Search Results - "Noordhuis, Maartje"

16S rRNA amplicon sequencing identifies microbiota associated with oral cancer, human papilloma virus infection and surgical treatment by Guerrero-Preston, Rafael, Godoy-Vitorino, Filipa, Jedlicka, Anne, Rodríguez-Hilario, Arnold, González, Herminio, Bondy, Jessica, Lawson, Fahcina, Folawiyo, Oluwasina, Michailidi, Christina, Dziedzic, Amanda, Thangavel, Rajagowthamee, Hadar, Tal, Noordhuis, Maartje G, Westra, William, Koch, Wayne, Sidransky, David

“…Systemic inflammatory events and localized disease, mediated by the microbiome, may be measured in saliva as head and neck squamous cell carcinoma (HNSCC)…”
Get full text

OGDHL is a modifier of AKT-dependent signaling and NF-κB function by Sen, Tanusree, Sen, Nilkantha, Noordhuis, Maartje G, Ravi, Rajani, Wu, T-C, Ha, Patrick K, Sidransky, David, Hoque, Mohammad Obaidul

“…Oxoglutarate dehydrogenase (OGDH) is the first and rate-limiting component of the multi-enzyme OGDH complex (OGDHC) whose malfunction is associated with…”
Get full text

High-risk HPV infection-associated hypermethylated genes in oropharyngeal squamous cell carcinomas by Inokawa, Yoshikuni, Hayashi, Masamichi, Begum, Shahnaz, Noordhuis, Maartje G, Sidransky, Daivd, Califano, Joseph, Koch, Wayne, Brait, Mariana, Westra, William H, Hoque, Mohammad O

“…Background HPV-positive oropharyngeal squamous cell carcinomas (OPSCCs) are sensitive to chemo-radiation therapy and have favorable survival outcomes compared…”
Get full text

Key tumor suppressor genes inactivated by "greater promoter" methylation and somatic mutations in head and neck cancer by Guerrero-Preston, Rafael, Michailidi, Christina, Marchionni, Luigi, Pickering, Curtis R, Frederick, Mitchell J, Myers, Jeffrey N, Yegnasubramanian, Srinivasan, Hadar, Tal, Noordhuis, Maartje G, Zizkova, Veronika, Fertig, Elana, Agrawal, Nishant, Westra, William, Koch, Wayne, Califano, Joseph, Velculescu, Victor E, Sidransky, David

“…Tumor suppressor genes (TSGs) are commonly inactivated by somatic mutation and/or promoter methylation; yet, recent high-throughput genomic studies have not…”
Get full text

Prognostic Cell Biological Markers in Cervical Cancer Patients Primarily Treated With (Chemo)radiation: A Systematic Review by Noordhuis, Maartje G., B.Sc, Eijsink, Jasper J.H., M.D, Roossink, Frank, M.Sc, de Graeff, Pauline, M.D., Ph.D, Pras, Elisabeth, M.D., Ph.D, Schuuring, Ed, Ph.D, Wisman, G. Bea A., Ph.D, de Bock, Geertruida H., Ph.D, van der Zee, Ate G.J., M.D., Ph.D

“…The aim of this study was to systematically review the prognostic and predictive significance of cell biological markers in cervical cancer patients primarily…”
Get full text

Expression of Epidermal Growth Factor Receptor (EGFR) and Activated EGFR Predict Poor Response to (Chemo)radiation and Survival in Cervical Cancer by NOORDHUIS, Maartje G, EIJSINK, Jasper J. H, WISMAN, G. Bea A, SCHUURING, Ed, VAN DER ZEE, Ate G. J, TEN HOOR, Klaske A, ROOSSINK, Frank, HOLLEMA, Harry, ARTS, Henriëtte J. G, PRAS, Elisabeth, MADURO, John H, REYNERS, Anna K. L, DE BOCK, Geertruida H

“…Purpose: Activation of the epidermal growth factor receptor (EGFR) signaling pathway has been reported to induce resistance to (chemo)radiation in cancers,…”
Get full text

High pATM is Associated With Poor Local Control in Supraglottic Cancer Treated With Radiotherapy by Bruine de Bruin, Leonie, Schuuring, Ed, Bock, Geertruida H., Slagter‐Menkema, Lorian, Mastik, Mirjam F., Noordhuis, Maartje G., Langendijk, Johannes A., Kluin, Philip M., Laan, Bernard F.A.M.

