Search Results - "Noor Ahmad Shaik"

TagSNP approach for HLA risk allele genotyping of Saudi celiac disease patients: effectiveness and pitfalls by Baaqeel, Reham H, Banaganapalli, Babajan, Al Mahdi, Hadiah Bassam, Salama, Mohammed A, Alhussaini, Bakr H, Alaifan, Meshari A, Bin-Taleb, Yagoub, Shaik, Noor Ahmad, Al-Aama, Jumana Yousuf, Elango, Ramu, Saadah, Omar I

“…Celiac disease (CD) is a genetically complex autoimmune disease which is triggered by dietary gluten. Human leukocyte antigen (HLA) class II genes are known to…”
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Computational Molecular Phenotypic Analysis of PTPN22 (W620R), IL6R (D358A), and TYK2 (P1104A) Gene Mutations of Rheumatoid Arthritis by Shaik, Noor Ahmad, Banaganapalli, Babajan

“…Rheumatoid arthritis (RA) is a chronic autoimmune disorder of bone joints caused by the complex interplay between several factors like body physiology, the…”
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Tumor necrosis factor alpha –C850T polymorphism is significantly associated with endometriosis in Asian Indian women by Vijaya Lakshmi, Kodati, Ph.D, Shetty, Preetha, M.Sc, Vottam, Kiran, M.Sc, Govindhan, Sujatha, M.Sc, Ahmad, Shaik Noor, M.Sc, Hasan, Qurratulain, Ph.D

“…Objective To establish the association of tumor necrosis factor alpha (TNFA) promoter C850T polymorphism in Asian Indian women with endometriosis. Design Case…”
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Induced pluripotent stem cell modelling of HLHS underlines the contribution of dysfunctional NOTCH signalling to impaired cardiogenesis by Yang, Chunbo, Xu, Yaobo, Yu, Min, Lee, David, Alharti, Sameer, Hellen, Nicola, Ahmad Shaik, Noor, Banaganapalli, Babajan, Sheikh Ali Mohamoud, Hussein, Elango, Ramu, Przyborski, Stefan, Tenin, Gennadiy, Williams, Simon, O'Sullivan, John, Al-Radi, Osman O, Atta, Jameel, Harding, Sian E, Keavney, Bernard, Lako, Majlinda, Armstrong, Lyle

“…Hypoplastic left heart syndrome (HLHS) is among the most severe forms of congenital heart disease. Although the consensus view is that reduced flow through the…”
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Identification of miRNA–mRNA–TFs regulatory network and crucial pathways involved in asthma through advanced systems biology approaches by Shaik, Noor Ahmad, Nasser, Khalidah, Mohammed, Arif, Mujalli, Abdulrahman, Obaid, Ahmad A, El-Harouni, Ashraf A, Elango, Ramu, Banaganapalli, Babajan

“…Asthma is a life-threatening and chronic inflammatory lung disease that is posing a true global health challenge. The genetic basis of the disease is fairly…”
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Paget's disease: a review of the epidemiology, etiology, genetics, and treatment by Banaganapalli, Babajan, Fallatah, Ibrahim, Alsubhi, Fai, Shetty, Preetha Jayasheela, Awan, Zuhier, Elango, Ramu, Shaik, Noor Ahmad

“…Paget's disease of bone (PDB) is the second most prevalent metabolic bone disorder worldwide, with a prevalence rate of 1.5%-8.3%. It is characterized by…”
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Exploring the predictive power of jejunal microbiome composition in clinical and subclinical necrotic enteritis caused by Clostridium perfringens: insights from a broiler chicken model by Gautam, Hemlata, Ayalew, Lisanework E, Shaik, Noor Ahmad, Subhasinghe, Iresha, Popowich, Shelly, Chow-Lockerbie, Betty, Dixon, Alexa, Ahmed, Khawaja Ashfaque, Tikoo, Suresh K, Gomis, Susantha

