Search Results - "Norman, F."
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Design of cell–matrix interactions in hyaluronic acid hydrogel scaffolds
Published in Acta biomaterialia (01-04-2014)“…The design of hyaluronic acid (HA)-based hydrogel scaffolds to elicit highly controlled and tunable cell response and behavior is a major field of interest in…”
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2
Suppression of Circadian Timing and Its Impact on the Hippocampus
Published in Frontiers in neuroscience (08-04-2021)“…In this article, I describe the development of the disruptive phase shift (DPS) protocol and its utility for studying how circadian dysfunction impacts memory…”
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Domestication of Pea ( Pisum sativum L.): The Case of the Abyssinian Pea
Published in Frontiers in plant science (18-04-2018)“…Phylogenetic relationships of the Abyssinian pea ( ssp. ) to other subspecies and species in the genus were investigated to test between different hypotheses…”
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Mammographic density and breast cancer risk: current understanding and future prospects
Published in Breast cancer research : BCR (01-11-2011)“…Variations in percent mammographic density (PMD) reflect variations in the amounts of collagen and number of epithelial and non-epithelial cells in the breast…”
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Emergence of potentially disinfection-resistant, naturalized Escherichia coli populations across food- and water-associated engineered environments
Published in Scientific reports (12-06-2024)“…The Escherichia coli species is comprised of several ‘ecotypes’ inhabiting a wide range of host and natural environmental niches. Recent studies have suggested…”
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First-in-human testing of a wirelessly controlled drug delivery microchip
Published in Science translational medicine (22-02-2012)“…The first clinical trial of an implantable microchip-based drug delivery device is discussed. Human parathyroid hormone fragment (1-34) [hPTH(1-34)] was…”
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It’s All in the Delivery: Designing Hydrogels for Cell and Non-viral Gene Therapies
Published in Molecular therapy (05-09-2018)“…Hydrogels provide a regenerative medicine platform with their ability to create an environment that supports transplanted or endogenous infiltrating cells and…”
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Prevalence, levels and seasonal variations of human enteric viruses in six major rivers in Alberta, Canada
Published in Water research (Oxford) (15-04-2019)“…The prevalence and seasonal variation of 7 viruses in 6 major rivers in Alberta were assessed using a combination of qPCR, cell culture and integrated cell…”
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Microporous annealed particle hydrogel stiffness, void space size, and adhesion properties impact cell proliferation, cell spreading, and gene transfer
Published in Acta biomaterialia (01-08-2019)“…[Display omitted] Designing scaffolds for polyplex-mediated therapeutic gene delivery has a number of applications in regenerative medicine, such as for tissue…”
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Extracellular histones are essential effectors of C5aR‐ and C5L2‐mediated tissue damage and inflammation in acute lung injury
Published in The FASEB journal (01-12-2013)“…We investigated how complement activation promotes tissue injury and organ dysfunction during acute inflammation. Three models of acute lung injury (ALI)…”
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A 13-Steroid Serum Panel Based on LC-MS/MS: Use in Detection of Adrenocortical Carcinoma
Published in Clinical chemistry (Baltimore, Md.) (01-12-2017)“…Adrenocortical carcinoma (ACC) is a rare malignancy, with an annual incidence of 1 or 2 cases per million. Biochemical diagnosis is challenging because up to…”
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12
Mammographic Density and the Risk and Detection of Breast Cancer
Published in The New England journal of medicine (18-01-2007)“…The light appearance of epithelium and stroma in a mammogram (mammographic density) can hide the presence of a cancer. A careful study of this problem found…”
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Use of dissected paraffin block tissue as a source of mRNA for transcriptional profiling and biomarker identification: a review, with preliminary findings in adrenocortical carcinoma tissue
Published in Acta biochimica polonica (27-05-2022)“…Cancer tissue obtained by biopsy or at surgery is usually handled and stored as formalin-fixed, paraffin-embedded (FFPE) blocks. While primarily prepared for…”
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Intrasinusoidal bone marrow involvement in mantle cell lymphoma: a case series with review of the main differential diagnoses
Published in Virchows Archiv : an international journal of pathology (06-08-2024)“…Intrasinusoidal bone marrow involvement is an infrequent histological pattern observed in a limited number of B and T cell lymphomas. Mantle cell lymphoma is a…”
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15
Dysrhythmia in the suprachiasmatic nucleus inhibits memory processing
Published in Science (American Association for the Advancement of Science) (14-11-2014)“…Chronic circadian dysfunction impairs declarative memory in humans but has little effect in common rodent models of arrhythmia caused by clock gene knockouts…”
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Demonstration of 4H-SiC Digital Integrated Circuits Above 800 °C
Published in IEEE electron device letters (01-08-2017)“…Short-term demonstrations of packaged 4H-SiC junction field-effect transistor (JFET) logic integrated circuits (ICs) at temperatures exceeding 800 °C in air…”
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Melanopsin as a sleep modulator: circadian gating of the direct effects of light on sleep and altered sleep homeostasis in Opn4(-/-) mice
Published in PLoS biology (09-06-2009)“…Light influences sleep and alertness either indirectly through a well-characterized circadian pathway or directly through yet poorly understood mechanisms…”
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Encapsulation of PEGylated low-molecular-weight PEI polyplexes in hyaluronic acid hydrogels reduces aggregation
Published in Acta biomaterialia (01-12-2015)“…[Display omitted] The effective delivery of DNA locally could increase the applicability of gene therapy in tissue regeneration and therapeutic angiogenesis…”
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Evidence for the evolution, clonal expansion and global dissemination of water treatment-resistant naturalized strains of Escherichia coli in wastewater
Published in Water research (Oxford) (01-06-2019)“…We previously demonstrated the existence of naturalized strains of E. coli in wastewater and herein perform an in-depth comparative whole genome analysis of…”
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Evidence that breast tissue stiffness is associated with risk of breast cancer
Published in PloS one (10-07-2014)“…Evidence from animal models shows that tissue stiffness increases the invasion and progression of cancers, including mammary cancer. We here use measurements…”
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