Search Results - "Norris, Andrew J"

Ionizing Radiation Activates the Nrf2 Antioxidant Response by MCDONALD, J. Tyson, KIM, Kwanghee, MCBRIDE, William H, NORRIS, Andrew J, VLASHI, Erina, PHILLIPS, Tiffany M, LAGADEC, Chann, DONNA, Lorenza Della, RATIKAN, Josephine, SZELAG, Heather, HLATKY, Lynn

“…The transcription factor NF-E2-related factor 2 (Nrf2) binds the antioxidant DNA response element (ARE) to activate important cellular cytoprotective defense…”
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Uninvited and unwelcome: The SS Appam and the US law of neutrality by Norris, Andrew J

“…On 15 January 1916, the British steamer Appam was captured near the Madeiras by the German raider Moewe. British mystification regarding her disappearance was…”
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4-(Nitrophenylsulfonyl)piperazines mitigate radiation damage to multiple tissues by Micewicz, Ewa D, Kim, Kwanghee, Iwamoto, Keisuke S, Ratikan, Josephine A, Cheng, Genhong, Boxx, Gayle M, Damoiseaux, Robert D, Whitelegge, Julian P, Ruchala, Piotr, Nguyen, Christine, Purbey, Prabhat, Loo, Joseph, Deng, Gang, Jung, Michael E, Sayre, James W, Norris, Andrew J, Schaue, Dörthe, McBride, William H

“…Our ability to use ionizing radiation as an energy source, as a therapeutic agent, and, unfortunately, as a weapon, has evolved tremendously over the past 120…”
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Classes of Drugs that Mitigate Radiation Syndromes by Micewicz, Ewa D, Damoiseaux, Robert D, Deng, Gang, Gomez, Adrian, Iwamoto, Keisuke S, Jung, Michael E, Nguyen, Christine, Norris, Andrew J, Ratikan, Josephine A, Ruchala, Piotr, Sayre, James W, Schaue, Dörthe, Whitelegge, Julian P, McBride, William H

“…We previously reported several vignettes on types and classes of drugs able to mitigate acute and, in at least one case, late radiation syndromes in mice. Most…”
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Nitroxyl inhibits breast tumor growth and angiogenesis by Norris, Andrew J., Sartippour, Maryam R., Lu, Ming, Park, Taylor, Rao, Jian Yu, Jackson, Matthew I., Fukuto, Jon M., Brooks, Mai N.

“…Nitroxyl (HNO) can inhibit the glycolytic enzyme glyceraldehyde 3‐phosphate dehydrogenase (GAPDH). Because of the importance of glycolysis in many malignant…”
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High-Throughput Screening Identifies Two Classes of Antibiotics as Radioprotectors: Tetracyclines and Fluoroquinolones by KIM, Kwanghee, POLLARD, Julianne M, PRICE, Brendan D, GATTI, Richard A, MCBRIDE, William H, NORRIS, Andrew J, MCDONALD, J. Tyson, YINGLI SUN, MICEWICZ, Ewa, PETTIJOHN, Kelly, DAMOISEAUX, Robert, IWAMOTO, Keisuke S, SAYRE, James W

“…Purpose: Discovery of agents that protect or mitigate normal tissue from radiation injury during radiotherapy, accidents, or terrorist attacks is of…”
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Borate-nucleotide complex formation depends on charge and phosphorylation state by Kim, Danny H., Faull, Kym F., Norris, Andrew J., Eckhert, Curtis D.

“…Flow injection analysis with electrospray ionization mass spectrometry was used to investigate borate–nucleotide complex formation. Solutions containing 100 µM…”
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Targeted inhibition of EG-1 blocks breast tumor growth by Lu, Ming, Sartippour, Maryam R., Zhang, Liping, Norris, Andrew J., Brooks, Mai N.

“…EG-1 is a gene product that is significantly elevated in human breast cancer tissues. Previously, we have shown that EG-1 overexpression stimulates cellular…”
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Analysis of Enzyme Kinetics Using Electrospray Ionization Mass Spectrometry and Multiple Reaction Monitoring:  Fucosyltransferase V by Norris, Andrew J, Whitelegge, Julian P, Faull, Kym F, Toyokuni, Tatsushi

“…An accurate, rapid, and versatile method for the analysis of enzyme kinetics using electrospray ionization mass spectrometry (ESI-MS) has been developed and…”
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novel mass spectrometric assay for the cerebroside sulfate activator protein (saposin B) and arylsulfatase A by Norris, Andrew J, Whitelegge, Julian P, Yaghoubian, Arman, Alattia, Jean-Rene, Prive, Gilbert G, Toyokuni, Tatsushi, Sun, Hubert, Brooks, Mai N, Panza, Luigi, Matto, Pamela, Compostella, Federica, Remmel, Natascha, Klingenstein, Ralf, Sandhoff, Konrad, Fluharty, Claire, Fluharty, Arvan, Faull, Kym F

“…A mass spectrometric method is described for monitoring cerebrosides in the presence of excess concentrations of alkali metal salts. This method has been…”
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High throughput screening of small molecule libraries for modifiers of radiation responses by Kim, Kwanghee, Damoiseaux, Robert, Norris, Andrew J., Rivina, Leena, Bradley, Kenneth, Jung, Michael E., Gatti, Richard A., Schiestl, Robert H., Mcbride, William H.