“…Objectives Most early stage laryngeal squamous cell carcinomas (LSCC) are treated with radiotherapy. Discovery of new biomarkers are needed to improve…”
Get full text

Involvement of the TGF-β and β-Catenin Pathways in Pelvic Lymph Node Metastasis in Early-Stage Cervical Cancer by NOORDHUIS, Maartje G, FEHRMANN, Rudolf S. N, HOLLEMA, Harry, DE VRIES, Elisabeth G. E, DE BOCK, Geertruida H, VAN DER ZEE, Ate G. J, SCHUURING, Ed, WISMAN, G. Bea A, NIJHUIS, Esther R, VAN ZANDEN, Jelmer J, MOERLAND, Perry D, VER LOREN VAN THEMAAT, Emiel, VOLDERS, Haukeline H, KOK, Mirjam, TEN HOOF, Klaske A

“…Presence of pelvic lymph node metastases is the main prognostic factor in early-stage cervical cancer patients, primarily treated with surgery. Aim of this…”
Get full text

Integrated transcriptomic and epigenomic analysis of ovarian cancer reveals epigenetically silenced GULP1 by Maldonado, Leonel, Brait, Mariana, Izumchenko, Evgeny, Begum, Shahnaz, Chatterjee, Aditi, Sen, Tanusree, Loyo, Myriam, Barbosa, Alvaro, Poeta, Maria Luana, Makarev, Eugene, Zhavoronkov, Alex, Fazio, Vito M., Angioli, Roberto, Rabitti, Carla, Ongenaert, Mate, Van Criekinge, Wim, Noordhuis, Maartje G., de Graeff, Pauline, Wisman, G. Bea A., van der Zee, Ate G.J., Hoque, Mohammad O.

“…Many epigenetically inactivated genes involved in ovarian cancer (OC) development and progression remain to be identified. In this study we undertook an…”
Get full text

JAK3 Variant, Immune Signatures, DNA Methylation, and Social Determinants Linked to Survival Racial Disparities in Head and Neck Cancer Patients by Guerrero-Preston, Rafael, Lawson, Fahcina, Rodriguez-Torres, Sebastian, Noordhuis, Maartje G, Pirini, Francesca, Manuel, Laura, Valle, Blanca L, Hadar, Tal, Rivera, Bianca, Folawiyo, Oluwasina, Baez, Adriana, Marchionni, Luigi, Koch, Wayne M, Westra, William H, Kim, Young J, Eshleman, James R, Sidransky, David

“…To inform novel personalized medicine approaches for race and socioeconomic disparities in head and neck cancer, we examined germline and somatic mutations,…”
Get full text

Biological tumor markers associated with local control after primary radiotherapy in laryngeal cancer: A systematic review by Noordhuis, Maartje G., Kop, Emiel A., van der Vegt, Bert, Langendijk, Johannes A., Laan, Bernard F. A. M., Schuuring, Ed, Bock, Geertruida H.

“…Background The choice of treatment in laryngeal cancer is mainly based on tumor stage, post‐treatment morbidity and quality of life. Biological tumor markers…”
Get full text

Association of promoter methylation of VGF and PGP9.5 with ovarian cancer progression by Brait, Mariana, Maldonado, Leonel, Noordhuis, Maartje G, Noordhuis, Maartje, Begum, Shahnaz, Loyo, Myriam, Poeta, Maria Luana, Barbosa, Alvaro, Fazio, Vito M, Angioli, Roberto, Rabitti, Carla, Marchionni, Luigi, de Graeff, Pauline, van der Zee, Ate G J, Wisman, G Bea A, Sidransky, David, Hoque, Mohammad O

“…To elucidate the role of biological and clinical impact of aberrant promoter hypermethylation (PH) in ovarian cancer (OC). PH of PGP9.5, HIC1, AIM1, APC, PAK3,…”
Get full text

Genome-wide methylation profiling and the PI3K-AKT pathway analysis associated with smoking in urothelial cell carcinoma by Brait, Mariana, Munari, Enrico, LeBron, Cynthia, Noordhuis, Maartje G., Begum, Shahnaz, Michailidi, Christina, Gonzalez-Roibon, Nilda, Maldonado, Leonel, Sen, Tanusree, Guerrero-Preston, Rafael, Cope, Leslie, Parrella, Paola, Fazio, Vito Michele, Ha, Patrick K., Netto, George J., Sidransky, David, Hoque, Mohammad O.

