Search Results - "Nordblom, Gerald D."

Cross-reactivity of fosphenytoin in two human plasma phenytoin immunoassays by Kugler, Alan R, Annesley, Thomas M, Nordblom, Gerald D, Koup, Jeffrey R, Olson, Stephen C

“…The cross-reactivity of fosphenytoin, a phosphate ester prodrug of phenytoin, was investigated in the Abbott phenytoin TDx/TDxFLx fluorescence polarization…”
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On-Probe Immunoaffinity Extraction by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry by Liang, Xiaoli, Lubman, David M, Rossi, David T, Nordblom, Gerald D, Barksdale, Charles M

“…A simple and effective method has been proposed in this work for combination of immunoaffinity extraction with MALDI MS. In this method, an antibody is…”
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Synthesis of N-desmethyl PNQX: elaboration into an immunogenic conjugate and a radioiodinated ligand; radioimmunoassay for the AMPA/NMDA antagonist, PNQX by Bigge, Christopher F, Stephen Yi, C, Nordblom, Gerald D

“…A nine-step synthesis of N-desmethyl PNQX 5 and its subsequent elaboration into analogs, a porcine thyroglobulin immunogenic conjugate 8, and a radioiodinated…”
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Clinical pharmacokinetics and relative bioavailability of oral procaterol by ELDON, M. A, BATTLE, M. M, COON, M. J, NORDBLOM, G. D, SEDMAN, A. J, COLBURN, W. A

“…The pharmacokinetics and relative oral bioavailability of procaterol, an orally active beta 2-adrenergic agonist bronchodilator were evaluated in healthy…”
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Workshop on bioanalytical methods validation for macromolecules: summary report by Miller, K J, Bowsher, R R, Celniker, A, Gibbons, J, Gupta, S, Lee, J W, Swanson, S J, Smith, W C, Weiner, R S

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Development of a radioimmunoassay for the anthrapyrazole chemotherapy agent CI-937 and the pharmacokinetics of CI-937 in rats by NORDBLOM, G. D, PACHLA, L. A, TSUNG CHANG, WHITFIELD, L. R, SHOWALTER, H. D. H

“…The anthracyclines daunorubicin and doxorubicin are cancer chemotherapy agents that complex DNA and are widely utilized clinically. Cumulative cardiotoxicity,…”
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Clinical pharmacokinetics of procaterol: dose proportionality after administration of single oral doses by Eldon, M A, Blake, D S, Coon, M J, Nordblom, G D, Sedman, A J, Colburn, W A

“…Procaterol is a potent, orally active beta 2-agonist bronchodilator useful in the treatment of reversible bronchospastic disease. It is effective when…”
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Photoreduction of 4,4'-dichlorobiphenyl by Nordblom, Gerald D, Miller, Larry L

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Photochemistry of N-(.alpha.-trichloromethyl-p-methoxybenzyl)-p-methoxyaniline by Miller, Larry L, Nordblom, Gerald D, Yost, Gregory A

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Sensitized photolyses of DDT and decyl bromide by Miller, Larry L, Narang, Raginder S, Nordblom, Gerald D

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Glucuronidation of Prodrug Reactive Site: Isolation and Characterization of Oxymethylglucuronide Metabolite of Fosphenytoin by Annesley, Thomas M, Kurzyniec, Stephen, Nordblom, Gerald D, Buchanan, Nathan, Pool, William, Reily, Michael, Talaat, Rasmy, Roberts, William L

“…This investigation was undertaken to identify the structure of a novel immunoreactive metabolite derived from fosphenytoin that has been hypothesized…”
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Elucidation of peptide metabolism by on-line immunoaffinity liquid chromatography mass spectrometry by Zheng, Kefei, Lubman, David M., Rossi, David T., Nordblom, Gerald D., Barksdale, Charles M.

“…An immunoaffinity chromatography extraction capillary liquid chromatography separation has been coupled to electrospray ionization mass spectrometry for…”
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Immunochemical Evidence for Induction of the Alcohol-Oxidizing Cytochrome P-450 of Rabbit Liver Microsomes by Diverse Agents: Ethanol, Imidazole, Trichloroethylene, Acetone, Pyrazole, and Isoniazid by Koop, Dennis R., Crump, Becky L., Nordblom, Gerald D., Coon, Minor J.

“…Isozyme 3a of rabbit liver microsomal cytochrome P-450, also termed P-450ALC, was previously isolated in this laboratory from animals administered ethanol or…”
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Perturbation of epidermal growth factor clearance after radioiodination and its implications by Kuo, B S, Nordblom, G D, Wright, D S

“…The clearance of human epidermal growth factor (hEGF1-53) has been thought to be mediated mainly by a high-capacity receptor system, yet relatively low in vivo…”
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Immunochemical evidence for a role of cytochrome P-450 in liver microsomal ethanol oxidation by Koop, D R, Nordblom, G D, Coon, M J

“…Antibodies to cytochrome P-450 isozyme 3a, the ethanol-inducible isozyme in rabbit liver, were used to determine the role of this enzyme in the microsomal…”
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Development and validation of two solid-phase enzyme immunoassays (ELISA) for quantitation of human epidermal growth factors (hEGFs) by SIZEMORE, N, DUDECK, R. C, BARKSDALE, C. M, NORDBLOM, G. D, MUELLER, W. T, MCCONNELL, P, WRIGHT, D. S, GUGLIETTA, A, KUO, B.-S

“…The purpose of the present investigation was to develop and validate two separate enzyme-linked immunosorbent assays (ELISA) for quantitation of exogenous…”
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Hydrogen peroxide formation and stoichiometry of hydroxylation reactions catalyzed by highly purified liver microsomal cytochrome P-450 by Nordblom, G D, Coon, M J

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Disposition kinetics of human epidermal growth factor (hEGF1-53) and its truncated fragment (hEGF1-48) in rats by Kuo, B S, Nordblom, G D, Dudeck, R C, Kirkish, L S, Wright, D S

“…Clearance of human epidermal growth factor (hEGF1-53) has been proposed to be mediated by a receptor pathway involving a typical cascade of ligand-receptor…”
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Studies on hydroperoxide-dependent substrate hydroxylation by purified liver microsomal cytochrome P-450 by Nordblom, G D, White, R E, Coon, M J

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Pharmacokinetics and pharmacodynamics of CI-992 following intravenous and oral administration to cynomolgus monkeys by Cook, Jack A., Burger, Paula J., Michniewicz, Barbara M., Nordblom, Gerald D., Hicks, Gary W., Kaplan, Charles, Ryan, Michael J.

“…The purpose of this study was to characterize CI‐992 pharmacokinetics and pharmacokinetics/pharmacodynamics (PK/PD) in sodium deplete monkeys. Panels of…”
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