Search Results - "Noordin, Mohamed Ibrahim"
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Hydrogel polysaccharides of tamarind and xanthan to formulate hydrodynamically balanced matrix tablets of famotidine
Published in Molecules (Basel, Switzerland) (05-09-2014)“…The gastroretentive dosage form of famotidine was modified using tamarind seed powders to prolong the gastric retention time. Tamarind seeds were used in two…”
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Koenimbin, a natural dietary compound of Murraya koenigii (L) Spreng: inhibition of MCF7 breast cancer cells and targeting of derived MCF7 breast cancer stem cells (CD44+/CD24-/low): an in vitro study
Published in Drug design, development and therapy (24-02-2015)“…Background: Inhibition of breast cancer stem cells has been shown to be an effective therapeutic strategy for cancer prevention. The aims of this work were to…”
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In vitro and in vivo anti-angiogenic activity of girinimbine isolated from Murraya koenigii
Published in Drug design, development and therapy (01-01-2015)“…Girinimbine is a carbazole alkaloid isolated from the stem bark and root of Murraya koenigii. Here we report that girinimbine is an inhibitor of angiogenic…”
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4
In vitro and in vivo Evaluation of New Topical Anaesthetic Cream Formulated with Palm Oil Base
Published in Current drug delivery (01-01-2017)“…Topical local anaesthetic cream was reported to be useful for pain relief for cutaneous procedures such as minor surgery and venipuncture. The aim of this…”
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5
The Use of Hibiscus esculentus (Okra) Gum in Sustaining the Release of Propranolol Hydrochloride in a Solid Oral Dosage Form
Published in BioMed research international (01-01-2014)“…The effectiveness of Okra gum in sustaining the release of propranolol hydrochloride in a tablet was studied. Okra gum was extracted from the pods of Hibiscus…”
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In Vivo Studies of Nanostructure-Based Photosensitizers for Photodynamic Cancer Therapy
Published in Small (Weinheim an der Bergstrasse, Germany) (29-12-2014)“…Animal models, particularly rodents, are major translational models for evaluating novel anticancer therapeutics. In this review, different types of…”
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Proof-of-Concept of Detection of Counterfeit Medicine through Polymeric Materials Analysis of Plastics Packaging
Published in Polymers (30-06-2021)“…The detection of counterfeit pharmaceuticals is always a major challenge, but the early detection of counterfeit medicine in a country will reduce the fatal…”
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Lectin-functionalized carboxymethylated kappa-carrageenan microparticles for oral insulin delivery
Published in Carbohydrate polymers (15-08-2011)“…We hypothesized that pH-responsive carboxymethylated kappa-carrageenan microparticles could protect entrapped oral insulin from acidic and proteolytic…”
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Evaluation of the glycemic effect of Ceratonia siliqua pods (Carob) on a streptozotocin-nicotinamide induced diabetic rat model
Published in PeerJ (San Francisco, CA) (23-05-2018)“…pods (carob) have been nominated to control the high blood glucose of diabetics. In Yemen, however, its antihyperglycemic activity has not been yet assessed…”
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Carboxymethylation of kappa-carrageenan for intestinal-targeted delivery of bioactive macromolecules
Published in Carbohydrate polymers (01-02-2011)“…The work presented herein discusses the carboxymethylation of kappa-carrageenan, a natural linear polysaccharide, to afford a pH-dependent swelling property…”
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11
Development and Characterization of Liposomal Doxorubicin Hydrochloride with Palm Oil
Published in BioMed research international (01-01-2014)“…The usage of natural products in pharmaceuticals has steadily seen improvements over the last decade, and this study focuses on the utilization of palm oil in…”
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12
Formulation and in vitro, in vivo evaluation of effervescent floating sustained-release imatinib mesylate tablet
Published in PloS one (02-06-2015)“…Imatinib mesylate is an antineoplastic agent which has high absorption in the upper part of the gastrointestinal tract (GIT). Conventional imatinib mesylate…”
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Antiproliferative effects of imatinib mesylate on ZR‑75‑1 and MDA‑MB‑231 cell lines via PDGFR‑β, PDGF‑BB, c‑Kit and SCF expression
Published in International journal of molecular medicine (01-07-2018)“…Imatinib mesylate is an anti-neoplastic targeted chemotherapeutic agent, which can inhibit tyrosine kinase receptors, including BCR-ABL, platelet-derived…”
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Ultrastructural Study on the Antibacterial Activity of Artonin E versus Streptomycin against Staphylococcus aureus Strains
Published in PloS one (01-06-2015)“…Staphylococci are facultative anaerobes, perfectly spherical un-encapsulated cocci, with a diameter not exceeding 1 micrometer in diameter. Staphylococcus…”
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15
Anticancer and anti-inflammatory activities of girinimbine isolated from Murraya koenigii
Published in Drug design, development and therapy (01-01-2017)“…Therapy that directly targets apoptosis and/or inflammation could be highly effective for the treatment of cancer. is an edible herb that has been…”
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Synergistic effect of quercetin and quinic acid by alleviating structural degeneration in the liver, kidney and pancreas tissues of STZ-induced diabetic rats: A mechanistic study
Published in Food and chemical toxicology (01-09-2014)“…•The present study was to investigate the synergistic effects of QE and QA on STZ-induced diabetic rats.•Combination dose of QE and QA prevents the…”
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Importance and globalization status of good manufacturing practice (GMP) requirements for pharmaceutical excipients
Published in Saudi pharmaceutical journal (01-01-2015)“…Pharmaceutical excipients are no longer inert materials but it is effective and able to improve the characteristics of the products’ quality, stability,…”
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18
Novel swellable polymer of orchidaceae family for gastroretentive drug delivery of famotidine
Published in Drug design, development and therapy (01-01-2014)“…This study aimed to develop hydrophilic, gastroretentive matrix tablets of famotidine with good floating and swelling properties. A novel gastroretentive drug…”
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In vitro and in vivo anti-inflammatory activities of columbin through the inhibition of cycloxygenase-2 and nitric oxide but not the suppression of NF-κB translocation
Published in European journal of pharmacology (05-03-2012)“…Columbin, a diterpenoid furanolactone, was isolated purely for the first time from the plant species Tinspora bakis. The anti-inflammatory effects of columbin…”
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Toxicological Features of Catha edulis (Khat) on Livers and Kidneys of Male and Female Sprague-Dawley Rats: A Subchronic Study
Published in Evidence-based complementary and alternative medicine (01-01-2012)“…Hepato- and nephrotoxicity of Khat consumption (Catha edulis Forskal) have been evoked. Therefore, this study was conducted to evaluate such possible…”
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