Search Results - "Noori, Hamid R"
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Largely overlapping neuronal substrates of reactivity to drug, gambling, food and sexual cues: A comprehensive meta-analysis
Published in European neuropsychopharmacology (01-09-2016)“…Abstract Cue reactivity to natural and social rewards is essential for motivational behavior. However, cue reactivity to drug rewards can also elicit craving…”
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Activation of Melatonin Receptors Reduces Relapse-Like Alcohol Consumption
Published in Neuropsychopharmacology (New York, N.Y.) (01-12-2015)“…Melatonin is an endogenous synchronizer of biological rhythms and a modulator of physiological functions and behaviors of all mammals. Reduced levels of…”
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Convergent evidence from alcohol-dependent humans and rats for a hyperdopaminergic state in protracted abstinence
Published in Proceedings of the National Academy of Sciences - PNAS (15-03-2016)“…A major hypothesis in addiction research is that alcohol induces neuroadaptations in the mesolimbic dopamine (DA) system and that these neuroadaptations…”
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Intensive longitudinal characterization of multidimensional biobehavioral dynamics in laboratory rats
Published in Cell reports (Cambridge) (13-04-2021)“…Rats have been used as animal models for human diseases for more than a century, yet a systematic understanding of basal biobehavioral phenotypes of laboratory…”
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A multiscale cerebral neurochemical connectome of the rat brain
Published in PLoS biology (03-07-2017)“…Understanding the rat neurochemical connectome is fundamental for exploring neuronal information processing. By using advanced data mining, supervised machine…”
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The Use of a Novel Drinkometer System for Assessing Pharmacological Treatment Effects on Ethanol Consumption in Rats
Published in Alcoholism, clinical and experimental research (01-01-2013)“…Background There are numerous studies in the preclinical alcohol research field showing that pharmacological interventions and many other manipulations can…”
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Systemic neurotransmitter responses to clinically approved and experimental neuropsychiatric drugs
Published in Nature communications (08-11-2018)“…Neuropsychiatric disorders are the third leading cause of global disease burden. Current pharmacological treatment for these disorders is inadequate, with…”
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Inhibition of the casein-kinase-1-ε/δ/ prevents relapse-like alcohol drinking
Published in Neuropsychopharmacology (New York, N.Y.) (01-08-2012)“…During the past decade, it has been shown that circadian clock genes have more than a simple circadian time-keeping role. Clock genes also modulate…”
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Towards trans-diagnostic mechanisms in psychiatry: neurobehavioral profile of rats with a loss-of-function point mutation in the dopamine transporter gene
Published in Disease models & mechanisms (01-04-2017)“…The research domain criteria (RDoC) matrix has been developed to reorient psychiatric research towards measurable behavioral dimensions and underlying…”
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Stress and alcohol interactions: animal studies and clinical significance
Published in Trends in neurosciences (Regular ed.) (01-04-2014)“…Highlights • Stress-induced alcohol consumption is age-dependent. • Interactions between stress and reward systems drive stress-induced drinking. •…”
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The impact of acetylcholinesterase inhibitors on the extracellular acetylcholine concentrations in the adult rat brain: A meta-analysis
Published in Synapse (New York, N.Y.) (01-10-2012)“…In vivo microdialysis has become a key method in investigating the dynamics of different neurotransmitter systems such as acetylcholine in the extracellular…”
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Adaptive dynamics of the 5‐HT systems following chronic administration of selective serotonin reuptake inhibitors: a meta‐analysis
Published in Journal of neurochemistry (01-09-2017)“…Selective serotonin reuptake inhibitors (SSRIs) are the most frequently prescribed antidepressants. However, a major concern is their delayed onset of action,…”
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Neural substrates of sexual arousal are not sex dependent
Published in Proceedings of the National Academy of Sciences - PNAS (30-07-2019)“…Sexual arousal is a dynamical, highly coordinated neurophysiological process that is often induced by visual stimuli. Numerous studies have proposed that the…”
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No basal or drug‐induced sex differences in striatal dopaminergic levels: a cluster and meta‐analysis of rat microdialysis studies
Published in Journal of neurochemistry (01-02-2020)“…Sex differences in behavioural patterns of drug abuse and dependence have been hypothesized to be a consequence of sexual dimorphisms in brain pathways,…”
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Cluster and meta-analyses on factors influencing stress-induced alcohol drinking and relapse in rodents
Published in Addiction biology (01-03-2014)“…Numerous preclinical studies have focused on the identification of biological and environmental factors that modulate stress and alcohol interactions. Although…”
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Early detection and monitoring of cerebral ischemia using calcium-responsive MRI probes
Published in Proceedings of the National Academy of Sciences - PNAS (08-10-2019)“…Cerebral ischemia is one of the leading causes of mortality and disability in infants and adults and its timely diagnosis is essential for an efficient…”
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Dopamine and opioid systems adaptation in alcoholism revisited: Convergent evidence from positron emission tomography and postmortem studies
Published in Neuroscience and biobehavioral reviews (01-11-2019)“…•A hypodopaminergic model is commonly proposed to underly relapse to alcohol drinking.•Addiction leads to highly dynamic changes in dopamine and opioid…”
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Addiction Research Consortium: Losing and regaining control over drug intake (ReCoDe)—From trajectories to mechanisms and interventions
Published in Addiction biology (01-03-2020)“…One of the major risk factors for global death and disability is alcohol, tobacco, and illicit drug use. While there is increasing knowledge with respect to…”
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Neurocircuitry for modeling drug effects
Published in Addiction biology (01-09-2012)“…The identification and functional understanding of the neurocircuitry that mediates alcohol and drug effects that are relevant for the development of addictive…”
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