Search Results - "Norris, Virginia"
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CCL20 neutralization by a monoclonal antibody in healthy subjects selectively inhibits recruitment of CCR6+ cells in an experimental suction blister
Published in British journal of clinical pharmacology (01-09-2017)“…Aims GSK3050002, a humanized IgG1κ antibody with high binding affinity to human CCL20, was administered in a first‐in‐human study to evaluate safety,…”
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2
Stigma, Help-Seeking Attitudes, and Use of Psychotherapy in Veterans With Diagnoses of Posttraumatic Stress Disorder
Published in The journal of nervous and mental disease (01-11-2011)“…Survey and medical record data from 482 Veterans Affairs (VA) patients who recently received diagnoses of posttraumatic stress disorder (PTSD) were examined to…”
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3
Identification of p.A684V missense mutation in the WFS1 gene as a frequent cause of autosomal dominant optic atrophy and hearing impairment
Published in American journal of medical genetics. Part A (01-06-2011)“…Optic atrophy (OA) and sensorineural hearing loss (SNHL) are key abnormalities in several syndromes, including the recessively inherited Wolfram syndrome,…”
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4
Patient Perspectives on Breast Cancer Treatment Plan and Summary Documents in Community Oncology Care: A Pilot Program
Published in Cancer (2013)“…Although the routine use of treatment plans and summaries (TPSs) has been recommended to improve the quality of cancer care, limited data exist about their…”
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5
The Changing Age of Individuals Seeking Presymptomatic Genetic Testing for Huntington Disease
Published in Journal of genetic counseling (01-09-2018)“…Huntington disease (HD) is a progressive neurodegenerative disorder. Presymptomatic genetic testing allows at-risk individuals to clarify their risk status…”
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Etiology of unilateral hearing loss in a national hereditary deafness repository
Published in American journal of otolaryngology (01-09-2012)“…Abstract Purpose The aim of this study was to characterize the genetic, audiologic, and epidemiologic characteristics of unilateral hearing loss (HL) in a…”
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Does Universal Newborn Hearing Screening Identify All Children with GJB2 (Connexin 26) Deafness? Penetrance of GJB2 Deafness
Published in Ear and hearing (01-12-2006)“…OBJECTIVE:Deafness is the most common neurosensory defect at birth, and GJB2 (connexin 26) mutations are the most frequent genetic cause of hearing loss in…”
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Implementing a breast cancer registry and treatment plan/summary program in clinical practice: A pilot program
Published in Cancer (01-01-2013)“…BACKGROUND: There is a need to better measure and improve the quality of oncology care and improve communication with patients and other providers. The…”
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A Comparative Analysis of the Genetic Epidemiology of Deafness in the United States in Two Sets of Pedigrees Collected More than a Century Apart
Published in American journal of human genetics (01-08-2008)“…In 1898, E.A. Fay published an analysis of nearly 5000 marriages among deaf individuals in America collected during the 19th century. Each pedigree included…”
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10
Vestibular dysfunction in DFNB1 deafness
Published in American journal of medical genetics. Part A (01-05-2011)“…Mutations of GJB2 and GJB6 (connexin‐26 and 30) at the DFNB1 locus are the most common cause of autosomal recessive, nonsyndromic deafness. Despite their…”
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Impact of genetic advances and testing for hearing loss: Results from a national consumer survey
Published in American journal of medical genetics. Part A (01-06-2009)“…Hearing loss is a common neuro‐sensory deficit; nearly 50% of children with hearing loss have a genetic etiology. With the discovery of 40 genes and more than…”
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Fitness Among Individuals with Early Childhood Deafness: Studies in Alumni Families from Gallaudet University
Published in Annals of human genetics (01-01-2010)“…Summary The genetic fitness of an individual is influenced by their phenotype, genotype and family and social structure of the population in which they live…”
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Provision of Genetic Services for Hearing Loss: Results from a National Survey and Comparison to Insights Obtained from Previous Focus Group Discussions
Published in Journal of genetic counseling (01-12-2009)“…Hearing loss is a common sensory deficit and more than 50% of affected individuals have a genetic etiology. The discovery of 40 genes and more than 100 loci…”
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14
Vilanterol trifenatate, a novel inhaled long-acting beta2 adrenoceptor agonist, is well tolerated in healthy subjects and demonstrates prolonged bronchodilation in subjects with asthma and COPD
Published in Pulmonary pharmacology & therapeutics (01-04-2013)“…Abstract Vilanterol (VI; GW642444M) is a novel inhaled long-acting β2-agonist with inherent 24 h activity in vitro in development as a combination with the…”
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Bronchodilation and safety of supratherapeutic doses of salbutamol or ipratropium bromide added to single dose GSK961081 in patients with moderate to severe COPD
Published in Pulmonary pharmacology & therapeutics (01-10-2013)“…Abstract Background There are few data on the bronchodilatory effects of adding short-acting bronchodilators (SABA) to maintenance, long-acting bronchodilator…”
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Use of Propranolol Blockade to Explore the Pharmacology of GSK961081, a Bi-Functional Bronchodilator, in Healthy Volunteers: Results from Two Randomized Trials
Published in Drugs in R&D (01-12-2014)“…Purpose The objective of this study was to explore the pharmacology of GSK961081, a bi-functional bronchodilator, in healthy volunteers. Methods Two…”
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"Drive-by English": Teaching College English to High School Students via Interactive TV
Published in Teaching English in the two-year college (01-05-2005)“…This paper outlines challenges in and essential criteria for the success of dual-credit or concurrent-enrollment writing and literature courses delivered via…”
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Safety and efficacy of pridopidine in patients with Huntington's disease (PRIDE-HD): a phase 2, randomised, placebo-controlled, multicentre, dose-ranging study
Published in Lancet neurology (01-02-2019)“…Previous trials have shown that pridopidine might reduce motor impairment in patients with Huntington's disease. The aim of this study was to ascertain whether…”
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Effect of Inhaled Interferon Beta-1a on Carbon Monoxide Transfer Factor in Healthy Volunteers
Published in Journal of interferon & cytokine research (01-02-2016)“…Interferon beta-1a (IFNβ-1a) 30 μg weekly by intramuscular (IM) injection is used to treat relapsing forms of multiple sclerosis. We assessed if it can be…”
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Pharmacodynamics of GSK961081, a bi-functional molecule, in patients with COPD
Published in Pulmonary pharmacology & therapeutics (01-10-2013)“…Abstract GSK961081 is an inhaled bi-functional molecule with both muscarinic antagonism and β2 -agonism (MABA) properties. This randomised, double-blind,…”
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