“…Necrotic enteritis (NE) is a severe intestinal infection that affects both humans and poultry. It is caused by the bacterium Clostridium perfringens (CP), but…”
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Exploring celiac disease candidate pathways by global gene expression profiling and gene network cluster analysis by Banaganapalli, Babajan, Mansour, Haifa, Mohammed, Arif, Alharthi, Arwa Mastoor, Aljuaid, Nada Mohammed, Nasser, Khalidah Khalid, Ahmad, Aftab, Saadah, Omar I., Al-Aama, Jumana Yousuf, Elango, Ramu, Shaik, Noor Ahmad

“…Celiac disease (CeD) is a gastrointestinal autoimmune disorder, whose specific molecular basis is not yet fully interpreted. Therefore, in this study, we…”
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Identification of a de novo LRP1 mutation in a Saudi family with Tetralogy of Fallot by Alrayes, Nuha, Mallah, Bayan A, Issa, Noha M., Banaganapalli, Babajan, Ahmad Shaik, Noor, Nasser, Khalidah K., Alshehri, Bandar Ali, Bhuiyan, Zahurul A., Bdier, Amnah Y., Al-Aama, Jumana Y.

“…[Display omitted] •A novel heterozygous de novo mutation in LRP1 was identified.•LRP1 variant was predicted to be pathogenic, resulting in potential changes in…”
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SHH Signaling as a Key Player in Endometrial Cancer: Unveiling the Correlation with Good Prognosis, Low Proliferation, and Anti-Tumor Immune Milieu by Snijesh, V P, Krishnamurthy, Shivakumar, Bhardwaj, Vipul, Punya, K M, Niranjana Murthy, Ashitha S, Almutadares, Mahmoud, Habhab, Wisam Tahir, Nasser, Khalidah Khalid, Banaganapalli, Babajan, Shaik, Noor Ahmad, Albaqami, Walaa F

“…Endometrial Cancer (EC) is one of the most common gynecological malignancies. Despite its prevalence, molecular pathways, such as the Sonic Hedgehog (SHH)…”
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Anti-angiogenic effect of nano-formulated water soluble kaempferol and combretastatin in an in vivo chick chorioallantoic membrane model and HUVEC cells by Subbaraj, Gowtham Kumar, Masoodi, Tariq, Yasam, Santhosh Kumar, Chandrashekar, Kirubhanand, Kulanthaivel, Langeswaran, Shaik, Noor Ahmad, Hashem, Sheema, Alshabeeb Akil, Ammira S., Bhat, Ajaz A.

“…The present study evaluated the efficacy of nano-formulated water-soluble kaempferol and combretastatin alone and combined against the native kaempferol and…”
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Ramadan fasting in Saudi Arabia is associated with altered expression of CLOCK, DUSP and IL-1alpha genes, as well as changes in cardiometabolic risk factors by Ajabnoor, Ghada M A, Bahijri, Suhad, Shaik, Noor Ahmad, Borai, Anwar, Alamoudi, Aliaa A, Al-Aama, Jumana Y, Chrousos, George P

“…During the fasting month of Ramadan, practicing Saudis develop severe disturbances in sleeping and feeding patterns. Concomitantly, cortisol circadian rhythm…”
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Bioinformatics insights into the genes and pathways on severe COVID-19 pathology in patients with comorbidities by Mujalli, Abdulrahman, Alghamdi, Kawthar Saad, Nasser, Khalidah Khalid, Al-Rayes, Nuha, Banaganapalli, Babajan, Shaik, Noor Ahmad, Elango, Ramu

“…Coronavirus disease (COVID-19) infection is known for its severe clinical pathogenesis among individuals with pre-existing comorbidities. However, the…”
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A comparative mRNA- and miRNA transcriptomics reveals novel molecular signatures associated with metastatic prostate cancers by Shinawi, Thoraia, Nasser, Khalidah Khalid, Moradi, Fatima Amanullah, Mujalli, Abdulrahman, Albaqami, Walaa F., Almukadi, Haifa S., Elango, Ramu, Shaik, Noor Ahmad, Banaganapalli, Babajan

