Search Results - "Noriko Sumi"

Tumor Necrosis Factor-α Mediates the Blood–Brain Barrier Dysfunction Induced by Activated Microglia in Mouse Brain Microvascular Endothelial Cells by Nishioku, Tsuyoshi, Matsumoto, Junichi, Dohgu, Shinya, Sumi, Noriko, Miyao, Kenji, Takata, Fuyuko, Shuto, Hideki, Yamauchi, Atsushi, Kataoka, Yasufumi

“…The present study was designed to elucidate the involvement of tumor necrosis factor-α (TNF-α) release from activated microglia in the induction of blood–brain…”
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Lipopolysaccharide-activated microglia lower P-glycoprotein function in brain microvascular endothelial cells by Matsumoto, Junichi, Dohgu, Shinya, Takata, Fuyuko, Nishioku, Tsuyoshi, Sumi, Noriko, Machida, Takashi, Takahashi, Hiroyuki, Yamauchi, Atsushi, Kataoka, Yasufumi

“…► In an RBEC monolayer, LPS showed no effect on P-gp function. ► In the presence of microglia, LPS lowered P-gp function in RBECs. ► LPS-activated microglia…”
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Cyclosporin A induces hyperpermeability of the blood–brain barrier by inhibiting autocrine adrenomedullin-mediated up-regulation of endothelial barrier function by Dohgu, Shinya, Sumi, Noriko, Nishioku, Tsuyoshi, Takata, Fuyuko, Watanabe, Takuya, Naito, Mikihiko, Shuto, Hideki, Yamauchi, Atsushi, Kataoka, Yasufumi

“…Cyclosporin A, a potent immunosuppressant, can often produce neurotoxicity in patients, although its penetration into the brain is restricted by the…”
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Oncostatin M induces functional and structural impairment of blood–brain barriers comprised of rat brain capillary endothelial cells by Takata, Fuyuko, Sumi, Noriko, Nishioku, Tsuyoshi, Harada, Eriko, Wakigawa, Tomoya, Shuto, Hideki, Yamauchi, Atsushi, Kataoka, Yasufumi

“…Oncostatin M (OSM), a member of the interleukin-6 family, is produced by monocytes and macrophages in the peripheral blood and microglia in the brain. The…”
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Cell Cycle-dependent Expression and Spindle Pole Localization of a Novel Human Protein Kinase, Aik, Related to Aurora of Drosophila and Yeast Ipl1 by Kimura, M, Kotani, S, Hattori, T, Sumi, N, Yoshioka, T, Todokoro, K, Okano, Y

“…Mutations in Aurora of Drosophila and related Saccharomyces cerevisiae Ipl1 kinase are known to cause abnormal chromosome segregation. We have isolated a cDNA…”
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Protective Action of Indapamide, a Thiazide-Like Diuretic, on Ischemia-Induced Injury and Barrier Dysfunction in Mouse Brain Microvascular Endothelial Cells by Nishioku, Tsuyoshi, Takata, Fuyuko, Yamauchi, Atsushi, Sumi, Noriko, Yamamoto, Ikumi, Fujino, Akiko, Naito, Mikihiko, Tsuruo, Takashi, Shuto, Hideki, Kataoka, Yasufumi

“…The aim of the present study was to elucidate the effects of indapamide on ischemic damage to the blood-brain barrier (BBB) in vitro. The ischemia /reperfusion…”
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Activation of p38 Mitogen-Activated Protein Kinase and Caspases in UVB-Induced Apoptosis of Human Keratinocyte HaCaT Cells by Shimizu, Hideki, Kitajima, Yasuo, Banno, Yoshiko, Sumi, Noriko, Naganawa, Takashi, Nozawa, Yoshinori

“…Exposure of human keratinocyte HaCaT cells to ultraviolet B-irradiation induced apoptotic morphologic changes. In this study, we found that the ultraviolet B…”
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Inhibition of transforming growth factor-beta production in brain pericytes contributes to cyclosporin A-induced dysfunction of the blood-brain barrier by Takata, Fuyuko, Dohgu, Shinya, Yamauchi, Atsushi, Sumi, Noriko, Nakagawa, Shinsuke, Naito, Mikihiko, Tsuruo, Takashi, Shuto, Hideki, Kataoka, Yasufumi

“…: 1. The present study was designed to clarify whether brain pericytes and pericyte-derived transforming growth factor-beta1 (TGF-beta1) participate in…”
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Adverse effect of cyclosporin A on barrier functions of cerebral microvascular endothelial cells after hypoxia-reoxygenation damage in vitro by Dohgu, Shinya, Nishioku, Tsuyoshi, Sumi, Noriko, Takata, Fuyuko, Nakagawa, Shinsuke, Naito, Mikihiko, Tsuruo, Takashi, Yamauchi, Atsushi, Shuto, Hideki, Kataoka, Yasufumi

