Five‐year mortality in patients treated for severe community‐acquired pneumonia – a retrospective study

Background The mortality rate in patients with severe community‐acquired pneumonia (SCAP) is high. We investigated the 5‐year mortality rate and causes of death in a patient population treated for SCAP in our intensive care unit (ICU), and compared the mortality rate in patients with or without chro...

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Published in:	Acta anaesthesiologica Scandinavica Vol. 61; no. 4; pp. 418 - 426
Main Authors:	Lenz, H., Norby, G. O., Dahl, V., Ranheim, T. E., Haagensen, R. E.
Format:	Journal Article
Language:	English
Published:	England Wiley Subscription Services, Inc 01-04-2017
Subjects:	Adult Aged Aged, 80 and over Cardiovascular Diseases - mortality Cause of Death Chronic obstructive pulmonary disease Community-Acquired Infections - mortality Comorbidity Critical Care - statistics & numerical data Diabetes Complications - mortality Female Humans Male Middle Aged Mortality Norway - epidemiology Pneumonia Pneumonia - mortality Pulmonary Disease, Chronic Obstructive - mortality Respiration, Artificial Retrospective Studies Risk Factors
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Summary:	Background The mortality rate in patients with severe community‐acquired pneumonia (SCAP) is high. We investigated the 5‐year mortality rate and causes of death in a patient population treated for SCAP in our intensive care unit (ICU), and compared the mortality rate in patients with or without chronic obstructive pulmonary disease (COPD) as comorbidity. Methods This retrospective study, which covers a period of 10 years, included patients aged > 18 years admitted to our ICU with SCAP as primary diagnosis and in need of mechanical ventilation for more than 24 h. Data were collected from the ICU internal database and the patients' medical records. The times of death were collected from the Norwegian National Registry, and the causes of death from the Norwegian Cause of Death Registry. Results Hundred and seventy three patients were included in the study. The 5‐year mortality rate for the total study population was 57.2%. There were no significant differences in the mortality rate between the group with COPD and the group without COPD (61.2% vs. 54.7%, P = 0.43). There was a wide range of comorbidities. The most common were COPD, myocardial infarction and diabetes mellitus. The two main causes of death after discharge were COPD (17 deaths) and cardiovascular diseases (seven deaths). Conclusions The 5‐year mortality rate of the study population was high (57.2%). COPD did not seem to be a risk factor for mortality compared to non‐COPD patients. The most common causes of death after discharge were COPD and cardiovascular diseases.
Bibliography:	Harald Lenz has a 20% postdoc position funded by Oslo University Hospital, Division of Emergencies and Critical Care, Department of Research and Development, Oslo, Norway Financial support and conflicts of interest ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0001-5172 1399-6576
DOI:	10.1111/aas.12863