Search Results - "Norjavaara, E."

Effect of exogenously administered glucagon versus spontaneous endogenous counter-regulation on glycaemic recovery from insulin-induced hypoglycaemia in patients with type 2 diabetes treated with a novel glucokinase activator, AZD1656, and metformin by Krentz, A. J., Morrow, L., Petersson, M., Norjavaara, E., Hompesch, M.

“…Aims To study the effect of exogenous i.m. glucagon on recovery from controlled insulin‐induced hypoglycaemia in patients with type 2 diabetes treated with the…”
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Safety, pharmacokinetics and pharmacodynamics of multiple-ascending doses of the novel glucokinase activator AZD1656 in patients with type 2 diabetes mellitus by Morrow, L. A., Leonsson-Zachrisson, M., Ericsson, H., Wollbratt, M., Knutsson, M., Hompesch, M., Norjavaara, E.

“…Aims To assess the safety, pharmacokinetics and pharmacodynamics of multiple‐ascending doses of the novel glucokinase activator AZD1656 in patients with type 2…”
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Higher than expected estradiol levels in aromatase inhibitor-treated, postmenopausal breast cancer patients by Kunovac Kallak, T., Baumgart, J., Stavreus Evers, A., Sundström Poromaa, I., Moby, L., Kask, K., Norjavaara, E., Kushnir, M. M., Bergquist, J., Nilsson, K.

“…ABSTRACT Objective Vaginal estradiol is considered contraindicated in aromatase inhibitor (AI)-treated patients because of the risk of elevated estrogen…”
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Pharmacodynamic effects of the oral glucokinase activator AZD6370 after single doses in healthy volunteers assessed with euglycaemic clamp by Sjöstrand, M., Ericsson, H., Hartford, M., Norjavaara, E., Eriksson, J. W.

“…Aims This study evaluated the safety, tolerability, pharmacokinetics and pharmacodynamic effects of the glucokinase activator (GKA) AZD6370 in non‐diabetic…”
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Parental influence on bone mineral density in Swedish children and adolescents with inflammatory bowel disease by Schmidt, S, Mellström, D, Norjavaara, E, Sundh, V, Saalman, R

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Serum leptin concentrations in relation to pubertal development by Carlsson, Björn, Ankarberg, Carina, Rosberg, Sten, Norjavaara, Ensio, Albertsson-Wikland, Kerstin, Carlsson, Lena M S

“…OBJECTIVES The amount of adipose tissue influences pubertal development and fertility in girls. A candidate for mediating this is the hormone leptin, derived…”
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Diurnal rhythm of 17β-estradiol secretion throughout pubertal development in healthy girls : Evaluation by a sensitive radioimmunoassay by NORJAVAARA, E, ANKARBERG, C, ALBERTSSON-WIKLAND, K

“…Puberty is initiated by a nocturnal rise in gonadotropin secretion, which, in boys, results in an increased nocturnal secretion of testosterone. To…”
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Leptin levels show diurnal variation throughout puberty in healthy children, and follow a gender-specific pattern by ANKARBERG-LINDGREN, Carina, DAHLGREN, Jovanna, CARLSSON, Björn, ROSBERG, Sten, CARLSSON, Lena, ALBERTSSON WIKLAND, Kerstin, NORJAVAARA, Ensio

“…To investigate the levels and diurnal rhythm of serum leptin in healthy children, and to investigate the association between leptin levels and sex steroids…”
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Inhibition of Estrogen Biosynthesis with a Potent Aromatase Inhibitor Increases Predicted Adult Height in Boys with Idiopathic Short Stature: A Randomized Controlled Trial by Hero, Matti, Norjavaara, Ensio, Dunkel, Leo

“…Context: In males as well as in females, estrogen is an essential regulator of bone maturation, growth plate fusion, and cessation of longitudinal growth…”
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Elevated levels of growth hormone increase bone mineral content in normal young mice, but not in ovariectomized mice by Sandstedt, J, Törnell, J, Norjavaara, E, Isaksson, O G, Ohlsson, C

“…Both estrogens and GH are necessary for normal bone remodeling. This study investigates the effect of elevated GH levels on the amount and density of bone in…”
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Management of puberty in constitutional delay of growth and puberty by De Luca, F, Argente, J, Cavallo, L, Crowne, E, Delemarre-Van de Waal, H A, De Sanctis, C, Di Maio, S, Norjavaara, E, Oostdijk, W, Severi, F, Tonini, G, Trifirò, G, Voorhoeve, P G, Wu, F

“…Constitutional delay of growth and puberty (CDGP) is the most common presenting form of short stature, but no single test can infallibly discriminate CDGP and…”
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Pediatric reference intervals for serum testosterone and estradiol by Ankarberg-Lindgren, C., Norjavaara, E.

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Synthesis of prostaglandin F2 alpha, E2 and prostacyclin in isolated corpora lutea of adult pseudopregnant rats throughout the luteal life-span by Olofsson, J, Norjavaara, E, Selstam, G

“…The ability of de novo biosynthesis of prostaglandins (PGs) in individual whole corpora lutea (CL) obtained from sterile-mated adult pseudopregnant rats on…”
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Optimal Pubertal Induction in Girls with Turner Syndrome Using Either Oral or Transdermal Estradiol: A Proposed Modern Strategy by Donaldson, Malcolm, Kriström, Berit, Ankarberg-Lindgren, Carina, Verlinde, Siska, van Alfen-van der Velden, Janiëlle, Gawlik, Aneta, van Gelder, Marleen M H J, Sas, Theo

“…Most girls with Turner syndrome (TS) require pubertal induction with estrogen, followed by long term replacement. However, no adequately powered prospective…”
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Normal pregnancy outcomes in a population-based study including 2968 pregnant women exposed to budesonide by Norjavaara, Ensio, de Verdier, Maria Gerhardsson

“…Background: Inhaled corticosteroids are recommended as first-line therapy for pregnant women with moderate to severe asthma, although the effects on pregnancy…”
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Changes of diurnal rhythm and levels of total and free testosterone secretion from pre to late puberty in boys: testis size of 3 ml is a transition stage to puberty by Ankarberg-Lindgren, C, Norjavaara, E

“…OBJECTIVE: To establish levels for comparison for 24-h total and free serum testosterone in prepubertal boys and throughout pubertal development. DESIGN: The…”
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Effects of hysterectomy and uterine decidualization on in vivo levels of prostaglandins in the corpus luteum of adult pseudopregnant rats by OLOFSSON, J, NORJAVAARA, E

“…A possible role of the uterus in regulating content of luteal prostaglandins (PGs) was investigated. Pseudopregnancy was induced in adult virgin female rats by…”
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Multiple pituitary hormone deficiency: management of puberty for optimal auxological results by Stanhope, R, De Luca, F, Delemarre-Van de Waal, H A, Liotta, A, Norjavaara, E, Salvatoni, A, Wu, F

“…The overview in this paper focuses on ways of achieving optimal auxological results in puberty, principally in idiopathic and congenital multiple pituitary…”
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A specific aromatase inhibitor and potential increase in adult height in boys with delayed puberty: a randomised controlled trial by Wickman, Sanna, Sipilä, Ilkka, Ankarberg-Lindgren, Carina, Norjavaara, Ensio, Dunkel, Leo

“…The role of oestrogens in the closure of growth plates in both sexes is unequivocal. We postulated that inhibition of oestrogen synthesis in boys with delayed…”
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Diurnal rhythm of testosterone secretion before and throughout puberty in healthy girls : Correlation with 17β-estradiol and dehydroepiandrosterone sulfate by ANKARBERG, C, NORJAVAARA, E

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