Search Results - "Noor, Shahani"

Lifelong Impacts of Moderate Prenatal Alcohol Exposure on Neuroimmune Function by Noor, Shahani, Milligan, Erin D

“…alcohol exposure is emerging as a major risk factor for lifelong aberrant neuroimmune function. Fetal alcohol spectrum disorder encompasses a range of…”
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Ischemia/Reperfusion Induces Interferon-Stimulated Gene Expression in Microglia by McDonough, Ashley, Lee, Richard V, Noor, Shahani, Lee, Chungeun, Le, Thu, Iorga, Michael, Phillips, Jessica L H, Murphy, Sean, Möller, Thomas, Weinstein, Jonathan R

“…Innate immune signaling is important in the pathophysiology of ischemia/reperfusion (stroke)-induced injury and recovery. Several lines of evidence support a…”
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Ischemic preconditioning induces cortical microglial proliferation and a transcriptomic program of robust cell cycle activation by McDonough, Ashley, Noor, Shahani, Lee, Richard V., Dodge, Ryan, Strosnider, James S., Shen, Jasmine, Davidson, Stephanie, Möller, Thomas, Garden, Gwenn A., Weinstein, Jonathan R.

“…Ischemic preconditioning (IPC) is an experimental phenomenon in which a subthreshold ischemic insult applied to the brain reduces damage caused by a subsequent…”
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Moderate Prenatal Alcohol Exposure Increases Toll-like Receptor Activity in Umbilical Cord Blood at Birth: A Pilot Study by Maxwell, Jessie R, Noor, Shahani, Pavlik, Nathaniel, Rodriguez, Dominique E, Enriquez Marquez, Lidia, DiDomenico, Jared, Blossom, Sarah J, Bakhireva, Ludmila N

“…The prevalence of prenatal alcohol exposure (PAE) is increasing, with evidence suggesting that PAE is linked to an increased risk of infections. PAE is…”
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Role of C-C chemokine receptor type 7 and its ligands during neuroinflammation by Noor, Shahani, Wilson, Emma H

“…For decades, chemokines and their receptors have received a great deal of attention for their multiple roles in controlling leukocyte functions during…”
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SPARC coordinates extracellular matrix remodeling and efficient recruitment to and migration of antigen-specific T cells in the brain following infection by McGovern, Kathryn E., Nance, J. Philip, David, Clément N., Harrison, Reed E. S., Noor, Shahani, Worth, Danielle, Landrith, Tyler A., Obenaus, Andre, Carson, Monica J., Morikis, Dimitrios, Wilson, Emma H.

“…Central nervous system (CNS) injury and infection can result in profound tissue remodeling in the brain, the mechanism and purpose of which is poorly…”
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Biomass smoke inhalation promotes neuroinflammatory and metabolomic temporal changes in the hippocampus of female mice by Scieszka, David, Jin, Yan, Noor, Shahani, Barr, Ed, Garcia, Marcus, Begay, Jessica, Herbert, Guy, Hunter, Russell P, Bhaskar, Kiran, Kumar, Rahul, Gullapalli, Rama, Bolt, Alicia, McCormick, Mark A, Bleske, Barry, Gu, Haiwei, Campen, Matthew J

“…Smoke from wildland fires has been shown to produce neuroinflammation in preclinical models, characterized by neural infiltrations of neutrophils and…”
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Prenatal alcohol exposure potentiates chronic neuropathic pain, spinal glial and immune cell activation and alters sciatic nerve and DRG cytokine levels by Noor, Shahani, Sanchez, Joshua J, Vanderwall, Arden G, Sun, Melody S, Maxwell, Jessie R, Davies, Suzy, Jantzie, Lauren L, Petersen, Timothy R, Savage, Daniel D, Milligan, Erin D

“…Highlights • Moderate prenatal alcohol exposure (PAE) potentiates chronic neuropathic pain. • PAE induces exaggerated spinal glial activation following…”
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Prenatal alcohol exposure is a risk factor for adult neuropathic pain via aberrant neuroimmune function by Sanchez, Joshua J, Noor, Shahani, Davies, Suzy, Savage, Daniel, Milligan, Erin D

“…Clinical studies show that prenatal alcohol exposure (PAE) results in effects that persist into adulthood. Experimental animal models of moderate PAE…”
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CXCR2 Blockade Mitigates Neural Cell Injury Following Preclinical Chorioamnionitis by Yellowhair, Tracylyn R, Newville, Jessie C, Noor, Shahani, Maxwell, Jessie R, Milligan, Erin D, Robinson, Shenandoah, Jantzie, Lauren L

