Search Results - "Noorani, Arshad"
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Familial Alzheimer mutations stabilize synaptotoxic γ-secretase-substrate complexes
Published in Cell reports (Cambridge) (27-02-2024)“…Mutations that cause familial Alzheimer’s disease (FAD) are found in amyloid precursor protein (APP) and presenilin, the catalytic component of γ-secretase,…”
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2
Presenilin Is Essential for ApoE Secretion, a Novel Role of Presenilin Involved in Alzheimer's Disease Pathogenesis
Published in The Journal of neuroscience (23-02-2022)“…Alzheimer's disease (AD) is a debilitating dementia characterized by progressive memory loss and aggregation of amyloid-β (Aβ) protein into amyloid plaques in…”
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Pretreatment of Albino Rats with Methanolic Fruit Extract of Randia Dumetorum ( L .) Protects against Alcohol Induced Liver Damage
Published in The Korean journal of physiology & pharmacology (01-04-2012)“…Alcohol abuse and its medical and social consequences are a major health problem in many areas of the world. The present study was conducted to evaluate the…”
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4
High temperature promotes amyloid β-protein production and γ-secretase complex formation via Hsp90
Published in The Journal of biological chemistry (25-12-2020)“…Alzheimer's disease (AD) is characterized by neuronal loss and accumulation of β-amyloid-protein (Aβ) in the brain parenchyma. Sleep impairment is associated…”
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Journal Article -
5
Pretreatment of Albino Rats with Methanolic Fruit Extract of Randia Dumetorum (L.) Protects against Alcohol Induced Liver Damage
Published in The Korean journal of physiology & pharmacology (01-01-2012)“…Alcohol abuse and its medical and social consequences are a major health problem in many areas of the world. The present study was conducted to evaluate the…”
Get full text
Journal Article -
6
High temperature promotes amyloid β-protein production and γ-secretase complex formation via Hsp90
Published in The Journal of biological chemistry (25-12-2020)“…Alzheimer's disease (AD) is characterized by neuronal loss and accumulation of β-amyloid-protein (Aβ) in the brain parenchyma. Sleep impairment is associated…”
Get full text
Journal Article