Search Results - "Noon, Angela T"

53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair by Löbrich, Markus, Jeggo, Penelope A, Noon, Angela T, Rief, Nicole, Goodarzi, Aaron A, Shibata, Atsushi, Stewart, Grant S

“…DNA double-strand breaks (DSBs) trigger ATM (ataxia telangiectasia mutated) signalling and elicit genomic rearrangements and chromosomal fragmentation if…”
Get full text

The impact of heterochromatin on DSB repair by Goodarzi, Aaron A, Noon, Angela T, Jeggo, Penny A

“…DNA NHEJ (non-homologous end-joining) is the major DNA DSB (double-strand break) repair pathway in mammalian cells. Although NHEJ-defective cell lines show…”
Get more information

Organization of Interphase Microtubules in Fission Yeast Analyzed by Electron Tomography by Höög, Johanna L., Schwartz, Cindi, Noon, Angela T., O'Toole, Eileen T., Mastronarde, David N., McIntosh, J. Richard, Antony, Claude

“…Polarized cells, such as neuronal, epithelial, and fungal cells, all display a specialized organization of their microtubules (MTs). The interphase MT…”
Get full text

ATM Signaling Facilitates Repair of DNA Double-Strand Breaks Associated with Heterochromatin by Goodarzi, Aaron A., Noon, Angela T., Deckbar, Dorothee, Ziv, Yael, Shiloh, Yosef, Löbrich, Markus, Jeggo, Penny A.

“…Ataxia Telangiectasia Mutated (ATM) signaling is essential for the repair of a subset of DNA double-strand breaks (DSBs); however, its precise role is unclear…”
Get full text

Analysis of Human Syndromes with Disordered Chromatin Reveals the Impact of Heterochromatin on the Efficacy of ATM-Dependent G2/M Checkpoint Arrest by Brunton, Holly, Goodarzi, Aaron A., Noon, Angela T., Shrikhande, Amruta, Hansen, R. Scott, Jeggo, Penny A., Shibata, Atsushi

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Role of ATM and the Damage Response Mediator Proteins 53BP1 and MDC1 in the Maintenance of G2/M Checkpoint Arrest by Shibata, Atsushi, Barton, Olivia, Noon, Angela T., Dahm, Kirsten, Deckbar, Dorothee, Goodarzi, Aaron A., Löbrich, Markus, Jeggo, Penny A.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Role of ATM and the damage response mediator proteins 53BP1 and MDC1 in the maintenance of G(2)/M checkpoint arrest by Shibata, Atsushi, Barton, Olivia, Noon, Angela T, Dahm, Kirsten, Deckbar, Dorothee, Goodarzi, Aaron A, Löbrich, Markus, Jeggo, Penny A

“…ATM-dependent initiation of the radiation-induced G(2)/M checkpoint arrest is well established. Recent results have shown that the majority of DNA…”
Get full text

53BP1-mediated DNA double strand break repair: Insert bad pun here by Noon, Angela T., Goodarzi, Aaron A.

“…53BP1 is an established player in the cellular response to DNA damage and is a canonical component of ionizing-radiation induced foci – that cadre of proteins…”
Get full text

Heterochromatic DNA Double Strand Break Repair by GOODARZI, Aaron A., NOON, Angela T., JEGGO, Penny A.

“…Eukaryotic chromatin is segregated into highly condensed heterochromatin and comparably relaxed euchromatin. Although heterochromatic gene expression is either…”
Get full text

The Maintenance of ATM Dependent G2/M Checkpoint Arrest Following Exposure to Ionizing Radiation by SHIBATA, Atsushi, BARTON, Olivia, NOON, Angela T., DAHM, Kirsten, DECKBAR, Dorothee, GOODARZI, Aaron A., LÖBRICH, Markus, JEGGO, Penny A.

“…The G2/M checkpoint is important in preventing cells with unrepaired DNA double strand breaks (DSBs) entering mitosis, an event which is likely to result in…”
Get full text

Analysis of Human Syndromes with Disordered Chromatin Reveals the Impact of Heterochromatin on the Efficacy of ATM-Dependent G 2 /M Checkpoint Arrest by Brunton, Holly, Goodarzi, Aaron A., Noon, Angela T., Shrikhande, Amruta, Hansen, R. Scott, Jeggo, Penny A., Shibata, Atsushi

Get full text

Investigating the role of 53bp1 in dna double strand break repair and checkpoint signalling by Noon, Angela T

“…DNA double strand breaks arise endogenously in the cell as a result of routine activities such as metabolism and also as a result of exposure to exogenous…”
Get full text

Role of ATM and the Damage Response Mediator Proteins 53BP1 and MDC1 in the Maintenance of G 2 /M Checkpoint Arrest by Shibata, Atsushi, Barton, Olivia, Noon, Angela T., Dahm, Kirsten, Deckbar, Dorothee, Goodarzi, Aaron A., Löbrich, Markus, Jeggo, Penny A.

Get full text