Search Results - "Nooijen, Irene"

P172 - I-screen: An ex vivo human microbiome platform to study microbiome induced reverse metabolism of metabolites back to parent by van de Steeg, Evita, Schuren, Frank, Nooijen, Irene, Erpelinck, Steven, Obach, R. Scott, Vaes, Wouter

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A8 - Apical and basolateral flow rate influence intestinal absorption in fresh intestinal tissue inside a novel intestine on a chip model by Amirabadi, Hossein Eslami, Boogaard, Joline, Wierenga, Esmée, Donkers, Tim, Grölers-Mulderij, Mariska, Stevens, Lianne, Usta, Birol, Pieters, Lisanne, Ingenhut, Bastiaan, Nooijen, Irene, Masereeuw, Rosalinde, van de Steeg, Evita

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Human ex vivo model to study intestinal processes and microbiome induced metabolism by Stevens, Lianne, Nooijen, Irene, Erpelinck, Steven, Obach, Ronald Scott, Walker, Gregory, Schuren, Frank, Speulman, Angelique, Grollers, Mariska, Vaes, Wouter, van de Steeg, Evita

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I-screen: In vitro platform to study human gut microbiota induced drug metabolism and molecular transformations by Erpelinck, Steven, Schuren, Frank H.J., Nooijen, Irene H.G., Scott Obach, R., Walker, Gregory S., van de Steeg, Evita, Vaes, Wouter H.

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Ex vivo whole liver perfusion model for prediction of drug-drug interactions and biliary excretion of rosuvastatin by van de Steeg, Evita, van Koppen, Arianne, Speulman, Angelique E.A.M., van der Plaats, Arjan, Offringa, Emma, Stevens, Lianne J., Nooijen, Irene H.G., Erpelinck, Steven L.A., Vaes, Wouter H.J.

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Intestinal explant barrier chip: long-term intestinal absorption screening in a novel microphysiological system using tissue explants by Eslami Amirabadi, Hossein, Donkers, Joanne M, Wierenga, Esmée, Ingenhut, Bastiaan, Pieters, Lisanne, Stevens, Lianne, Donkers, Tim, Westerhout, Joost, Masereeuw, Rosalinde, Bobeldijk-Pastorova, Ivana, Nooijen, Irene, van de Steeg, Evita

“…The majority of intestinal screening models use cell lines that do not reflect the complexity of the human intestinal tract and hence often fail to accurately…”
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Digestion and Transport across the Intestinal Epithelium Affects the Allergenicity of Ara h 1 and 3 but Not of Ara h 2 and 6 by Smits, Mark, Nooijen, Irene, Redegeld, Frank, Jong, Aard, Le, Thuy‐My, Knulst, André, Houben, Geert, Verhoeckx, Kitty

“…Scope No accepted and validated methods are currently available which can accurately predict protein allergenicity. In this study, the role of digestion and…”
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Quantification of azacitidine incorporation into human DNA/RNA by accelerator mass spectrometry as direct measure of target engagement by Wang, Xiaomin, Vaes, Wouter H.J., van Duijn, Esther, Nooijen, Irene, Tong, Zeen, de Menezes, Daniel Lopes, Maxwell, Stephen E.

“…•We quantified azacitidine (Aza) incorporation into DNA and RNA from BM and PBMCs.•The assay quantified one Aza molecule in DNA with ∼2 × 107 nucleotides from…”
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