Search Results - "Nor, Carolina"

Leading medulloblastoma to a differentiation end by Nör, Carolina, Ramaswamy, Vijay

“…Effective and less toxic therapies for medulloblastoma have proved to be highly elusive. In this issue of Cancer Cell, Yang et al. show that thyroid hormone…”
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Characterization of tumorigenic cell lines from the recurrence and lymph node metastasis of a human salivary mucoepidermoid carcinoma by Warner, Kristy A, Adams, April, Bernardi, Lisiane, Nor, Carolina, Finkel, Kelsey A, Zhang, Zhaocheng, McLean, Scott A, Helman, Joseph, Wolf, Gregory T, Divi, Vasu, Queimado, Lurdes, Kaye, Frederic J, Castilho, Rogerio M, Nör, Jacques E

“…Summary The long-term outcome of patients with mucoepidermoid carcinoma is poor. Limited availability of cell lines and lack of xenograft models is considered…”
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Piecing together the Pediatric Brain Tumor Puzzle by Nör, Carolina, Ramaswamy, Vijay

“…A recent study by Petralia et al. of 218 pediatric brain tumors across seven different entities applied an integrated approach incorporating proteomics,…”
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Next-Generation Profiling of Medulloblastoma: Old Drugs Are an Elegant Weapon in a Civilized Age by Nör, Carolina, Ramaswamy, Vijay

“…Personalized therapies have remained elusive in medulloblastoma, resulting in treatment paradigms that have been largely stagnant for almost four decades. A…”
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Cisplatin Induces Bmi-1 and Enhances the Stem Cell Fraction in Head and Neck Cancer by Nör, Carolina, Zhang, Zhaocheng, Warner, Kristy A, Bernardi, Lisiane, Visioli, Fernanda, Helman, Joseph I, Roesler, Rafael, Nör, Jacques E

“…Abstract Recent evidence has unveiled a subpopulation of highly tumorigenic, multipotent cells capable of self-renewal in head and neck squamous cell…”
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Targeting the epigenome of cancer stem cells in pediatric nervous system tumors by Freire, Natália Hogetop, Jaeger, Mariane da Cunha, de Farias, Caroline Brunetto, Nör, Carolina, Souza, Barbara Kunzler, Gregianin, Lauro, Brunetto, André Tesainer, Roesler, Rafael

“…Medulloblastoma, neuroblastoma, and pediatric glioma account for almost 30% of all cases of pediatric cancers. Recent evidence indicates that pediatric nervous…”
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HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in Medulloblastoma by da Cunha Jaeger, Mariane, Ghisleni, Eduarda Chiesa, Cardoso, Paula Schoproni, Siniglaglia, Marialva, Falcon, Tiago, Brunetto, André T., Brunetto, Algemir L., de Farias, Caroline Brunetto, Taylor, Michael D., Nör, Carolina, Ramaswamy, Vijay, Roesler, Rafael

“…Medulloblastoma (MB), which originates from embryonic neural stem cells (NSCs) or neural precursors in the developing cerebellum, is the most common malignant…”
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Possible mechanisms and biomarkers of resistance to vismodegib in SHH medulloblastoma by Roesler, Rafael, de Farias, Caroline Brunetto, Brunetto, André T, Gregianin, Lauro, Jaeger, Mariane, Nör, Carolina, Thomaz, Amanda

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Endothelial Interleukin‐6 Defines the Tumorigenic Potential of Primary Human Cancer Stem Cells by Krishnamurthy, Sudha, Warner, Kristy A., Dong, Zhihong, Imai, Atsushi, Nör, Carolina, Ward, Brent B., Helman, Joseph I., Taichman, Russell S., Bellile, Emily L., McCauley, Laurie K., Polverini, Peter J., Prince, Mark E., Wicha, Max S., Nör, Jacques E.