“…Urothelial cell carcinoma (UCC) is the second most common genitourinary malignant disease in the USA, and tobacco smoking is the major known risk factor for…”
Get full text

Standardised Ki‐67 proliferation index assessment in early‐stage laryngeal squamous cell carcinoma in relation to local control and survival after primary radiotherapy by Kop, Emiel, Bock, Geertruida H., Noordhuis, Maartje G., Slagter‐Menkema, Lorian, Laan, Bernard F. A. M., Langendijk, Johannes A., Schuuring, Ed, Vegt, Bert

“…Objectives Ambiguous results have been reported on the predictive value of the Ki‐67 proliferation index (Ki‐67 PI) regarding local control (LC) and survival…”
Get full text

The role of ATM and 53BP1 as predictive markers in cervical cancer by Roossink, Frank, Wieringa, Hylke W., Noordhuis, Maartje G., ten Hoor, Klaske A., Kok, Mirjam, Slagter-Menkema, Lorian, Hollema, Harry, de Bock, Geertruida H., Pras, Elisabeth, de Vries, Elisabeth G.E., de Jong, Steven, van der Zee, Ate G.J., Schuuring, Ed, Wisman, G. Bea A., van Vugt, Marcel A.T.M.

“…Treatment of advanced‐stage cervical cancers with (chemo)radiation causes cytotoxicity through induction of high levels of DNA damage. Tumour cells respond to…”
Get full text

Viable tumor in salvage neck dissections in head and neck cancer: Relation with initial treatment, change of lymph node size and human papillomavirus by van den Bovenkamp, Karlijn, Dorgelo, Bart, Noordhuis, Maartje G., van der Laan, Bernard F.A.M., van der Vegt, Bert, Bijl, Hendrik P., Roodenburg, Jan L., van Dijk, Boukje A.C., Oosting, Sjoukje F., Schuuring, Ed M.D., Langendijk, Johannes A., Halmos, Gyorgy B., Plaat, Boudewijn E.C.

“…•In 41% of the salvage neck dissections viable tumor was found.•Predictors of viable tumor: RT alone, increased lymph node size, and HPV negativity.•Consider…”
Get full text

Genome-wide methylation profiling reveals Zinc finger protein 516 (ZNF516) and FK-506-binding protein 6 (FKBP6) promoters frequently methylated in cervical neoplasia, associated with HPV status and ethnicity in a Chilean population by Brebi, Priscilla, Maldonado, Leonel, Noordhuis, Maartje G, Ili, Carmen, Leal, Pamela, Garcia, Patricia, Brait, Mariana, Ribas, Judit, Michailidi, Christina, Perez, Jimena, Soudry, Ethan, Tapia, Oscar, Guzman, Pablo, Muñoz, Sergio, Van Neste, Leander, Van Criekinge, Wim, Irizarry, Rafael, Sidransky, David, Roa, Juan C, Guerrero-Preston, Rafael

“…Cervical cancer is a major health concern among women in Latin America due to its high incidence and mortality. Therefore, the discovery of molecular markers…”
Get full text

Clinical and public health research using methylated DNA Immunoprecipitation (MeDIP): A comparison of commercially available kits to examine differential DNA methylation across the genome by Brebi-Mieville, Priscilla, Ili-Gangas, Carmen, Leal-Rojas, Pamela, Noordhuis, Maartje G., Soudry, Ethan, Perez, Jimena, Roa, Juan Carlos, Sidransky, David, Guerrero-Preston, Rafael

“…The methylated DNA immunoprecipitation method (MeDIP) is a genome-wide, high-resolution approach that detects DNA methylation with oligonucleotide tiling…”
Get full text

Correction: Association of Promoter Methylation of VGF and PGP9.5 with Ovarian Cancer Progression by Brait, Mariana, Maldonado, Leonel, Noordhuis, Maartje G., Begum, Shahnaz, Loyo, Myriam, Poeta, Maria Luana, Barbosa, Alvaro, Fazio, Vito M., Angioli, Roberto, Rabitti, Carla, Marchionni, Luigi, de Graeff, Pauline, J. van der Zee, Ate G., Wisman, G. Bea A., Sidransky, David, Hoque, Mohammad O.

Get full text

The epidermal growth factor receptor pathway in relation to pelvic lymph node metastasis and survival in early-stage cervical cancer by Eijsink, Jasper J.H., MD, Noordhuis, Maartje G, ten Hoor, Klaske A, Kok, Mirjam, Hollema, Harry, MD, PhD, de Bock, Geertruida H., PhD, Nijman, Hans W., MD, PhD, Schuuring, Ed, PhD, Wisman, G. Bea A., PhD, van der Zee, Ate G.J., MD, PhD

“…Summary The objective of this study is to correlate the expression of epidermal growth factor receptor (EGFR) components with clinical behavior of early-stage…”
Get full text