Search Results - "Norton, William H"

The potential for adverse effects in fish exposed to antidepressants in the aquatic environment by Gould, Sophie L, Winter, Matthew J, Norton, William H. J, Tyler, Charles R

“…Antidepressants are one of the most commonly prescribed pharmaceutical classes for the treatment of psychiatric conditions. They act via modulation of brain…”
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Transcriptomic underpinnings of high and low mirror aggression zebrafish behaviours by Reichmann, Florian, Pilic, Johannes, Trajanoski, Slave, Norton, William H J

“…Aggression is an adaptive behaviour that animals use to protect offspring, defend themselves and obtain resources. Zebrafish, like many other animals, are not…”
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The three-spined stickleback as a model for behavioural neuroscience by Norton, William H J, Gutiérrez, Héctor Carreño

“…The three-spined stickleback (Gasterosteus aculeatus) is a small teleost fish that is ubiquitous across the Northern Hemisphere. Among the behaviours that have…”
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A novel portable flip-phone based visual behaviour assay for zebrafish by Rodwell, Vanessa, Birchall, Annabel, Yoon, Ha-Jun, Kuht, Helen J., Norton, William H. J., Thomas, Mervyn G.

“…The optokinetic reflex (OKR) serves as a vital index for visual system development in early life, commonly observed within the first six months post-birth in…”
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Inter-individual and inter-strain variations in zebrafish locomotor ontogeny by Lange, Merlin, Neuzeret, Frederic, Fabreges, Benoit, Froc, Cynthia, Bedu, Sebastien, Bally-Cuif, Laure, Norton, William H J

“…Zebrafish exhibit remarkable alterations in behaviour and morphology as they develop from early larval stages to mature adults. In this study we compare the…”
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Novel non-stimulants rescue hyperactive phenotype in an adgrl3.1 mutant zebrafish model of ADHD by Sveinsdóttir, Hildur Sóley, Christensen, Christian, Þorsteinsson, Haraldur, Lavalou, Perrine, Parker, Matthew O, Shkumatava, Alena, Norton, William H J, Andriambeloson, Emile, Wagner, Stéphanie, Karlsson, Karl Ægir

“…ADHD is a highly prevalent neurodevelopmental disorder. The first-line therapeutic for ADHD, methylphenidate, can cause serious side effects including weight…”
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Correction: The three-spined stickleback as a model for behavioural neuroscience by Norton, William H J, Carreño Gutiérrez, Héctor

“…[This corrects the article DOI: 10.1371/journal.pone.0213320.]…”
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Deficiency of the ywhaz gene, involved in neurodevelopmental disorders, alters brain activity and behaviour in zebrafish by Antón-Galindo, Ester, Dalla Vecchia, Elisa, Orlandi, Javier G., Castro, Gustavo, Gualda, Emilio J., Young, Andrew M. J., Guasch-Piqueras, Marc, Arenas, Concepció, Herrera-Úbeda, Carlos, Garcia-Fernàndez, Jordi, Aguado, Fernando, Loza-Alvarez, Pablo, Cormand, Bru, Norton, William H. J., Fernàndez-Castillo, Noèlia

“…Genetic variants in YWHAZ contribute to psychiatric disorders such as autism spectrum disorder and schizophrenia, and have been related to an impaired…”
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Endothelin neurotransmitter signalling controls zebrafish social behaviour by Carreño Gutiérrez, Héctor, Colanesi, Sarah, Cooper, Ben, Reichmann, Florian, Young, Andrew M. J., Kelsh, Robert N., Norton, William H. J.

“…The formation of social groups is an adaptive behaviour that can provide protection from predators, improve foraging and facilitate social learning. However,…”
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Skin swabbing is a refined technique to collect DNA from model fish species by Tilley, Ceinwen A., Carreño Gutierrez, Hector, Sebire, Marion, Obasaju, Oluwapelumi, Reichmann, Florian, Katsiadaki, Ioanna, Barber, Iain, Norton, William H. J.

“…Model fish species such as sticklebacks and zebrafish are frequently used in studies that require DNA to be collected from live animals. This is typically…”
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adgrl3.1-deficient zebrafish show noradrenaline-mediated externalizing behaviors, and altered expression of externalizing disorder-candidate genes, suggesting functional targets for treatment by Fontana, Barbara D., Reichmann, Florian, Tilley, Ceinwen A., Lavlou, Perrine, Shkumatava, Alena, Alnassar, Nancy, Hillman, Courtney, Karlsson, Karl Ægir, Norton, William H. J., Parker, Matthew O.