“…Head and neck squamous cell carcinomas (HNSCC) contain a small subpopulation of stem cells endowed with unique capacity to generate tumors. These cancer stem…”
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Histone Deacetylase Inhibitors in Pediatric Brain Cancers: Biological Activities and Therapeutic Potential by Perla, Alexandre, Fratini, Lívia, Cardoso, Paula S., Nör, Carolina, Brunetto, André T., Brunetto, Algemir L., de Farias, Caroline Brunetto, Jaeger, Mariane, Roesler, Rafael

“…Brain cancers are the leading cause of cancer-related deaths in children. Biological changes in these tumors likely include epigenetic deregulation during…”
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Radicular Cyst: An Update of the Biological Factors Related to Lining Epithelium by Bernardi, Lisiane, DDS, PhD, Visioli, Fernanda, DDS, PhD, Nör, Carolina, BPharm, PhD, Rados, Pantelis Varvaki, DDS, PhD

“…Abstract Introduction Radicular cysts are common lesions in daily dentistry practice. However, the mechanisms related to epithelial lining formation and cavity…”
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Propolis reduces the stemness of head and neck squamous cell carcinoma by Nör, Felipe, Nör, Carolina, Bento, Letícia W., Zhang, Zhaocheng, Bretz, Walter A., Nör, Jacques E.

“…•Cancer stem cells are associated with tumor progression and resistance to therapy.•Propolis is cytotoxic to head and neck squamous cell carcinoma…”
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Neurotrophin Signaling in Medulloblastoma by Thomaz, Amanda, Jaeger, Mariane, Brunetto, Algemir L, Brunetto, André T, Gregianin, Lauro, de Farias, Caroline Brunetto, Ramaswamy, Vijay, Nör, Carolina, Taylor, Michael D, Roesler, Rafael

“…Neurotrophins are a family of secreted proteins that act by binding to tropomyosin receptor kinase (Trk) or p75NTR receptors to regulate nervous system…”
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Photobiomodulation regulates cytokine release and new blood vessel formation during oral wound healing in rats by Wagner, Vivian Petersen, Curra, Marina, Webber, Liana Preto, Nör, Carolina, Matte, Ursula, Meurer, Luise, Martins, Manoela Domingues

“…The aim of the present study was to evaluate the effects of photobiomodulation (PBM) on cytokine levels and angiogenesis during oral wound healing. Ulcers were…”
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Combined MEK and JAK/STAT3 pathway inhibition effectively decreases SHH medulloblastoma tumor progression by Zagozewski, Jamie, Borlase, Stephanie, Guppy, Brent J., Coudière-Morrison, Ludivine, Shahriary, Ghazaleh M., Gordon, Victor, Liang, Lisa, Cheng, Stephen, Porter, Christopher J., Kelley, Rhonda, Hawkins, Cynthia, Chan, Jennifer A., Liang, Yan, Gong, Jingjing, Nör, Carolina, Saulnier, Olivier, Wechsler-Reya, Robert J., Ramaswamy, Vijay, Werbowetski-Ogilvie, Tamra E.

“…Medulloblastoma (MB) is the most common primary malignant pediatric brain cancer. We recently identified novel roles for the MEK/MAPK pathway in regulating…”
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Antitumor Activities and Cellular Changes Induced by TrkB Inhibition in Medulloblastoma by Thomaz, Amanda, Pinheiro, Kelly de Vargas, Souza, Bárbara Kunzler, Gregianin, Lauro, Brunetto, Algemir L, Brunetto, André T, de Farias, Caroline Brunetto, Jaeger, Mariane da Cunha, Ramaswamy, Vijay, Nör, Carolina, Taylor, Michael D, Roesler, Rafael

