Search Results - "Noonan, Emily J"
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MicroRNA-373 Induces Expression of Genes with Complementary Promoter Sequences
Published in Proceedings of the National Academy of Sciences - PNAS (05-02-2008)“…Recent studies have shown that microRNA (miRNA) regulates gene expression by repressing translation or directing sequence-specific degradation of complementary…”
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Non-coding RNAs turn up the heat: An emerging layer of novel regulators in the mammalian heat shock response
Published in Cell stress & chaperones (01-03-2014)“…The field of non-coding RNA (ncRNA) has expanded over the last decade following the discoveries of several new classes of regulatory ncRNA. A growing amount of…”
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Perspectives of Transgender and Nonbinary Health Care Providers on Gender Minority Patient Simulation
Published in Academic medicine (01-11-2022)Get full text
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Prognostic value and function of KLF4 in prostate cancer: RNAa and vector-mediated overexpression identify KLF4 as an inhibitor of tumor cell growth and migration
Published in Cancer research (Chicago, Ill.) (15-12-2010)“…KLF4/GLKF4 is a transcription factor that can have divergent functions in different malignancies. The role of KLF4 in prostate cancer etiology remains unclear…”
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Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function
Published in Molecular cancer therapeutics (01-10-2008)“…Androgen receptor (AR) is a ligand-activated transcription factor belonging to the steroid hormone receptor family and is very important for the development…”
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Defining features and exploring chemical modifications to manipulate RNAa activity
Published in Current pharmaceutical biotechnology (01-08-2010)“…RNA interference (RNAi) is an evolutionary conserved mechanism by which small double-stranded RNA (dsRNA)--termed small interfering RNA (siRNA)--inhibit…”
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Gender-Affirming Care With Transgender and Genderqueer Patients: A Standardized Patient Case
Published in MedEdPORTAL (2022)“…Transgender and gender-diverse (TGD) patients experience health disparities and bias in health care settings. To improve care for TGD patients, medical…”
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miR-449a causes Rb-dependent cell cycle arrest and senescence in prostate cancer cells
Published in Oncotarget (30-09-2010)Get full text
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Formulation of Small Activating RNA Into Lipidoid Nanoparticles Inhibits Xenograft Prostate Tumor Growth by Inducing p21 Expression
Published in Molecular therapy. Nucleic acids (01-03-2012)“…Application of RNA interference (RNAi) in the clinic has improved with the development of novel delivery reagents (e.g., lipidoids). Although RNAi promises a…”
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Engaging Premedical Students in Medical Education Research: Benefits of Clinical Skills Observation Studies
Published in Academic medicine (01-11-2023)“…Observations requiring evaluation and critical thinking can be powerful learning experiences. Video-recorded standardized patient encounters are underutilized…”
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Gender Diverse Representation in Patient Simulation: A Scoping Review
Published in Academic medicine (01-11-2022)“…PURPOSEDespite recent advocacy for transgender and nonbinary (TGNB) health competencies in medical education, there is little guidance on how to represent…”
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Physiatry and the needs of LGBTQIA+ patients
Published in PM & R (01-06-2022)Get full text
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Barriers to USMLE Step-1 accommodations: Students with Type 1 Diabetes
Published in PloS one (18-06-2024)“…Students who earn their medical doctorate (MD) in the U.S. must pass the United States Medical Licensing Exam (USMLE) Step-1. The application process for…”
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Surface Expression of Hsp70B' in Response to Proteasome Inhibition in Human Colon Cells
Published in Cell stress & chaperones (01-03-2008)“…Hsp70B' was expressed on the surface of HT-29 and CRL-1809 but not SW-480 human colon cell lines in response to proteasome inhibition as detected using flow…”
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Cell number-dependent regulation of Hsp70B′ expression: Evidence of an extracellular regulator
Published in Journal of cellular physiology (01-01-2007)“…Hsp70B′ is a unique member of the human Hsp70 family of chaperones about which information is scarce. Unlike the major inducible Hsp72 protein, Hsp70B′ is…”
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Engaging the Transgender Community to Improve Medical Education and Prioritize Healthcare Initiatives
Published in Teaching and learning in medicine (03-04-2018)“…Phenomenon: Transgender patients experience discrimination, limited access to care, and inadequate provider knowledge in healthcare settings. Medical education…”
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LGBTQ+ Microaggressions in Health Care: Piloting an Observation Framework in a Standardized Patient Assessment
Published in Journal of homosexuality (28-01-2024)“…Microaggressions are subtle derogatory behaviors that unintentionally communicate hostility toward marginalized social groups. This article describes the…”
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Oxidative stress‐responsive microRNA‐320 regulates glycolysis in diverse biological systems
Published in The FASEB journal (01-11-2012)“…Glycolysis is the initial step of glucose catabolism and is up‐regulated in cancer cells (the Warburg Effect). Such shifts toward a glycolytic phenotype have…”
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Epistemic Peerhood as a Model To Improve Gender-Affirming Care in Medical Education
Published in Teaching and learning in medicine (01-01-2024)“…Issue : Inadequate training around gender-affirming care is a critical gap in health care and medical education that causes disparities and leads to injury for…”
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Gender Minorities in Simulation: A Mixed Methods Study of Medical School Standardized Patient Programs in the United States and Canada
Published in Simulation in healthcare : journal of the Society for Medical Simulation (01-12-2021)“…PURPOSEA providerʼs ability to translate knowledge about transgender health to affirming patient care is key to addressing disparities. However, standardized…”
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