulator of Schwann cell myelination
Published in The Journal of neuroscience (18-09-2013)“…Signals that promote myelination must be tightly modulated to adjust myelin thickness to the axonal diameter. In the peripheral nervous system, axonal…”
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Loss of Fig4 in both Schwann cells and motor neurons contributes to CMT4J neuropathy
Published in Human molecular genetics (15-01-2015)“…Mutations of FIG4 are responsible for Yunis-Varón syndrome, familial epilepsy with polymicrogyria, and Charcot-Marie-Tooth type 4J neuropathy (CMT4J). Although…”
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Kif13b Regulates PNS and CNS Myelination through the Dlg1 Scaffold
Published in PLoS biology (12-04-2016)“…Microtubule-based kinesin motors have many cellular functions, including the transport of a variety of cargos. However, unconventional roles have recently…”
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Sex differences in functional outcomes of intravenous thrombolysis among patients with lacunar stroke
Published in Frontiers in neurology (13-02-2024)“…This study aimed to assess if there are sex differences in the functional outcome of intravenous thrombolysis (IVT) among patients with lacunar stroke (LS)…”
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Self-discharge during treatment for acute recreational drug toxicity: an observational study from emergency departments in seven European countries
Published in International journal of emergency medicine (29-11-2023)“…Background Self-discharge is a risk factor for readmission and excess mortality. We assess the rate of self-discharge from the emergency department (ED) among…”
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Safety of Monoclonal Antibodies Inhibiting PCSK9 in Pregnancy: Disproportionality Analysis in VigiBase
Published in Clinical pharmacology and therapeutics (01-08-2024)“…Safety data on the use of monoclonal antibodies inhibiting proprotein convertase subtilisin/kexin type 9 in pregnancy are scarce. This study queried VigiBase®,…”
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Safety profile of monoclonal antibodies targeting the calcitonin gene-related peptide system in pregnancy: Updated analysis in VigiBase
Published in Cephalalgia (01-04-2023)“…Safety data on the use of migraine preventive monoclonal antibodies targeting the calcitonin gene-related peptide (CGRP) system in pregnancy are limited…”
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Safety of monoclonal antibodies targeting PCSK9 in pregnancy: Analysis of the WHO's global pharmacovigilance database
Published in Neurotoxicology and teratology (01-07-2023)Get full text
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Adverse Event Reporting with Immune Checkpoint Inhibitors in Older Patients: Age Subgroup Disproportionality Analysis in VigiBase
Published in Cancers (06-03-2021)“…Older patients represent a subpopulation of concern for immune checkpoint inhibitor (ICI) toxicity because of changes in the aging immune system and the…”
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Reporting of immune checkpoint inhibitor-associated myocarditis
Published in The Lancet (British edition) (04-08-2018)Get full text
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