Search Results - "Noronha, Lucia"
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Zika virus damages the human placental barrier and presents marked fetal neurotropism
Published in Memórias do Instituto Oswaldo Cruz (01-05-2016)“…An unusually high incidence of microcephaly in newborns has recently been observed in Brazil. There is a temporal association between the increase in cases of…”
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2
IL-4/IL-13 remodeling pathway of COVID-19 lung injury
Published in Scientific reports (29-10-2020)“…The COVID-19 fatality rate is high when compared to the H1N1pdm09 (pandemic Influenza A virus H1N1 subtype) rate, and although both cause an aggravated…”
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3
Combined Biomaterials: Amniotic Membrane and Adipose Tissue to Restore Injured Bone as Promoter of Calcification in Bone Regeneration: Preclinical Model
Published in Calcified tissue international (01-05-2021)“…Discarded tissues, like human amniotic membranes and adipose tissue, were investigated for the application of Decellularized Human Amniotic Membrane (DAM) as a…”
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COVID-19: Immunohistochemical Analysis of TGF-β Signaling Pathways in Pulmonary Fibrosis
Published in International journal of molecular sciences (24-12-2021)“…Acute respiratory distress syndrome (ARDS) followed by repair with lung remodeling is observed in COVID-19. These findings can lead to pulmonary terminal…”
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Zika Virus Infection at Different Pregnancy Stages: Anatomopathological Findings, Target Cells and Viral Persistence in Placental Tissues
Published in Frontiers in microbiology (25-09-2018)“…Zika virus (ZIKV) infection in humans has been associated with congenital malformations and other neurological disorders, such as Guillain-Barré syndrome. The…”
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6
Zika virus and pregnancy: An overview
Published in American journal of reproductive immunology (1989) (01-02-2017)“…In May 2015, the first episodes of Zika virus infection of the Latin America were confirmed in Brazil, where currently 196 976 cases were reported. The main…”
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Cellular Therapy in Experimental Autoimmune Encephalomyelitis as an Adjuvant Treatment to Translate for Multiple Sclerosis
Published in International journal of molecular sciences (26-06-2024)“…This study aims to evaluate and compare cellular therapy with human Wharton's jelly (WJ) mesenchymal stem cells (MSCs) and neural precursors (NPs) in…”
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8
Structural assessments in decellularized extracellular matrix of porcine semilunar heart valves: Evaluation of cell niches
Published in Xenotransplantation (Københaven) (01-05-2019)“…Tissue‐engineered heart valves aim to reproduce the biological properties of natural valves with anatomically correct structure and physiological performance…”
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Transcriptomic profiling of cardiac tissues from SARS‐CoV‐2 patients identifies DNA damage
Published in Immunology (01-03-2023)“…The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is known to present with pulmonary and extra‐pulmonary organ complications. In comparison with…”
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Alcohol and tobacco consumption affects bacterial richness in oral cavity mucosa biofilms
Published in BMC microbiology (03-10-2014)“…Today there are more than 2 billion alcohol users and about 1.3 billion tobacco users worldwide. The chronic and heavy use of these two substances is at the…”
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Endothelial cells are not productively infected by SARS‐CoV‐2
Published in Clinical & translational immunology (2021)“…Objectives Thrombotic and microvascular complications are frequently seen in deceased COVID‐19 patients. However, whether this is caused by direct viral…”
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DNA methylation-based depiction of the immune microenvironment and immune-associated long non-coding RNAs in oral cavity squamous cell carcinomas
Published in Biomedicine & pharmacotherapy (01-11-2023)“…Oral cavity squamous cell carcinoma (OSCC) is a complex and dynamic disease characterized by clinicopathological and molecular heterogeneity. Spatial and…”
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Biomolecular engineering of antidehydroepiandrosterone antibodies: a new perspective in cancer diagnosis and treatment using single-chain antibody variable fragment
Published in Nanomedicine (London, England) (01-03-2019)“…To develop a monoclonal antibody against dehydroepiandrosterone (DHEA) and miniaturize it, generating a single-chain antibody variable fragment (scFv) against…”
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14
COVID-19 and Lung Mast Cells: The Kallikrein-Kinin Activation Pathway
Published in International journal of molecular sciences (02-02-2022)“…Mast cells (MCs) have relevant participation in inflammatory and vascular hyperpermeability events, responsible for the action of the kallikrein-kinin system…”
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15
Expression of Parkin, APC, APE1, and Bcl-xL in Colorectal Polyps
Published in The journal of histochemistry and cytochemistry (01-07-2021)“…Colorectal cancer can develop through molecular, chromosomal, and epigenetic cumulative changes that transform the normal intestinal epithelium into the…”
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Impact of smoking on dendritic cells in patients with oral squamous cell carcinoma
Published in Brazilian oral research (01-01-2021)“…Abstract Smoking has been shown to alter innate and adaptive immune responses and is directly associated with the onset of oral squamous cell carcinoma (OSCC)…”
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Decellularized Wharton's Jelly and Amniotic Membrane Demonstrate Potential Therapeutic Implants in Tracheal Defects in Rabbits
Published in Life (Basel, Switzerland) (01-06-2024)“…Tracheal grafts have been investigated for over a century, aiming to replace various lesions. However, tracheal reconstruction surgery remains a challenge,…”
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Mast Cells in Alveolar Septa of COVID-19 Patients: A Pathogenic Pathway That May Link Interstitial Edema to Immunothrombosis
Published in Frontiers in immunology (18-09-2020)“…It is currently believed that innate immunity is unable to prevent the spread of SARS-CoV-2 from the upper airways to the alveoli of high-risk groups of…”
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Geographical evaluation of Neuroparacoccidioidomycosis and Paracoccidioidomycosis in Southern Brazil
Published in Mycoses (01-08-2018)“…Summary Paracoccidioidomycosis (PCM) is the most prevalent systemic mycosis among immunocompetent patients in Latin America. This study aimed to describe the…”
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Potential of Human Neural Precursor Cells in Diabetic Retinopathy Therapeutics - Preclinical Model
Published in Current eye research (04-03-2022)“…This study aimed to evaluate a cell therapy strategy with human neural precursor cells (hNPCs) to treat diabetic retinopathy (DR) in Wistar rats induced to…”
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