“…Minimizing central nervous system (CNS) injury from preterm birth depends upon identification of the critical pathways that underlie essential…”
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Prenatal alcohol exposure alters mRNA expression for stress peptides, glucocorticoid receptor function and immune factors in acutely stressed neonatal brain by Ruffaner-Hanson, Chaselyn D, Fernandez-Oropeza, Annette K, Sun, Melody S, Caldwell, Kevin K, Allan, Andrea M, Savage, Daniel D, Valenzuela, C Fernando, Noor, Shahani, Milligan, Erin D

“…The amygdala, hippocampus and hypothalamus are critical stress regulatory areas that undergo functional maturation for stress responding initially established…”
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Chitinase dependent control of protozoan cyst burden in the brain by Nance, J Philip, Vannella, Kevin M, Worth, Danielle, David, Clément, Carter, David, Noor, Shahani, Hubeau, Cedric, Fitz, Lori, Lane, Thomas E, Wynn, Thomas A, Wilson, Emma H

“…Chronic infections represent a continuous battle between the host's immune system and pathogen replication. Many protozoan parasites have evolved a cyst…”
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Prenatal alcohol exposure dysregulates spinal and circulating immune cell circular RNA expression in adult female rats with chronic sciatic neuropathy by Noor, Shahani, Pritha, Ariana N, Pasmay, Andrea A, Sanchez, Jacob E, Sanchez, Joshua J, Fernandez-Oropeza, Annette K, Sun, Melody S, Dell'Orco, Michela, Davies, Suzy, Savage, Daniel D, Mellios, Nikolaos, Milligan, Erin D

“…Alcohol consumption during pregnancy is associated with Fetal Alcohol Spectrum Disorders (FASD) that results in a continuum of central nervous system (CNS)…”
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CCR7-Dependent Immunity during Acute Toxoplasma gondii Infection by Noor, Shahani, Habashy, Andrew S, Nance, J. Philip, Clark, Robin T, Nemati, Kiav, Carson, Monica J, Wilson, Emma H

“…The chemokine receptor CCR7 is a well-established homing receptor for dendritic cells and T cells. Interactions with its ligands, CCL19 and CCL21, facilitate…”
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Targeting the β2-integrin LFA-1, reduces adverse neuroimmune actions in neuropathic susceptibility caused by prenatal alcohol exposure by Sanchez, Joshua J, Sanchez, Jacob E, Noor, Shahani, Ruffaner-Hanson, Chaselyn D, Davies, Suzy, Wagner, Carston R, Jantzie, Lauren L, Mellios, Nikolaos, Savage, Daniel D, Milligan, Erin D

“…Recently, moderate prenatal alcohol exposure (PAE) was shown to be a risk factor for peripheral neuropathy following minor nerve injury. This effect coincides…”
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Profiling CD8+ CD103+ T cells in the Toxoplasma gondii infected brain by Landrith, Tyler, Noor, Shahani, Wilson, Emma H

“…Abstract Toxoplasma gondii is an obligate intracellular protozoan parasite. The parasite evades clearance by the immune system and instead persists in an…”
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Maternal alcohol drinking patterns predict offspring neurobehavioral outcomes by Myrick, Abbey, Jimenez, Diane, Jacquez, Belkis, Sun, Melody S., Noor, Shahani, Milligan, Erin D., Valenzuela, C. Fernando, Linsenbardt, David N.

“…The timing, rate, and quantity of gestational alcohol consumption, collectively referred to here as Maternal Drinking Patterns (MDPs), are of known importance…”
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CCR7+ dendritic cells are sufficient to recover a defective population of KLRG1+ T cells in the brain of chronically infected CCR7-/- mice (MPF7P.716) by Landrith, Tyler, Noor, Shahani, Wilson, Emma

“…Abstract Toxoplasma gondii is a protozoan parasite that establishes a chronic infection in the brain. CCR7-/- mice are susceptible to challenge with normally…”
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Aging Exacerbates Neuroinflammatory Outcomes Induced by Acute Ozone Exposure by Tyler, Christina R, Noor, Shahani, Young, Tamara L, Rivero, Valeria, Sanchez, Bethany, Lucas, Selita, Caldwell, Kevin K, Milligan, Erin D, Campen, Matthew J

“…Abstract The role of environmental stressors, particularly exposure to air pollution, in the development of neurodegenerative disease remains underappreciated…”
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The maternal-placental-fetal interface: Adaptations of the HPA axis and immune mediators following maternal stress and prenatal alcohol exposure by Ruffaner-Hanson, Chaselyn, Noor, Shahani, Sun, Melody S., Solomon, Elizabeth, Marquez, Lidia Enriquez, Rodriguez, Dominique E., Allan, Andrea M., Caldwell, Kevin K., Bakhireva, Ludmila N., Milligan, Erin D.

“…This review addresses underlying physiological, cellular, and molecular factors that alter the developing fetal brain stress circuits and responses of the…”
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