Search Results - "Norwood, P."

Metal–PAH mixtures in the aquatic environment: A review of co-toxic mechanisms leading to more-than-additive outcomes by Gauthier, Patrick T., Norwood, Warren P., Prepas, Ellie E., Pyle, Greg G.

“…Mixtures of metals and polycyclic aromatic hydrocarbons (PAHs) occur ubiquitously in aquatic environments, yet relatively little is known regarding their…”
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The Concurrent and Longitudinal Relationship between Perinatal Sleep Difficulties and Depression in a Large Sample of High-Risk Women in South Africa by Asarnow, L. D., Norwood, P. P., Christodoulou, J., Tomlinson, M., Rotheram-Borus, M. J.

“…Introduction Perinatal depression and sleep difficulties are common among studies conducted in high income countries (HIC). This study examines the…”
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Efficacy and safety of oral semaglutide in patients with type 2 diabetes and moderate renal impairment (PIONEER 5): a placebo-controlled, randomised, phase 3a trial by Mosenzon, Ofri, Blicher, Thalia Marie, Rosenlund, Signe, Eriksson, Jan W, Hels, Ole Holm, Pratley, Richard, Sathyapalan, Thozhukat, Desouza, Cyrus, Abramof, R, Aronoff, S, Barker, B, Benson, M, Biggs, W, Blaze, K, Bogdanski, P, Busch, R, Chandran, S, Chang, A, Chilka, S, Cleland, A, Connery, L, Delgado, B, Desouza, C, Donner, T, Eliasson, K, Eriksson, J, Folkerth, S, Forshaw, K, Frolova, E, Gandy, W, Gatipon, G, Golovach, A, Gonzalez-Orozco, L, Gumprecht, J, Hansen, T K, Hasan, S, Hella, B, Heller, S, Hellgren, M, Hewitt, M, Hietaniemi, S, Hitz, M, Houser, P, Huntley, R, Jackson, R, Jakobsen, P E, Kapoor, A, Kargina, L, Kazakova, E, Khan, K, Klein, E, Knoble, H, Krasnopeeva (Kabachkova), N, Kunitsyna, M, Lawhead, J, Levin, P, Lewy-Alterbaum, L, Lindmark, S, Lindsay, R, Luts, A, Lysenko, T, Madsbad, S, Maxwell, T, Mcknight, J, Metsärinne, K, Milovanova, T, Mosenzon, O, Nabriski, D, Nicol, P, Nieminen, S, Nikkola, A, Norwood, P, O'Donnell, P, Odugbesan, A, Parker, J, Pergaeva, Y, Peskov, A, Plevin, S, Pouzar, J, Pratley, R, Reed, J, Rossing, P, Sathyapalan, T, Sergeeva-Kondrachenko, M, Shaikh, Z, Shamkhalova, M, Shehadeh, N, Shlesinger, Y, Silver, R, Snyder, B, Soufer, J, Strand, J, Sulosaari, S, Tirosh, A, Traylor, H, Uhlenius, N, Vagapova, G, Yanovskaya, M, Zarutskaya, L, Zhdanova, E

“…Oral semaglutide is the first oral glucagon-like peptide-1 (GLP-1) receptor agonist for glycaemic control in patients with type 2 diabetes. Type 2 diabetes is…”
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Association between maternal body mass index during pregnancy, short‐term morbidity, and increased health service costs: a population‐based study by Denison, FC, Norwood, P, Bhattacharya, S, Duffy, A, Mahmood, T, Morris, C, Raja, EA, Norman, JE, Lee, AJ, Scotland, G

“…Objective To investigate the impact of maternal body mass index (BMI, kg/m2) on clinical complications, inpatient admissions, and additional short‐term costs…”
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In Vitro and In Vivo Characterization of the Alkaloid Nuciferine by Farrell, Martilias S, McCorvy, John D, Huang, Xi-Ping, Urban, Daniel J, White, Kate L, Giguere, Patrick M, Doak, Allison K, Bernstein, Alison I, Stout, Kristen A, Park, Su Mi, Rodriguiz, Ramona M, Gray, Bradley W, Hyatt, William S, Norwood, Andrew P, Webster, Kevin A, Gannon, Brenda M, Miller, Gary W, Porter, Joseph H, Shoichet, Brian K, Fantegrossi, William E, Wetsel, William C, Roth, Bryan L

“…The sacred lotus (Nelumbo nucifera) contains many phytochemicals and has a history of human use. To determine which compounds may be responsible for reported…”
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Assessment of the toxicity of mixtures of copper, 9,10-phenanthrenequinone, and phenanthrene to Daphnia magna: Evidence for a reactive oxygen mechanism by Xie, Fangli, Koziar, Stephen A., Lampi, Mark A., Dixon, D. George, Norwood, Warren P., Borgmann, Uwe, Huang, Xiao-Dong, Greenberg, Bruce M.

“…Polycyclic aromatic hydrocarbons and their derivatives are ubiquitous environmental contaminants. They are commonly present in complex mixtures with other…”
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“Doctor my eyes”: A natural experiment on the demand for eye care services by Dickey, H., Ikenwilo, D., Norwood, P., Watson, V., Zangelidis, A.