“…Purpose: An unbiased approach of drug discovery through high-throughput screening (HTS) of libraries of chemically defined and bioactive small molecule…”
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Boric acid inhibits adenosine diphosphate-ribosyl cyclase non-competitively by Kim, Danny H., Hee, Shane Que, Norris, Andrew J., Faull, Kym F., Eckhert, Curtis D.

“…Adenosine diphosphate-ribosyl cyclase (ADP-ribosyl cyclase) is a ubiquitous enzyme in eukaryotes that converts NAD + to cyclic-ADP-ribose (cADPR) and…”
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EG-1 interacts with c-Src and activates its signaling pathway by MING LU, LIPING ZHANG, SARTIPPOUR, Maryam R, NORRIS, Andrew J, BROOKS, Mai N

“…EG-1 is significantly elevated in breast, colorectal, and prostate cancers. Overexpression of EG-1 stimulates cellular proliferation, and targeted inhibition…”
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Inhibition kinetics of carba- and C-fucosyl analogues of GDP-fucose against fucosyltransferase V: implication for the reaction mechanism by Norris, Andrew J., Whitelegge, Julian P., Strouse, M.Jane, Faull, Kym F., Toyokuni, Tatsushi

“…Inhibition kinetics of two isosteric analogues of GDP-fucose (GDP-Fuc) were investigated against fucosyltransferase V using electrospray ionization mass…”
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Kinetic Characterization of Enzyme Inhibitors Using Electrospray-Ionization Mass Spectrometry Coupled with Multiple Reaction Monitoring by Norris, Andrew J, Whitelegge, Julian P, Faull, Kym F, Toyokuni, Tatsushi

“…Electrospray ionization mass spectrometry coupled to multiple reaction monitoring (ESI-MS/MRM) has been applied for the first time to analyze enzyme inhibitor…”
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4 by Norris, Andrew J, McBride, William H, Kim, Kwanghee, Jung, Michael E, Cheng, Genhong, Sayre, James W, Iwamoto, Keisuke S, Ruchala, Piotr, Deng, Gang, Loo, Joseph, Micewicz, Ewa D, Nguyen, Christine, Schaue, Dörthe, Whitelegge, Julian P, Boxx, Gayle M, Damoiseaux, Robert D, Ratikan, Josephine A, Purbey, Prabhat

“…Our ability to use ionizing radiation as an energy source, as a therapeutic agent, and, unfortunately, as a weapon, has evolved tremendously over the past 120…”
Get full text

4 by Micewicz, Ewa D, Kim, Kwanghee, Iwamoto, Keisuke S, Ratikan, Josephine A, Cheng, Genhong, Boxx, Gayle M, Damoiseaux, Robert D, Whitelegge, Julian P, Ruchala, Piotr, Nguyen, Christine, Purbey, Prabhat, Loo, Joseph, Deng, Gang, Jung, Michael E, Sayre, James W, Norris, Andrew J, Schaue, Dörthe, McBride, William H

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4 by Micewicz, Ewa D, Kim, Kwanghee, Iwamoto, Keisuke S, Ratikan, Josephine A, Cheng, Genhong, Boxx, Gayle M, Damoiseaux, Robert D, Whitelegge, Julian P, Ruchala, Piotr, Nguyen, Christine, Purbey, Prabhat, Loo, Joseph, Deng, Gang, Jung, Michael E, Sayre, James W, Norris, Andrew J, Schaue, Dörthe, McBride, William H

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An active current sheet in the solar wind by Schwartz, Steven J, Chaloner, Chris P, Christiansen, Peter J, Coates, Andrew J, Hall, David S, Johnstone, Alan D, Gough, M. Paul, Norris, Andrew J, Rijnbeek, Richard P, Southwood, David J, Woolliscroft, Les J. C

“…The supersonic solar wind exhibits a variety of simple, small-scale (<10-min-observation duration) phenomena, including discontinuities and magnetic holes…”
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Arendt, Kant, and the Politics of Common Sense by Norris, Andrew

“…Hannah Arendt is best known for her argument that political action is a form of revelatory praxis. Such action would not be possible without the non-objective…”
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