Search Results - "Norris, Gregory H"

Dietary and Endogenous Sphingolipid Metabolism in Chronic Inflammation by Norris, Gregory H, Blesso, Christopher N

“…Chronic inflammation is a common underlying factor in many major metabolic diseases afflicting Western societies. Sphingolipid metabolism is pivotal in the…”
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Protective properties of milk sphingomyelin against dysfunctional lipid metabolism, gut dysbiosis, and inflammation by Norris, Gregory H., Milard, Marine, Michalski, Marie-Caroline, Blesso, Christopher N.

“…The identification of natural bioactive compounds aimed at promoting optimal gut health and improving lipid metabolism is paramount in the prevention of…”
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Dietary sphingomyelin attenuates hepatic steatosis and adipose tissue inflammation in high-fat-diet-induced obese mice by Norris, Gregory H., Porter, Caitlin M., Jiang, Christina, Millar, Courtney L., Blesso, Christopher N.

“…Western-type diets can induce obesity and related conditions such as dyslipidemia, insulin resistance and hepatic steatosis. We evaluated the effects of milk…”
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Dietary sphingolipids: potential for management of dyslipidemia and nonalcoholic fatty liver disease by Norris, Gregory H., Blesso, Christopher N.

“…The development of therapeutic approaches aimed at reducing inflammation, improving lipid metabolism, and preventing nonalcoholic fatty liver disease holds…”
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Cow's milk polar lipids reduce atherogenic lipoprotein cholesterol, modulate gut microbiota and attenuate atherosclerosis development in LDL-receptor knockout mice fed a Western-type diet by Millar, Courtney L., Jiang, Christina, Norris, Gregory H., Garcia, Chelsea, Seibel, Samantha, Anto, Liya, Lee, Ji-Young, Blesso, Christopher N.

“…Milk sphingomyelin (SM), a polar lipid (PL) component of milk fat globule membranes, is protective against dyslipidemia. However, it is unclear whether…”
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Novel computational biology modeling system can accurately forecast response to neoadjuvant therapy in early breast cancer by Peterson, Joseph R, Cole, John A, Pfeiffer, John R, Norris, Gregory H, Zhang, Yuhan, Lopez-Ramos, Dorys, Pandey, Tushar, Biancalana, Matthew, Esslinger, Hope R, Antony, Anuja K, Takiar, Vinita

“…Generalizable population-based studies are unable to account for individual tumor heterogeneity that contributes to variability in a patient's response to…”
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Moringa Leaves Prevent Hepatic Lipid Accumulation and Inflammation in Guinea Pigs by Reducing the Expression of Genes Involved in Lipid Metabolism by Almatrafi, Manal Mused, Vergara-Jimenez, Marcela, Murillo, Ana Gabriela, Norris, Gregory H, Blesso, Christopher N, Fernandez, Maria Luz

“…To investigate the mechanisms by which leaves (ML) modulate hepatic lipids, guinea pigs were allocated to either control (0% ML), 10% Low Moringa (LM) or 15%…”
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Dietary Egg Sphingomyelin Prevents Aortic Root Plaque Accumulation in Apolipoprotein-E Knockout Mice by Millar, Courtney L, Norris, Gregory H, Vitols, Addison, Garcia, Chelsea, Seibel, Samantha, Anto, Liya, Blesso, Christopher N

“…Western-style diets have been linked with dyslipidemia and inflammation, two well-known risk factors associated with cardiovascular disease (CVD). Dietary…”
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Dietary Milk Sphingomyelin Reduces Systemic Inflammation in Diet-Induced Obese Mice and Inhibits LPS Activity in Macrophages by Norris, Gregory, Porter, Caitlin, Jiang, Christina, Blesso, Christopher

“…High-fat diets (HFD) increase lipopolysaccharide (LPS) activity in the blood and may contribute to systemic inflammation with obesity. We hypothesized that…”
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Intake of up to 3 Eggs per Day Is Associated with Changes in HDL Function and Increased Plasma Antioxidants in Healthy, Young Adults by DiMarco, Diana M, Norris, Gregory H, Millar, Courtney L, Blesso, Christopher N, Fernandez, Maria Luz

“…HDL function may be more important than HDL concentration in determining risk for cardiovascular disease. In addition, HDL is a carrier of carotenoids and…”
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Black elderberry extract attenuates inflammation and metabolic dysfunction in diet-induced obese mice by Farrell, Nicholas J., Norris, Gregory H., Ryan, Julia, Porter, Caitlin M., Jiang, Christina, Blesso, Christopher N.