“…Preventive health care is promoted by many organisations from the World Health Organisation (WHO) to regional and national governments. The degree of…”
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placebo‐controlled trial of exenatide twice‐daily added to thiazolidinediones alone or in combination with metformin by Liutkus, J, Rosas Guzman, J, Norwood, P, Pop, L, Northrup, J, Cao, D, Trautmann, M

“…Aim: To test the hypothesis that glycaemic control with exenatide added to thiazolidinediones (TZDs) with or without metformin was superior to placebo…”
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Chronic toxicity of arsenic, cobalt, chromium and manganese to Hyalella azteca in relation to exposure and bioaccumulation by Norwood, W.P., Borgmann, U., Dixon, D.G.

“…Chronic toxicity of As, Co, Cr and Mn to Hyalella azteca can be described using a saturation-based mortality model relative to total-body or water metal…”
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Re-evaluation of metal bioaccumulation and chronic toxicity in Hyalella azteca using saturation curves and the biotic ligand model by Borgmann, U., Norwood, W.P., Dixon, D.G.

“…Bioaccumulation by Hyalella of all metals studied so far in our laboratory was re-evaluated to determine if the data could be explained satisfactorily using…”
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Pharmacokinetic and pharmacodynamic assessment of a five‐probe metabolic cocktail for CYPs 1A2, 3A4, 2C9, 2D6 and 2E1 by Blakey, G. E., Lockton, J. A., Perrett, J., Norwood, P., Russell, M., Aherne, Z., Plume, J.

“…Aims  The primary objectives of the present study were to establish whether there was a pharmacokinetic or pharmacodynamic interaction between the probe drugs…”
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Interactive effects of metals in mixtures on bioaccumulation in the amphipod Hyalella azteca by Norwood, W.P., Borgmann, U., Dixon, D.G.

“…Mixtures were produced of “equi-toxic” concentrations of 10 elements at the 4-week LC25 for Hyalella azteca. Bioaccumulation was determined in 1-week…”
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Effects of Metal Mixtures on Aquatic Biota: A Review of Observations and Methods by Norwood, W.P., Borgmann, U., Dixon, D.G., Wallace, A.

“…A brief review of the historical development of metal mixture interaction analyses is presented. The two major classifications of mixture models are outlined,…”
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Saturation models of arsenic, cobalt, chromium and manganese bioaccumulation by Hyalella azteca by Norwood, W.P., Borgmann, U., Dixon, D.G.

“…Bioaccumulation of As, Co, Cr and Mn by the benthic amphipod Hyalella azteca in Burlington City tap (Lake Ontario) water was measured in 4-week tests…”
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Efficacy and safety of the dipeptidyl peptidase-4 inhibitor PF-734200 added to metformin in Type 2 diabetes by Rosenstock, J., Lewin, A. J., Norwood, P., Somayaji, V., Nguyen, T. T., Teeter, J. G., Johnson, S. L., Dai, H., Terra, S. G.

“…Diabet. Med. 28, 464–469 (2011) Aims  PF‐734200 is a potent and selective oral dipeptidyl peptidase‐4 (DPP‐4) inhibitor. This study assessed the efficacy and…”
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Effects of inhaled human insulin on airway lining fluid composition in adults with diabetes by Liu, M. C, Riese, R. J, Van Gundy, K, Norwood, P, Sullivan, B. E, Schwartz, P. F, Teeter, J. G

“…Inhaled human insulin (Exubera (human insulin of rDNA origin) Inhalation Powder) causes small, early and reversible changes in pulmonary function in subjects…”
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Long-term effects of an early-life exposure of fathead minnows to sediments containing bitumen. Part II: Behaviour, reproduction, and gonad histopathology by Vignet, C., Frank, R.A., Yang, C., Shires, K., Bree, M., Sullivan, C., Norwood, W.P., Hewitt, L.M., McMaster, M.E., Parrott, J.L.

“…The oil sands area of northern Alberta has river sediments that contain natural bitumen. Eggs and fish in these rivers may be exposed to bitumen-related…”
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Summary of breakout session f: facility and equipment decontamination strategies by Norwood, Laurie P, Suvarna, Kalavati

“…CONFERENCE PROCEEDING Proceedings of the PDA/FDA Adventitious Viruses in Biologics: Detection and Mitigation Strategies Workshop in Bethesda, MD, USA; December…”
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Toxicity and bioaccumulation of thallium in Hyalella azteca, with comparison to other metals and prediction of environmental impact by Borgmann, U, Cheam, V, Norwood, W.P, Lechner, J

“…Thallium (Tl) is an extremely toxic but little studied metal. For Hyalella azteca exposed in Lake Ontario water, a 25% reduction in survival (the LC 25)…”
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Metal–Polycyclic Aromatic Hydrocarbon Mixture Toxicity in Hyalella azteca. 2. Metal Accumulation and Oxidative Stress as Interactive Co-toxic Mechanisms by Gauthier, Patrick T, Norwood, Warren P, Prepas, Ellie E, Pyle, Greg G

“…Mixtures of metals and polycyclic aromatic hydrocarbons (PAHs) are commonly found in aquatic environments. Emerging reports have identified that…”
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