Search Results - "Northeved, Helle"

In vivo toxicity of cationic micelles and liposomes by Knudsen, Kristina Bram, PhD, Northeved, Helle, DVM, PhD, Kumar EK, Pramod, PhD, Permin, Anders, DVM, PhD, Gjetting, Torben, PhD, Andresen, Thomas L., PhD, Larsen, Steen, DVM, PhD, Wegener, Karen Malene, DVM, PhD, Lykkesfeldt, Jens, PhD, DSc, Jantzen, Kim, MSc, Loft, Steffen, MD, Møller, Peter, PhD, Roursgaard, Martin, PhD

“…Abstract This study investigated toxicity of nanocarriers comprised of cationic polymer and lipid components often used in gene and drug delivery, formulated…”
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In vitro toxicity of cationic micelles and liposomes in cultured human hepatocyte (HepG2) and lung epithelial (A549) cell lines by Roursgaard, Martin, Knudsen, Kristina Bram, Northeved, Helle, Persson, Mikael, Christensen, Tina, Kumar, Pramod E K, Permin, Anders, Andresen, Thomas L, Gjetting, Torben, Lykkesfeldt, Jens, Vesterdal, Lise K, Loft, Steffen, Møller, Peter

“…The aim of this study was to compare the effects of cationic micelle and liposome drug delivery systems on liver and lung cells in a toxicological in vitro…”
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Dopamine and prolactin interaction in rat developmental and reproductive toxicity studies by Zhuang, Qikun, Rasmussen, Allan D., Bernholm, Karina, Northeved, Helle

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Legacy data sharing to improve drug safety assessment: the eTOX project by Sanz, Ferran, Pognan, François, Steger-Hartmann, Thomas, Díaz, Carlos, Cases, Montserrat, Pastor, Manuel, Marc, Philippe, Wichard, Joerg, Briggs, Katharine, Watson, David K., Kleinöder, Thomas, Yang, Chihae, Amberg, Alexander, Beaumont, Maria, Brookes, Anthony J., Brunak, Søren, Cronin, Mark T. D., Ecker, Gerhard F., Escher, Sylvia, Greene, Nigel, Guzmán, Antonio, Hersey, Anne, Jacques, Pascale, Lammens, Lieve, Mestres, Jordi, Muster, Wolfgang, Northeved, Helle, Pinches, Marc, Saiz, Javier, Sajot, Nicolas, Valencia, Alfonso, van der Lei, Johan, Vermeulen, Nico P. E., Vock, Esther, Wolber, Gerhard, Zamora, Ismael

“…The sharing of legacy preclinical safety data among pharmaceutical companies and its integration with other information sources offers unprecedented…”
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Differential toxicological response to positively and negatively charged nanoparticles in the rat brain by Knudsen, Kristina Bram, Northeved, Helle, EK, Pramod Kumar, Permin, Anders, Andresen, Thomas L., Larsen, Steen, Wegener, Karen Malene, Lam, Henrik Rye, Lykkesfeldt, Jens

“…Abstract We investigated the potential for systemic and local toxicity after administration of empty nanosized anionic and cationic PEGylated-micelles and…”
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Accelerating Global Deletion of the Abnormal Toxicity Test for vaccines and biologicals. Planning common next steps. A workshop Report by Viviani, Laura, Reid, Kirsty, Gastineau, Thierry, Milne, Catherine, Smith, Dean, Levis, Robin, Lei, Dianliang, van Ooij, Mark, Gilbert, Philippe Alexandre, Vandeputte, Joris, Xie, Jianxun, Madhuri, Leena, Shaid, Shahjahan, Kubiak, Vaughn, Suri, Rajinder, Mizukami, Takuo, Shirasaki, Yoshihisa, Li, Xiantang, Zhou, Ying-Ying, Trapkova, Alla, Goel, Sunil, Prakash, Jai, Subagio, Amrullah Aninditio, Suwarni, Eniek, Jung, Kyung Jin, Sanyal, Gautam, Das, Pradip, Coppens, Emmanuelle, Wright, David, Peng, Zhechu, Northeved, Helle, Jungbäck, Carmen, Kirpitchenok, Tatiana, Del Pace, Lorenzo, Seo, Borami, Poojary, Brinda, Ottoni, Antoniana

“…This online workshop Accelerating Global Deletion of the Abnormal Toxicity Test for vaccines and biologicals. Planning common next steps was organized on…”
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Embryo-fetal developmental toxicity with AAX in rat and zebrafish by Zhuang, Qikun, Albrechtsen, Sten, Rasmussen, Allan D., Northeved, Helle

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Biodistribution of rhodamine B fluorescence-labeled cationic nanoparticles in rats by Knudsen, Kristina Bram, Northeved, Helle, Gjetting, Torben, Permin, Anders, Andresen, Thomas L., Wegener, Karen Malene, Lam, Henrik Rye, Lykkesfeldt, Jens

“…We investigated the biodistribution following the administration of nanosized (about 50 and 90 nm) cationic ( ζ : +30 and +50 mV) micelles and liposomes…”
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