Search Results - "Nork, T. M."

Subtherapeutic Ocular Penetration of Caspofungin and Associated Treatment Failure in Candida albicans Endophthalmitis by Gauthier, G. M., Nork, T. M., Prince, R., Andes, D.

“…Candida endophthalmitis represents the most serious ocular complication of candidemia. The pharmacokinetics and pharmacodynamics of fluconazole, amphotericin…”
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Nuclear exclusion of Wild-type p53 in immortalized human retinoblastoma cells by SCHLAMP, C. L, POULSEN, G. L, NORK, T. M, NICKELLS, R. W

“…Retinoblastoma is the most common childhood tumor of the eye, arising from cells that are defective in both copies of the retinoblastoma susceptibility gene…”
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Regional choroidal blood flow and multifocal electroretinography in experimental glaucoma in rhesus macaques by Nork, T Michael, Kim, Charlene B Y, Munsey, Kaitlyn M, Dashek, Ryan J, Hoeve, James N Ver

“…To test a hypothesis of regional variation in the effect of experimental glaucoma on choroidal blood flow (ChBF) and retinal function. Five rhesus macaques…”
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Vision loss following snakebite in a patient with controlled aplastic anemia by Kweon, EY(Chonbuk National University Medical School Department of Ophthalmology), Lee, DW(Chonbuk National University Medical School Department of Ophthalmology), Ahn, M(Chonbuk National University Medical School Department of Ophthalmology), Nork, TM(University of Wisconsin Medical School Department of Ophthalmology and Visual Sciences), Cho, NC(Chonbuk National University Medical School Department of Ophthalmology)

“…Viper venoms act mainly on blood and blood vessels. Reports of ophthalmic manifestations after snakebite include ptosis and ophthalmoplegia. In the current…”
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Treatment and histopathology of a congenital vitreous cyst by Nork, T M, Millecchia, L L

“…This study aimed to evaluate the treatment efficacy of a congenital vitreous cyst and to examine the cyst histopathologically to determine its cellular makeup…”
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Implications of retinal effects observed in chronic toxicity studies on the clinical development of a CNS-active drug candidate by Eichenbaum, G., Zhou, J., Kelley, M.F., Roosen, W., Costa-Giomi, P., Louden, C., Di Prospero, N.A., Pandina, G., Singh, J.B., Ford, L., Moyer, J.A., Nork, T.M., Ver Hoeve, J.N., Aguirre, G.D.

“…•Retinal effects were observed in nonclinical studies with a drug candidate.•Light induced retinal degeneration occurred in non-pigmented but not pigmented…”
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Rods and cones contain antigenically distinctive S-antigens by Nork, TM, Mangini, NJ, Millecchia, LL

“…S-antigen (48 kDa protein or arrestin) is known to be present in rod photoreceptors. Its localization in cones is less clear with several conflicting reports…”
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Acquired color vision loss and a possible mechanism of ganglion cell death in glaucoma by Nork, T M

“…First, to study the cellular mechanisms of acquired color vision loss in retinal detachment and diabetic retinopathy. Second, to learn why, in glaucoma, the…”
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Distribution of carbonic anhydrase among human photoreceptors by Nork, TM, McCormick, SA, Chao, GM, Odom, JV

“…The distribution of carbonic anhydrase (CA) among human photoreceptors has been a topic of dispute. In our experiments, by modifying an established enzyme…”
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Swelling and loss of photoreceptors in chronic human and experimental glaucomas by Nork, T M, Ver Hoeve, J N, Poulsen, G L, Nickells, R W, Davis, M D, Weber, A J, Vaegan, Sarks, S H, Lemley, H L, Millecchia, L L

“…To determine whether outer retinal changes occur in chronic, presumed primary open-angle glaucoma (POAG). The outer retinas from 128 human eyes with a…”
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Immunolocalization of the retinoblastoma protein in the human eye and in retinoblastoma by Nork, TM, Millecchia, LL, Poulsen, G

“…To determine whether, by employing recent advances in immunocytochemical technique, it is possible to identify reliably the product of the retinoblastoma (RB)…”
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Immunostaining of preretinal membranes for actin, fibronectin, and glial fibrillary acidic protein by Sramek, S J, Wallow, I H, Stevens, T S, Nork, T M

“…The frequency and extent of immunostaining for actin, fibronectin (FN), and glial fibrillary acidic protein (GFAP) were determined in 37 preretinal membranes…”
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Effect of H-7 and Lat-B on Retinal Physiology by Kiland, J. A., Miller, C. L., Kim, C. B. Y., Ver Hoeve, J. N., Gabelt, B. T., Peterson, J., Nork, T. M., Kaufman, P. L.

“…Purpose: To investigate the effects of H-7 and Latrunculin B (Lat-B) on retinal vascular permeability and electrophysiology at concentrations that increase…”
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Acetazolamide affects performance on the Nagel II anomaloscope by LEYS, M. J. J, VAN SLYCKEN, S, NORK, T. M, ODOM, J. V

“…Recent reports have indicated that acetazolamide alters human electroretinograms. We wished to determine the effects of administering acetazolamide on…”
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The effects of acetazolamide in albino rabbits, pigmented rabbits, and humans by Odom, J V, Nork, T M, Schroeder, B M, Cavender, S A, van Slycken, S, Leys, M

“…In three separate experiments albino rabbits, pigmented rabbits, and humans were tested following administration of acetazolamide and without acetazolamide. In…”
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Molecular etiology of low-penetrance retinoblastoma in two pedigrees by DRYJA, T. P, RAPAPORT, J, MCGEE, T. L, NORK, T. M, SCHWARTZ, T. L

“…In one family with low-penetrance retinoblastoma, a germ-line deletion is shared by affected and unaffected, obligate carriers. The deletion encompasses exon 4…”
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p53 regulates apoptosis in human retinoblastoma by Nork, T M, Poulsen, G L, Millecchia, L L, Jantz, R G, Nickells, R W

“…To determine whether apoptosis is a significant mode of cell death in human retinoblastoma (RB) and if it is regulated by the expression of p53. Apoptosis was…”
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Pigment distribution in Waardenburg's syndrome: a new hypothesis by NORK, T. M, SHIBAB, Z. M, YOUNG, R. S. L, PRICE, J

“…Two cases of Waardenburg's syndrome are presented. The first case is an example of Waardenburg's type II (without dystopia canthorum) with bilateral sectoral…”
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Protection of ganglion cells in experimental glaucoma by retinal laser photocoagulation by Nork, T M, Poulsen, G L, Nickells, R W, Ver Hoeve, J N, Cho, N C, Levin, L A, Lucarelli, M J

“…To test a hypothesis of photoreceptor involvement in retinal ganglion cell (RGC) death in chronic glaucoma. Laser spots were applied to 6 eyes of 3 rhesus…”
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Retinoblastoma in a dog by Syed, N A, Nork, T M, Poulsen, G L, Riis, R C, George, C, Albert, D M

“…To describe and classify a retinal tumor found in a dog that histologically resembles human retinoblastoma and to discuss the molecular mechanisms of retinal…”
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