Search Results - "Nordbrock, E"
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Dose-titration, multicenter study of oral transmucosal fentanyl citrate for the treatment of breakthrough pain in cancer patients using transdermal fentanyl for persistent pain
Published in Journal of clinical oncology (01-10-1998)“…Supplemental, "as-needed," administration of an opioid is a common approach to the problem of breakthrough pain in cancer patients. Oral transmucosal fentanyl…”
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Single and multiple oral dose pharmacokinetics of clentiazem in normal volunteers
Published in Journal of clinical pharmacology (01-05-1993)“…This study was designed to determine the pharmacokinetics and dose proportionality of clentiazem (CLZ) after single doses (SD) of 20, 40, and 80 mg and…”
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Oral transmucosal fentanyl citrate : Randomized, double-blinded, placebo-controlled trial for treatment of breakthrough pain in cancer Patients
Published in JNCI : Journal of the National Cancer Institute (15-04-1998)“…Patients with cancer frequently experience episodes of acute pain, i.e., breakthrough pain, superimposed on their chronic pain. Breakthrough pain is usually…”
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Oral transmucosal fentanyl citrate (OTFC) for the treatment of breakthrough pain in cancer patients: a controlled dose titration study
Published in Pain (Amsterdam) (01-02-1999)“…Oral transmucosal fentanyl citrate (OTFC) is a novel opioid formulation in which the potent synthetic mu-agonist fentanyl is embedded in a sweetened matrix…”
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The relative potency of oral transmucosal fentanyl citrate compared with intravenous morphine in the treatment of moderate to severe postoperative pain
Published in Anesthesia and analgesia (01-09-1999)“…Pharmacokinetic studies have shown that oral transmucosal absorption of fentanyl is relatively rapid compared with gastrointestinal absorption, and it results…”
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Statistical comparison of stability study designs
Published in Journal of biopharmaceutical statistics (1992)“…Studies are routinely conducted during development of a new drug to investigate the effect of strength, package, batch, storage condition, and storage time on…”
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Oral transmucosal etomidate in volunteers
Published in Anesthesiology (Philadelphia) (1998)“…The oral transmucosal route of delivery is now used for many drugs, including fentanyl and midazolam. Etomidate's pharmacokinetic profile and physiochemical…”
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Population pharmacokinetics of teicoplanin in patients with endocarditis
Published in Journal of pharmacokinetics and biopharmaceutics (01-02-1995)“…Teicoplanin is a new glycopeptide antibiotic, active against aerobic and anaerobic gram-positive bacteria. The drug is intended for the treatment of systemic…”
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A comparison of two measures of quality-of life for congestive heart failure
Published in Journal of cardiac failure (01-09-1998)Get full text
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