Search Results - "Norman, J C"

1550-nm Driven ErAs:In(Al)GaAs Photoconductor-Based Terahertz Time Domain System with 6.5 THz Bandwidth by Nandi, U., Norman, J. C., Gossard, A. C., Lu, H., Preu, S.

“…ErAs:In(Al)GaAs superlattice photoconductors are grown using molecular beam epitaxy (MBE) with excellent material characteristics for terahertz time-domain…”
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Mutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion by Muller, P A J, Trinidad, A G, Timpson, P, Morton, J P, Zanivan, S, van den Berghe, P V E, Nixon, C, Karim, S A, Caswell, P T, Noll, J E, Coffill, C R, Lane, D P, Sansom, O J, Neilsen, P M, Norman, J C, Vousden, K H

“…Tumour-derived mutant p53 proteins promote invasion, in part, by enhancing Rab coupling protein (RCP)-dependent receptor recycling. Here we identified MET as…”
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Mechanical stretch has contrasting effects on mediator release from bronchial epithelial cells, with a rho-kinase-dependent component to the mechanotransduction pathway by Thomas, R.A., Norman, J.C., Huynh, T.T., Williams, B., Bolton, S.J., Wardlaw, A.J.

“…In vivo , the airway epithelium stretches and relaxes with each respiratory cycle, but little is known about the effect this pattern of elongation and…”
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ARF6 directs axon transport and traffic of integrins and regulates axon growth in adult DRG neurons by Eva, Richard, Crisp, Sarah, Marland, Jamie R K, Norman, Jim C, Kanamarlapudi, Venkateswarlu, ffrench-Constant, Charles, Fawcett, James W

“…Integrins are involved in axon growth and regeneration. Manipulation of integrins is a route to promoting axon regeneration and understanding regeneration…”
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ARF1 Mediates Paxillin Recruitment to Focal Adhesions and Potentiates Rho-Stimulated Stress Fiber Formation in Intact and Permeabilized Swiss 3T3 Fibroblasts by Norman, J. C., Jones, D., Barry, S. T., Holt, M. R., Cockcroft, S., Critchley, D. R.

“…Focal adhesion assembly and actin stress fiber formation were studied in serum-starved Swiss 3T3 fibroblasts permeabilized with streptolysin-O…”
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Primaquine, an inhibitor of vesicular transport, blocks the calcium-release-activated current in rat megakaryocytes by Somasundaram, B, Norman, J C, Mahaut-Smith, M P

“…The whole-cell patch-clamp technique was used to study the effect of primaquine, an inhibitor of vesicular transport, on the calcium-release-activated current…”
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Actin Filament Organization in Activated Mast Cells Is Regulated by Heterotrimeric and Small GTP-Binding Proteins by Norman, James C., Price, Leo S., Ridley, Anne J., Hall, Alan, Koffer, Anna

“…Rat peritoneal mast cells, both intact and permeabilized, have been used widely as model secretory cells. GTP-binding proteins and calcium play a major role in…”
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Epigenetic inactivation of protein kinase D1 in gastric cancer and its role in gastric cancer cell migration and invasion by Kim, Mirang, Jang, Hay-Ran, Kim, Jeong-Hwan, Noh, Seung-Moo, Song, Kyu-Sang, Cho, June-Sik, Jeong, Hyun-Yong, Norman, Jim C., Caswell, Patrick T., Kang, Gyeong Hoon, Kim, Seon-Young, Yoo, Hyang-Sook, Kim, Yong Sung

“…Protein kinase D (PKD) 1 influences cell migration by mediating both trans-Golgi vesicle fission and integrin recycling to the cell surface. Using restriction…”
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RhoB and Actin Polymerization Coordinate Src Activation with Endosome-Mediated Delivery to the Membrane by Sandilands, Emma, Cans, Christophe, Fincham, Valerie J., Brunton, Valerie G., Mellor, Harry, Prendergast, George C., Norman, Jim C., Superti-Furga, Giulio, Frame, Margaret C.