“…Neurotrophins are critically involved in regulating normal neural development and plasticity. Brain-derived neurotrophic factor (BDNF), a neurotrophin that…”
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A clinically compatible drug‐screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis by Zhu, Lucía, Retana, Diana, García‐Gómez, Pedro, Álvaro‐Espinosa, Laura, Priego, Neibla, Masmudi‐Martín, Mariam, Yebra, Natalia, Miarka, Lauritz, Hernández‐Encinas, Elena, Blanco‐Aparicio, Carmen, Martínez, Sonia, Sobrino, Cecilia, Ajenjo, Nuria, Artiga, Maria‐Jesus, Ortega‐Paino, Eva, Torres‐Ruiz, Raúl, Rodríguez‐Perales, Sandra, Soffietti, Riccardo, Bertero, Luca, Cassoni, Paola, Weiss, Tobias, Muñoz, Javier, Sepúlveda, Juan Manuel, González‐León, Pedro, Jiménez‐Roldán, Luis, Moreno, Luis Miguel, Esteban, Olga, Pérez‐Núñez, Ángel, Hernández‐Laín, Aurelio, Toldos, Oscar, Ruano, Yolanda, Alcázar, Lucía, Blasco, Guillermo, Fernández‐Alén, José, Caleiras, Eduardo, Lafarga, Miguel, Megías, Diego, Graña‐Castro, Osvaldo, Nör, Carolina, Taylor, Michael D, Young, Leonie S, Varešlija, Damir, Cosgrove, Nicola, Couch, Fergus J, Cussó, Lorena, Desco, Manuel, Mouron, Silvana, Quintela‐Fandino, Miguel, Weller, Michael, Pastor, Joaquín, Valiente, Manuel, de la Lama‐Zaragoza, Adolfo, Calero‐Felix, Lourdes, Fiaño‐Valverde, Concepcion, Delgado‐López, Pedro David, Montalvo‐Afonso, Antonio, Pascual‐Llorente, Mar, Díaz‐Piqueras, Ángela, Nam‐Cha, SH, Barrena López, Cristina, Plans Ahicart, Gerard, Martínez‐Saez, Elena, Ramón y Cajal, Santiago, Nicolás, Pilar

“…We report a medium‐throughput drug‐screening platform (METPlatform) based on organotypic cultures that allows to evaluate inhibitors against metastases growing…”
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Gastrin-releasing peptide and its receptor increase arthritis fibroblast-like synoviocytes invasiveness through activating the PI3K/AKT pathway by Clarimundo, Vanessa Schuck, Farinon, Mirian, Pedó, Renata Ternus, Teixeira, Vivian Oliveira Nunes, Nör, Carolina, Gulko, Percio S., Xavier, Ricardo Machado, de Oliveira, Patricia Gnieslaw

“…•Fibroblast-like synoviocytes express gastrin-releasing receptor protein.•GRP increased FLS invasiveness and RC-3095 reverse that effect.•The effect of GRP…”
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BIOL-08. RADIATION DRIVES METASTASIS IN MEDULLOBLASTOMA THROUGH AN INFLAMMATORY PROCESS by Nor, Carolina, Kharas, Kaitlin, Rasnitsyn, Alexandra, Vladoiu, Maria, Ramaswamy, Vijay, Raleigh, David, Taylor, Michael

“…Abstract Current treatment for medulloblastoma is comprised of surgery, radiotherapy (RT) and/or chemotherapy. Although the primary tumor is controlled with…”
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Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma by Donovan, Laura K., Delaidelli, Alberto, Joseph, Sujith K., Bielamowicz, Kevin, Fousek, Kristen, Holgado, Borja L., Manno, Alex, Srikanthan, Dilakshan, Gad, Ahmed Z., Van Ommeren, Randy, Przelicki, David, Richman, Cory, Ramaswamy, Vijay, Daniels, Craig, Pallota, Jonelle G., Douglas, Tajana, Joynt, Alyssa C. M., Haapasalo, Joonas, Nor, Carolina, Vladoiu, Maria C., Kuzan-Fischer, Claudia M., Garzia, Livia, Mack, Stephen C., Varadharajan, Srinidhi, Baker, Matthew L., Hendrikse, Liam, Ly, Michelle, Kharas, Kaitlin, Balin, Polina, Wu, Xiaochong, Qin, Lei, Huang, Ning, Stucklin, Ana Guerreiro, Morrissy, A. Sorana, Cavalli, Florence M. G., Luu, Betty, Suarez, Raul, De Antonellis, Pasqualino, Michealraj, Antony, Rastan, Avesta, Hegde, Meenakshi, Komosa, Martin, Sirbu, Olga, Kumar, Sachin A., Abdullaev, Zied, Faria, Claudia C., Yip, Stephen, Hukin, Juliette, Tabori, Uri, Hawkins, Cynthia, Aldape, Ken, Daugaard, Mads, Maris, John M., Sorensen, Poul H., Ahmed, Nabil, Taylor, Michael D.

“…Recurrent medulloblastoma and ependymoma are universally lethal, with no approved targeted therapies and few candidates presently under clinical evaluation…”
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