“…Dietary anthocyanins have been shown to reduce inflammation in animal models and may ameliorate obesity-related complications. Black elderberry is one of the…”
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Compared with Powdered Lutein, a Lutein Nanoemulsion Increases Plasma and Liver Lutein, Protects against Hepatic Steatosis, and Affects Lipoprotein Metabolism in Guinea Pigs by Murillo, Ana Gabriela, Aguilar, David, Norris, Gregory H, DiMarco, Diana M, Missimer, Amanda, Hu, Siqi, Smyth, Joan A, Gannon, Sarah, Blesso, Christopher N, Luo, Yangchao, Fernandez, Maria Luz

“…It is not clear how oil-in-water nanoemulsions of lutein may affect bioavailability and consequently alter lipoprotein metabolism, oxidative stress, and…”
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Long‐Term Supplementation of Black Elderberries Promotes Hyperlipidemia, but Reduces Liver Inflammation and Improves HDL Function and Atherosclerotic Plaque Stability in Apolipoprotein E‐Knockout Mice by Millar, Courtney L., Norris, Gregory H., Jiang, Christina, Kry, James, Vitols, Addison, Garcia, Chelsea, Park, Young‐Ki, Lee, Ji‐Young, Blesso, Christopher N.

“…Scope HDL particles are protective against atherosclerosis, but may become dysfunctional during inflammation and chronic disease progression. Anthocyanin‐rich…”
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Milk sphingomyelin improves lipid metabolism and alters gut microbiota in high fat diet-fed mice by Norris, Gregory H., Jiang, Christina, Ryan, Julia, Porter, Caitlin M., Blesso, Christopher N.

“…High dietary fat intake can cause elevated serum and hepatic lipids, as well as contribute to gut dysbiosis, intestinal barrier dysfunction and increased…”
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Hepatocyte-Specific Loss of PPARγ Protects Mice From NASH and Increases the Therapeutic Effects of Rosiglitazone in the Liver by Lee, Samuel M., Pusec, Carolina M., Norris, Gregory H., De Jesus, Adam, Diaz-Ruiz, Alberto, Muratalla, Jose, Sarmento-Cabral, Andre, Guzman, Grace, Layden, Brian T., Cordoba-Chacon, Jose

“…Nonalcoholic steatohepatitis (NASH) is commonly observed in patients with type 2 diabetes, and thiazolidinediones (TZD) are considered a potential therapy for…”
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Effects of Freeze-Dried Grape Powder on High-Density Lipoprotein Function in Adults with Metabolic Syndrome: A Randomized Controlled Pilot Study by Millar, Courtney L, Duclos, Quinn, Garcia, Chelsea, Norris, Gregory H, Lemos, Bruno S, DiMarco, Diana M, Fernandez, Maria Luz, Blesso, Christopher N

“…High-density lipoprotein (HDL) particles are protective against atherosclerosis. However, HDL function is impaired in metabolic syndrome (MetS) due to…”
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Compared to an Oatmeal Breakfast, Two Eggs/Day Increased Plasma Carotenoids and Choline without Increasing Trimethyl Amine N-Oxide Concentrations by Missimer, Amanda, Fernandez, Maria Luz, DiMarco, Diana M., Norris, Gregory H., Blesso, Christopher N., Murillo, Ana Gabriela, Vergara-Jimenez, Marcela, Lemos, Bruno S., Medina-Vera, Isabel, Malysheva, Olga V., Caudill, Marie A.

“…Background: Habitual consumption of eggs has been hypothesized to positively modify biomarkers of cardiovascular disease risk through proposed antioxidant…”
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Effects of Sphingomyelin‐rich Beta Serum on Lipid Metabolism in High Fat Diet‐fed Mice by Norris, Gregory H, Blesso, Christopher N

“…Abstract only Dietary phospholipids are a potential source of bioactive lipids that may impact inflammation and lipid metabolism. One such dietary…”
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Dietary Sphingomyelin Attenuates Inflammation and Metabolic Dysfunction in Diet‐ Induced Obese Mice by Norris, Gregory H, Porter, Caitlin M, Jiang, Christina, Blesso, Christopher

“…Abstract only Current evidence indicates that dietary sphingomyelin (SM) is lipid‐lowering and anti‐inflammatory, although its potential to prevent chronic…”
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Black Elderberry Extract Improves Serum HDL‐cholesterol and Paraoxonase‐1 Activity in Atherosclerosis‐Prone Mice by Millar, Courtney L., Winter, Heather, Georgelos, Jamie, Norris, Gregory H, Park, Young‐Ki, Blesso, Christopher N

“…Abstract only Cardiovascular disease (CVD) is one of the most prevalent non‐communicable diseases in the United States, claiming upwards of 600,000 lives per…”
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