Search Results - "Noonan, Alex M"

Paraspinal muscle pathophysiology associated with low back pain and spine degenerative disorders by Noonan, Alex M., Brown, Stephen H. M.

“…Low back pain disorders affect more than 80% of adults in their lifetime and are the leading cause of global disability. The muscles attaching to the spine…”
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Glycerol induced paraspinal muscle degeneration leads to hyper-kyphotic spinal deformity in wild-type mice by Noonan, Alex M., Buliung, Emily, Briar, K. Josh, Quinonez, Diana, Séguin, Cheryle A., Brown, Stephen H. M.

“…Degenerative spinal disorders, including kyphotic deformity, are associated with a range of degenerative characteristics of the paraspinal musculature. It has…”
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Training Induced Changes to Skeletal Muscle Passive Properties Are Evident in Both Single Fibers and Fiber Bundles in the Rat Hindlimb by Noonan, Alex M., Mashouri, Parastoo, Chen, Jackey, Power, Geoffrey A., Brown, Stephen H. M.

“…Introduction: The passive mechanical behavior of skeletal muscle represents both important and generally underappreciated biomechanical properties with little…”
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Modifiability of residual force depression in single muscle fibers following uphill and downhill training in rats by Mashouri, Parastoo, Chen, Jackey, Noonan, Alex M., Brown, Stephen H. M., Power, Geoffrey A.

“…Following active muscle shortening, steady‐state isometric force is less than a purely isometric contraction at the same muscle length and level of activation;…”
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Paraspinal Muscle Contractile Function is Impaired in the ENT1-deficient Mouse Model of Progressive Spine Pathology by Noonan, Alex M., Séguin, Cheryle A., Brown, Stephen H. M.

“…Basic science study of the relationship between spine pathology and the contractile ability of the surrounding muscles. To investigate single muscle fibre…”
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Comparing contractile properties within an integrated group of muscles: The abdominal wall by Siebenaller, Aliza R., Noonan, Alex M., Brown, Stephen H.M.

“…The abdominal wall (external oblique (EO), internal oblique (IO), rectus abdominis (RA), and transverse abdominis (TrA)) is a functionally and anatomically…”
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Paraspinal muscle fibre structural and contractile characteristics demonstrate distinct irregularities in patients with spinal degeneration and deformity by Noonan, Alex M, Malakoutian, Masoud, Dehghan-Hamani, Iraj, Lewis, Stephen, Street, John, Oxland, Thomas R, Brown, Stephen H M

“…Paraspinal and spinopelvic muscular dysfunction are hypothesized to be a causative factor for spinal degeneration and deformity; however, our fundamental…”
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Investigating the active contractile function of the rat paraspinal muscles reveals unique cross-bridge kinetics in the multifidus by Noonan, Alex M., Oxland, Thomas R., Brown, Stephen H. M.

“…Purpose Various aspects of paraspinal muscle anatomy, biology, and histology have been studied; however, information on paraspinal muscle contractile function…”
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Rate of force development is Ca2+-dependent and influenced by Ca2+-sensitivity in human single muscle fibres from older adults by Mazara, Nicole, Zwambag, Derek P., Noonan, Alex M., Weersink, Erin, Brown, Stephen H.M., Power, Geoffrey A.

“…Natural adult aging is associated with declines in skeletal muscle performance, including impaired Ca2+ sensitivity and a slowing of rapid force production…”
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The influence of training-induced sarcomerogenesis on the history dependence of force by Chen, Jackey, Mashouri, Parastoo, Fontyn, Stephanie, Valvano, Mikella, Elliott-Mohamed, Shakeap, Noonan, Alex M, Brown, Stephen H M, Power, Geoffrey A

“…The increase or decrease in isometric force following active muscle lengthening or shortening, relative to a reference isometric contraction at the same muscle…”
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Age-related changes in human single muscle fibre passive elastic properties are sarcomere length dependent by Noonan, Alex M., Mazara, Nicole, Zwambag, Derek P., Weersink, Erin, Power, Geoffrey A., Brown, Stephen H.M.

“…Studies have revealed an age-related decrease in the ability to produce force as well as an increase in the contractile stiffness and passive stress of single…”
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Dysfunctional paraspinal muscles in adult spinal deformity patients lead to increased spinal loading by Malakoutian, Masoud, Noonan, Alex M., Dehghan-Hamani, Iraj, Yamamoto, Shun, Fels, Sidney, Wilson, David, Doroudi, Majid, Schutz, Peter, Lewis, Stephen, Ailon, Tamir, Street, John, Brown, Stephen H. M., Oxland, Thomas R.

“…Purpose Decreased spinal extensor muscle strength in adult spinal deformity (ASD) patients is well-known but poorly understood; thus, this study aimed to…”
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The relationship between single muscle fibre and voluntary rate of force development in young and old males by Dalton, Benjamin E., Mazara, Nicole, Debenham, Mathew I. B., Zwambag, Derek P., Noonan, Alex M., Weersink, Erin, Brown, Stephen H. M., Power, Geoffrey A.

“…Purpose It is suggested that the early phase (< 50 ms) of force development during a muscle contraction is associated with intrinsic contractile properties,…”
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Fiber Type and Size as Sources of Variation in Human Single Muscle Fiber Passive Elasticity by Noonan, Alex M, Zwambag, Derek P, Mazara, Nicole, Weersink, Erin, Power, Geoffrey A, Brown, Stephen H M

“…Studies on single muscle fiber passive material properties often report relatively large variation in elastic modulus (or normalized stiffness), and it is not…”
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An air-spring standing platform does not increase overall movement or metabolic cost during simulated work tasks by Noonan, Alex M., Solomon, Michael, Gregory, Diane E., Burr, Jamie F., Brown, Stephen H.M.

“…Due to the increased popularity of standing-based occupational work stations there is a growing need to understand the impact of ergonomic aids such as…”
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Paraspinal Muscle Contractile Function is Impaired in the ENT1 Deficient Mouse Model of Progressive Spine Pathology by Noonan, Alex M., Séguin, Cheryle A., Brown, Stephen H. M.

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Rate of force development is Ca 2+ -dependent and influenced by Ca 2+ -sensitivity in human single muscle fibres from older adults by Mazara, Nicole, Zwambag, Derek P, Noonan, Alex M, Weersink, Erin, Brown, Stephen H M, Power, Geoffrey A

“…Natural adult aging is associated with declines in skeletal muscle performance, including impaired Ca sensitivity and a slowing of rapid force production (rate…”
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The influence of training-induced sarcomerogenesis on the history dependence of force by Chen, Jackey, Mashouri, Parastoo, Fontyn, Stephanie, Valvano, Mikella, Elliott-Mohamed, Shakeap, Noonan, Alex M, Brown, Stephen H M, Power, Geoffrey A

“…The increase or decrease in isometric force following active muscle lengthening or shortening, relative to a reference isometric contraction at the same muscle…”
Get full text