“…Externalizing disorders (ED) are a cause of concern for public health, and their high heritability makes genetic risk factors a priority for research. Adhesion…”
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Pleiotropic contribution of rbfox1 to psychiatric and neurodevelopmental phenotypes in two zebrafish models by Antón-Galindo, Ester, Adel, Maja R., García-González, Judit, Leggieri, Adele, López-Blanch, Laura, Irimia, Manuel, Norton, William H. J., Brennan, Caroline H., Fernàndez-Castillo, Noèlia, Cormand, Bru

“…RBFOX1 is a highly pleiotropic gene that contributes to several psychiatric and neurodevelopmental disorders. Both rare and common variants in RBFOX1 have been…”
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Zebrafish Optokinetic Reflex: Minimal Reporting Guidelines and Recommendations by Rodwell, Vanessa, Patil, Manjiri, Kuht, Helen J, Neuhauss, Stephan C F, Norton, William H J, Thomas, Mervyn G

“…Optokinetic reflex (OKR) assays in zebrafish models are a valuable tool for studying a diverse range of ophthalmological and neurological conditions. Despite…”
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Using zebrafish to uncover the genetic and neural basis of aggression, a frequent comorbid symptom of psychiatric disorders by Jones, Lauren J, Norton, William H J

“…Aggression is an important adaptive behavior that can be used to monopolize resources such as mates or food, acquire and defend territory and establish…”
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Dynamic Fgf signaling couples morphogenesis and migration in the zebrafish lateral line primordium by Lecaudey, Virginie, Cakan-Akdogan, Gulcin, Norton, William H. J., Gilmour, Darren

“…The collective migration of cells in the form of cohesive tissues is a hallmark of both morphogenesis and repair. The extrinsic cues that direct these complex…”
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Genetic and environmental modulation of neurodevelopmental disorders: translational insights from labs to beds by Homberg, Judith R, Kyzar, Evan J, Scattoni, Maria Luisa, Norton, William H, Pittman, Julian, Gaikwad, Siddharth, Nguyen, Michael, Poudel, Manoj K, Ullmann, Jeremy F.P, Diamond, David M, Kaluyeva, Aleksandra A, Parker, Matthew O, Brown, Richard E, Song, Cai, Gainetdinov, Raul R, Gottesman, Irving I, Kalueff, Allan V

“…Highlights • Neurodevelopmental disorders (NDDs) are severely debilitating neuropsychiatric illnesses. • NDDs are caused by aberrant brain development, and…”
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Modulation of Fgfr1a signaling in zebrafish reveals a genetic basis for the aggression-boldness syndrome by Norton, William H J, Stumpenhorst, Katharina, Faus-Kessler, Theresa, Folchert, Anja, Rohner, Nicolas, Harris, Matthew P, Callebert, Jacques, Bally-Cuif, Laure

“…Behavioral syndromes are suites of two or more behaviors that correlate across environmental contexts. The aggression-boldness syndrome links aggression,…”
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Aggression in non-human vertebrates: Genetic mechanisms and molecular pathways by Freudenberg, Florian, Carreño Gutierrez, Hector, Post, Antonia M., Reif, Andreas, Norton, William H. J.

“…Aggression is an adaptive behavioral trait that is important for the establishment of social hierarchies and competition for mating partners, food, and…”
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HSPG synthesis by zebrafish Ext2 and Extl3 is required for Fgf10 signalling during limb development by Norton, William H J, Ledin, Johan, Grandel, Heiner, Neumann, Carl J

“…Heparan sulphate proteoglycans (HSPGs) are known to be crucial for signalling by the secreted Wnt, Hedgehog, Bmp and Fgf proteins during invertebrate…”
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The Visually Mediated Social Preference Test: A Novel Technique to Measure Social Behavior and Behavioral Disturbances in Zebrafish by Norton, William H J, Manceau, Line, Reichmann, Florian

“…Zebrafish are an emerging model in behavioral neuroscience. They display a wide range of measurable behaviors such as locomotion, aggression, anxiety, learning…”
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