“…We have used a c-Src-GFP fusion protein to address the spatial control of Src activation and the nature of Src-associated intracellular structures during…”
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Binding of monomeric immunoglobulin G triggers Fc gamma RI-mediated endocytosis by Harrison, P T, Davis, W, Norman, J C, Hockaday, A R, Allen, J M

“…Cross-linking of leukocyte Fc receptors specific for IgG (Fc gamma Rs) by multivalent IgG complexes triggers a wide range of immune functions. Many of these…”
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Dynamic studies of zirconia crystallization by MAMOTT, G. T, BARNES, P, TARLING, S. E, JONES, S. L, NORMAN, C. J

“…Zr hydroxide is a precursor material of ZrO sub 2 ; variations in its chemical and physical properties affect the properties of the final product. The effects…”
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Protein kinase B/Akt acts via glycogen synthase kinase 3 to regulate recycling of alpha v beta 3 and alpha 5 beta 1 integrins by Roberts, Marnie S, Woods, Alison J, Dale, Trevor C, Van Der Sluijs, Peter, Norman, Jim C

“…Protein kinase B (PKB)/Akt is known to promote cell migration, and this may contribute to the enhanced invasiveness of malignant cells. To elucidate potential…”
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Paxillin Associates with Poly(A)-binding Protein 1 at the Dense Endoplasmic Reticulum and the Leading Edge of Migrating Cells by Woods, Alison J., Roberts, Marnie S., Choudhary, Jyoti, Barry, Simon T., Mazaki, Yuichi, Sabe, Hisataka, Morley, Simon J., Critchley, David R., Norman, Jim C.

“…Using mass spectrometry we have identified proteins which co-immunoprecipitate with paxillin, an adaptor protein implicated in the integrin-mediated signaling…”
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Lysosomal routing of FcγRI from early endosomes requires recruitment of tyrosine kinases by Norman, J C, Harrison, P T, Davis, W, Floto, R A, Allen, J M

“…The high‐affinity receptor for imm_unoglobulin G (FcγRI) plays a central role in the clearance of imm_une complexes by mediating their internalization and…”
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A ventricular assist device powered by conditioned skeletal muscle by Whalen, Robert L, Richards, Christopher L, Lim, Gilbert W, Sherman, Craig W, Norman, John C, Bearnson, Gill B, Burns, Gregory L, Olsen, Donald B

“…Background. We are developing and testing a new ventricular assist device (VAD) to be powered by conditioned skeletal muscle. Methods. To evaluate the VAD…”
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Synchrotron-related studies on the dynamic and structural aspects of zirconia synthesis for ceramic and catalytic applications by Turrillas, X., Barnes, P., Gascoigne, D., Turner, J.Z., Jones, S.L., Norman, C.J., Pygall, C.F., Dent, A.J.

“…Zirconia is an important component material for several industrial applications. In these studies we have used intense radiation sources, primarily synchrotron…”
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Quantum dot lasers based photonics integrated circuits by Grillot, F., Duan, J., Dong, B., Huang, H., Liu, S., Chow, W. W., Norman, J. C., Bowers, J. E.

“…Photonic integrated circuits enable energy efficient and compact technologies for modern information communications. Here, we explore semiconductor epitaxial…”
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Performance of a 1030 nm driven ErAs: InGaAs photoconductive receiver at high THz average power by Nandi, U., Vogel, T., Mansourzadeh, S., Hoffmann, M., Norman, J. C., Lu, H., Gossard, A. C., Saraceno, C. J., Preu, S.

“…We demonstrate a 1030 nm 520 fs-pulse-driven ErAs: InGaAs photoconductive receiver suitable for detecting 14 mW average THz power (~ 950 nJ pulse energy). To…”
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Frequency-domain modeling of semiconductor mode lock lasers by Chow, W. W., Liu, S., Norman, J. C., Duan, J., Grillot, F., Bowers, J. E.

“…A frequency-domain description of semiconductor mode-locked lasers is presented. The approach provides self-consistent accounting of locking mechanism, gain…”
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The small GTP-binding proteins, Rac and Rho, regulate cytoskeletal organization and exocytosis in mast cells by parallel pathways by Norman, J C, Price, L S, Ridley, A J, Koffer, A

“…In mast cells, activation of GTP-binding proteins induces centripetal reorganization of actin filaments. This effect is due to disassembly, relocalization, and…”
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