“…Hypoxia and post-hypoxic reoxygenation induces disruption of the blood-brain barrier (BBB). Alterations of the BBB function after hypoxia/reoxygenation (H/R)…”
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Tumor Necrosis Factor-α Mediates the Blood-Brain Barrier Dysfunction Induced by Activated Microglia in Mouse Brain Microvascular Endothelial Cells by Tsuyoshi Nishioku, Junichi Matsumoto, Shinya Dohgu, Noriko Sumi, Kenji Miyao, Fuyuko Takata, Hideki Shuto, Atsushi Yamauchi, Yasufumi Kataoka

“…The present study was designed to elucidate the involvement of tumor necrosis factor α(TNF-α) release from activated microglia in the induction of blood-brain…”
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P1O-P3-5 Involvement of the activated microglia in the blood-brain barrier breakdown induced by lipopolysaccharide by Junichi Matsumoto, Noriko Sumi, Tsuyoshi Nishioku, Shinya Dohgu, Shinsuke Nakagawa, Atsushi Yamauchi, Hideki Shuto, Masami Niwa, Yasufumi Kataoka

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Lipopolysaccharide-Activated Microglia Induce Dysfunction of the Blood-Brain Barrier in Rat Microvascular Endothelial Cells Co-Cultured with Microglia by Sumi, Noriko, Nishioku, Tsuyoshi, Takata, Fuyuko, Matsumoto, Junichi, Watanabe, Takuya, Shuto, Hideki, Yamauchi, Atsushi, Dohgu, Shinya, Kataoka, Yasufumi

“…The blood-brain barrier (BBB) is formed by brain capillary endothelial cells, astrocytes, pericytes, microglia, and neurons. BBB disruption under pathological…”
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P1I-12 Involvement of the activated microglia in the induction of blood-brain barrier dysfunction by Noriko Sumi, Tsuyoshi Nishioku, Kotoe Asano, Junichi Matsumoto, Shinsuke Nakagawa, Atsushi Yamauchi, Hideki Shuto, Masami Niwa, Yasufumi Kataoka

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P1I-13 Time-course of morphological alterations of pericytes in the blood-brain barrier disruption by Naoko Ishikawa, Tsuyoshi Nishioku, Noriko Sumi, Hiromi Nakanishi, Atsushi Yamauchi, Shinsuke Nakagawa, Hideki Shuto, Masami Niwa, Yasufumi Kataoka

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P2-019 Protective effect of adrenomedullin on lipopolysaccharide-induced blood-brain barrier dysfunction by Noriko Sumi, Tsuyoshi Nishioku, Fuyuko Takata, Atsushi Yamauchi, Shinsuke Nakagawa, Maria A Deli, Hideki Shuto, Masami Niwa, Yasufumi Kataoka

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P2-018 Involvement of microglia in the induction of blood-brain barrier dysfunction by Kenji Miyao, Tsuyoshi Nishioku, Fuyuko Takata, Noriko Sumi, Atsushi Yamauchi, Shinsuke Nakagawa, Maria A Deli, Hideki Shuto, Masami Niwa, Yasufumi Kataoka

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P2-021 Relaxation of cultured rat brain pericytes after stimulation with adrenomedullin by Hiroyuki Takahashi, Fuyuko Takata, Tsuyoshi Nishioku, Atsushi Yamauchi, Noriko Sumi, Shinsuke Nakagawa, Maria A Deli, Hideki Shuto, Masami Niwa, Yasufumi Kataoka

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RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer by Shibata, K, Itoh, M, Aizawa, K, Nagaoka, S, Sasaki, N, Carninci, P, Konno, H, Akiyama, J, Nishi, K, Kitsunai, T, Tashiro, H, Sumi, N, Ishii, Y, Nakamura, S, Hazama, M, Nishine, T, Harada, A, Yamamoto, R, Matsumoto, H, Sakaguchi, S, Ikegami, T, Kashiwagi, K, Fujiwake, S, Inoue, K, Togawa, Y

“…The RIKEN high-throughput 384-format sequencing pipeline (RISA system) including a 384-multicapillary sequencer (the so-called RISA sequencer) was developed…”
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The brain pericyte-derived transforming growth factor-beta (TGF-β) upregulates the blood-brain barrier function by Fuyuko Takata, Shinya Dohgu, Atsushi Yamauchi, Noriko Sumi, Shinsuke Nakagawa, Masami Niwa, Yasufumi Kataoka

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Cyclosporin A induces dysfunction of the blood-brain barrier by inhibiting adrenomedullin signal transduction in mouse brain endothelial cells by Noriko Sumi, Shinya Dohgu, Atsushi Yamauchi, Fuyuko Takata, Shinsuke Nakagawa, Masami Niwa, Yasufumi Kataoka

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