Search Results - "Noronha Souza, Pedro Filho"
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Synthetic antimicrobial peptides: activity against vancomycin-resistant Enterococcus faecalis and modulation of chloramphenicol antibacterial activity
Published in Journal of applied microbiology (03-06-2024)“…Enterococcus faecalis (E. faecalis) is a leading cause of nosocomial infection and presents a wide spectrum of antibiotic resistance, being…”
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Recalculating the Route: Repositioning Antimicrobial Peptides for Cancer Treatment
Published in Chemistry & biodiversity (01-02-2024)“…Resistance to antimicrobial drugs has been considered a public health problem. Likewise, the increasing resistance of cancer cells to drugs currently used in…”
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Killing two birds with one stone: How do Plant Viruses Break Down Plant Defenses and Manipulate Cellular Processes to Replicate Themselves?
Published in Journal of plant biology = Singmul Hakhoe chi (01-06-2019)“…As simple organisms with a parasite nature, viruses have become masters in manipulating and subvert cellular components, including host proteins and…”
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Kinase Inhibitor Screening Displayed ALK as a Possible Therapeutic Biomarker for Gastric Cancer
Published in Pharmaceutics (01-09-2022)“…Despite advances in cancer chemotherapy, gastric cancer (GC) continues to have high recurrence rates and poor prognosis with limited treatment options…”
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The Polypeptides/Proteins Exuded from Mimosa caesalpiniifolia Seeds Induce Ultrastructural and Biomechanical Modifications of the Caenorhabditis elegans Surface and Inhibit the Nematode Motility
Published in Brazilian Archives of Biology and Technology (01-01-2024)“…Abstract Natural products have been studied as potential anthelmintic drugs. This study aimed to evaluate the effects of the polypeptides/proteins exuded from…”
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Antifungal activity of Caryocar brasiliense camb. Alone or along with antifungal agents against multidrug-resistant Candida auris
Published in Journal of ethnopharmacology (10-08-2024)“…Candida auris poses a severe global health threat, with many strains resistant to antifungal treatments, complicating therapy. Exploring natural compounds…”
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SARS-CoV‑2 Unrevealed: Ultrastructural and Nanomechanical Analysis
Published in Langmuir (14-09-2021)“…The ongoing outbreak of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) started in late 2019 and spread across the world, infecting millions…”
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Molecular characterization and biomarker discovery in gastric cancer progression through transcriptome meta-analysis
Published in Computers in biology and medicine (01-12-2024)“…Gastric cancer (GC) is a leading cause of cancer-related deaths globally. It is a multifactorial, molecularly heterogeneous disease whose carcinogenic patterns…”
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Chitosan and Chitooligosaccharides: Antifungal Potential and Structural Insights
Published in Chemistry & biodiversity (01-06-2024)“…Chitosan is a cationic polysaccharide derived from chitin deacetylation. This polysaccharide and its oligosaccharides have many biological activities and can…”
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High doses of graphene quantum dots impacts on microcirculation system: An observational study
Published in European journal of pharmaceutics and biopharmaceutics (01-07-2022)“…[Display omitted] Graphene and its derivatives are in the edge of technology with a wide and diverse range of applications. In the last years, especially…”
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A Review on Anaplastic Lymphoma Kinase (ALK) Rearrangements and Mutations: Implications for Gastric Carcinogenesis and Target Therapy
Published in Current protein & peptide science (01-01-2024)“…Gastric adenocarcinoma is a complex disease with diverse genetic modifications, including Anaplastic Lymphoma Kinase (ALK) gene changes. The ALK gene is…”
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Influence of carbonyl cyanide m-chlorophenyl hydrazone on biofilm dynamics, protease, and siderophore production by Burkholderia pseudomallei
Published in Biofouling (Chur, Switzerland) (13-09-2024)“…Efflux pump inhibitors are a potential therapeutic strategy for managing antimicrobial resistance and biofilm formation. This article evaluated the effect of…”
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Mo-CBP4, a purified chitin-binding protein from Moringa oleifera seeds, is a potent antidermatophytic protein: In vitro mechanisms of action, in vivo effect against infection, and clinical application as a hydrogel for skin infection
Published in International journal of biological macromolecules (15-04-2020)“…Dermatophytes belonging to Trichophyton ssp. are important anthropophilic and zoophilic pathogens, which developed resistance to griseofulvin, the common…”
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Nano-Nutraceuticals for Health: Principles and Applications
Published in Revista brasileira de farmacognosia (2023)“…The use of nanotechnological products is increasing steadily. In this scenario, the application of nanotechnology in food science and as a technological…”
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Zika Virus (ZIKV): A New Perspective on the Nanomechanical and Structural Properties
Published in Viruses (01-08-2022)“…Zika virus (ZIKV) is an arthropod-borne virus (arbovirus) from Flavivirus. In 2015, Brazil and other Latin American countries experienced an outbreak of ZIKV…”
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A resistant cowpea (Vigna unguiculata [L.] Walp.) genotype became susceptible to cowpea severe mosaic virus (CPSMV) after exposure to salt stress
Published in Journal of proteomics (01-03-2019)“…In nature, plants are simultaneously challenged by biotic and abiotic stresses. However, little is known about the effects of these combined stresses for most…”
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In vitro assessment of the efficacy of protein exudates from seeds against Haemonchus contortus
Published in Veterinary parasitology (01-04-2021)“…•Seed exudates could be an excellent source of bioactive protein.•Proteins from seed exudates inhibit the artificial exsheathment of H…”
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H2O2Accumulation, Host Cell Death and Differential Levels of Proteins Related to Photosynthesis, Redox Homeostasis, and Required for Viral Replication Explain the Resistance of EMS-mutagenized Cowpea to Cowpea Severe Mosaic Virus
Published in Journal of plant physiology (01-02-2020)“…Infection with Cowpea severe mosaic virus (CPSMV) represents one of the main limitations for cowpea (Vigna unguiculata L. Walp.) productivity due to the…”
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Physical virology: how physics is enabling a better understanding of recent viral invaders
Published in Biophysical reviews (01-08-2023)“…The world is frequently afflicted by several viral outbreaks that bring diseases and health crises. It is vital to comprehend how viral assemblies’ fundamental…”
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Nanomechanical and Vibrational Signature of Chikungunya Viral Particles
Published in Viruses (01-12-2022)“…Chikungunya virus (CHIKV) belongs to the genus Alphaviridae, with a single-stranded positive-sense RNA genome of 11.8 kbp encoding a polyprotein that generates…”
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