“…Background: Prostate cancer (PC) is a fatally aggressive urogenital cancer killing millions of men, globally. Thus, this study aims to identify key miRNAs,…”
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Computational approaches for discovering significant microRNAs, microRNA-mRNA regulatory pathways, and therapeutic protein targets in endometrial cancer by Ajabnoor, Ghada, Alsubhi, Fai, Shinawi, Thoraia, Habhab, Wisam, Albaqami, Walaa F, Alqahtani, Hussain S, Nasief, Hisham, Bondagji, Nabeel, Elango, Ramu, Shaik, Noor Ahmad, Banaganapalli, Babajan

“…Endometrial cancer (EC) is a urogenital cancer affecting millions of post-menopausal women, globally. This study aims to identify key miRNAs, target genes, and…”
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Identifying significant genes and functionally enriched pathways in familial hypercholesterolemia using integrated gene co-expression network analysis by Awan, Zuhier, Alrayes, Nuha, Khan, Zeenath, Almansouri, Majid, Ibrahim Hussain Bima, Abdulhadi, Almukadi, Haifa, Ibrahim Kutbi, Hussam, Jayasheela Shetty, Preetha, Ahmad Shaik, Noor, Banaganapalli, Babajan

“…Familial hypercholesterolemia (FH) is a monogenic lipid disorder which promotes atherosclerosis and cardiovascular diseases. Owing to the lack of sufficient…”
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In-silico analysis of inflammatory bowel disease (IBD) GWAS loci to novel connections by Mesbah-Uddin, Md, Elango, Ramu, Banaganapalli, Babajan, Shaik, Noor Ahmad, Al-Abbasi, Fahad A

“…Genome-wide association studies (GWASs) for many complex diseases, including inflammatory bowel disease (IBD), produced hundreds of disease-associated loci-the…”
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Protein structural insights into a rare PCSK9 gain-of-function variant (R496W) causing familial hypercholesterolemia in a Saudi family: whole exome sequencing and computational analysis by Shaik, Noor Ahmad, Al-Shehri, Najla, Athar, Mohammad, Awan, Ahmed, Khalili, Mariam, Al Mahadi, Hadiah Bassam, Hejazy, Gehan, Saadah, Omar I, Al-Harthi, Sameer Eida, Elango, Ramu, Banaganapalli, Babajan, Alefishat, Eman, Awan, Zuhier

“…Familial hypercholesterolemia (FH) is a globally underdiagnosed genetic condition associated with premature cardiovascular death. The genetic etiology data on…”
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Elevated levels of butyric acid in the jejunum of an animal model of broiler chickens: from early onset of Clostridium perfringens infection to clinical disease of necrotic enteritis by Gautam, Hemlata, Shaik, Noor Ahmad, Banaganapalli, Babajan, Popowich, Shelly, Subhasinghe, Iresha, Ayalew, Lisanework E, Mandal, Rupasri, Wishart, David S, Tikoo, Suresh, Gomis, Susantha

“…BackgroundNecrotic enteritis (NE) is an economically important disease of broiler chickens caused by Clostridium perfringens (CP). The pathogenesis, or disease…”
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Structural and Molecular Interaction Studies on Familial Hypercholesterolemia Causative PCSK9 Functional Domain Mutations Reveals Binding Affinity Alterations with LDLR by Awan, Zuhier Ahmed, Bahattab, Rawabi, Kutbi, Hussam Ibrahim, Noor, Ahmad Omar Jamal, Al-Nasser, Marzog S., Shaik, Noor Ahmad, Banaganapalli, Babajan

“…Familial hypercholesterolemia (FH) is a metabolic disease caused by the inherited pathogenic mutations in PCSK9 gene. This study has evaluated the potential of…”
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