Search Results - "Nose, Naoko"
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[18F]FDG-labelled stem cell PET imaging in different route of administrations and multiple animal species
Published in Scientific reports (25-05-2021)“…Stem cell therapy holds great promise for tissue regeneration and cancer treatment, although its efficacy is still inconclusive and requires further…”
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Generative adversarial network-created brain SPECTs of cerebral ischemia are indistinguishable to scans from real patients
Published in Scientific reports (05-11-2022)“…Deep convolutional generative adversarial networks (GAN) allow for creating images from existing databases. We applied a modified light-weight GAN (FastGAN)…”
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Synthesis and Initial Characterization of a Selective, Pseudo‐irreversible Inhibitor of Human Butyrylcholinesterase as PET Tracer
Published in ChemMedChem (06-05-2021)“…The enzyme butyrylcholinesterase (BChE) represents a promising target for imaging probes to potentially enable early diagnosis of neurodegenerative diseases…”
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Initial Evaluation of AF78: a Rationally Designed Fluorine-18-Labelled PET Radiotracer Targeting Norepinephrine Transporter
Published in Molecular imaging and biology (01-06-2020)“…Purpose Taking full advantage of positron emission tomography (PET) technology, fluorine-18-labelled radiotracers targeting norepinephrine transporter (NET)…”
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Synthesis and Initial Characterization of a Reversible, Selective 18F-Labeled Radiotracer for Human Butyrylcholinesterase
Published in Molecular imaging and biology (2021)“…Purpose A neuropathological hallmark of Alzheimer’s disease (AD) is the presence of amyloid-β (Aβ) plaques in the brain, which are observed in a significant…”
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Performance Evaluation of a Preclinical SPECT Scanner with a Collimator Designed for Medium-Sized Animals
Published in Molecular imaging (16-07-2022)“…Background. Equipped with two stationary detectors, a large bore collimator for medium-sized animals has been recently introduced for dedicated preclinical…”
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Metabolic substrate shift in human induced pluripotent stem cells during cardiac differentiation: Functional assessment using in vitro radionuclide uptake assay
Published in International journal of cardiology (15-10-2018)“…Recent developments in cellular reprogramming technology enable the production of virtually unlimited numbers of human induced pluripotent stem cell-derived…”
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Capabilities of multi-pinhole SPECT with two stationary detectors for in vivo rat imaging
Published in Scientific reports (29-10-2020)“…We aimed to investigate the image quality of the U-SPECT5/CT E-Class a micro single-photon emission computed tomography (SPECT) system with two large…”
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In Vivo Functional Assessment of Sodium-Glucose Cotransporters (SGLTs) Using [18F]Me4FDG PET in Rats
Published in Molecular imaging (2022)“…Background. Mediating glucose absorption in the small intestine and renal clearance, sodium glucose cotransporters (SGLTs) have emerged as an attractive…”
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10
Rationalizing the Binding Modes of PET Radiotracers Targeting the Norepinephrine Transporter
Published in Pharmaceutics (17-02-2023)“…A new PET radiotracer F-AF78 showing great potential for clinical application has been reported recently. It belongs to a new generation of…”
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Mutations in DNAJC19 cause altered mitochondrial structure and increased mitochondrial respiration in human iPSC-derived cardiomyocytes
Published in Molecular metabolism (Germany) (01-01-2024)“…Dilated cardiomyopathy with ataxia (DCMA) is an autosomal recessive disorder arising from truncating mutations in DNAJC19, which encodes an inner mitochondrial…”
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Stability of Distribution of F18 Flurpiridaz After Transient Coronary Occlusion in Pigs
Published in JACC. Cardiovascular imaging (01-11-2019)Get full text
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The Number of Frames on ECG-Gated 18F-FDG Small Animal PET Has a Significant Impact on LV Systolic and Diastolic Functional Parameters
Published in Molecular imaging (01-01-2021)“…Objectives. This study is aimed at investigating the impact of frame numbers in preclinical electrocardiogram- (ECG-) gated 18F-fluorodeoxyglucose (18F-FDG)…”
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In vivo tracking transplanted cardiomyocytes derived from human induced pluripotent stem cells using nuclear medicine imaging
Published in Frontiers in cardiovascular medicine (07-09-2023)“…Introduction Transplantation of human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) is a promising treatment for heart failure. Information…”
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Chiral symmetry restoration at high matter density observed in pionic atoms
Published in Nature physics (01-06-2023)“…According to quantum chromodynamics, vacuum is not an empty space, because it is filled with quark–antiquark pairs. The pair has the same quantum numbers as…”
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Subcellular storage and release mode of the novel 18F-labeled sympathetic nerve PET tracer LMI1195
Published in EJNMMI research (06-02-2018)“…Background 18 F- N -[3-bromo-4-(3-fluoro-propoxy)-benzyl]-guanidine ( 18 F-LMI1195) is a new class of PET tracer designed for sympathetic nervous imaging of…”
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The Impact of Ageing on [^sup 11^C]meta-Hydroxyephedrine Uptake in the Rat Heart
Published in The Journal of nuclear medicine (1978) (01-05-2018)“…Objectives: An extensive body of evidence has reported on physiological age-related changes in autonomic nervous system function. The influence of ageing on…”
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Performance Evaluation of a Preclinical SPECT Scanner with a CollimatorDesigned for Medium-Sized Animals
Published in Molecular imaging (01-01-2022)“…Background. Equipped with two stationary detectors, a large borecollimator for medium-sized animals has been recently introduced for dedicatedpreclinical…”
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Stability of Myocardial 18F-flurpiridaz Distribution after Transient Coronary Occlusion in Pigs
Published in The Journal of nuclear medicine (1978) (01-05-2019)“…Background: Flurpiridaz F18 is a promising 18F-labeled myocardial perfusion radiotracer utilising all intrinsic advantages of PET technology. We aimed to…”
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The Impact of Ageing on 11C-Hydroxyephedrine Uptake in the Rat Heart
Published in Scientific reports (24-07-2018)“…We aimed to explore the impact of ageing on 11C-hydroxyephedrine (11C-HED) uptake in the healthy rat heart in a longitudinal setting. To investigate a…”
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