Search Results - "Nonomiya, Yuma"

Novel pharmacological effects of poly (ADP-ribose) polymerase inhibitor rucaparib on the lactate dehydrogenase pathway by Nonomiya, Yuma, Noguchi, Kohji, Katayama, Kazuhiro, Sugimoto, Yoshikazu

“…Poly (ADP-ribose) polymerases (PARPs) are involved in various cellular events, including DNA repair. PARP inhibitors including olaparib and rucaparib, have…”
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Analysis of Adverse Events Associated with Trastuzumab Deruxtecan in Patients with Gastric and Breast Cancer: A Retrospective Study by Nonomiya, Yuma, Nakayama, Izuma, Kobayashi, Kazuo, Amakawa, Yoshihiro, Shibata, Naoki, Soejima, Azusa, Kawakami, Kazuyoshi, Shimizu, Hisanori, Takahari, Daisuke, Kawai, Saori, Hara, Fumikata, Takano, Toshimi, Yamaguchi, Kensei, Yamaguchi, Masakazu

“…Trastuzumab deruxtecan (T-DXd) has displayed demonstrable efficacy and manageable toxicity in previously treated patients with advanced gastric and breast…”
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Effect of AKT3 expression on MYC‐ and caspase‐8‐dependent apoptosis caused by polo‐like kinase inhibitors in HCT 116 cells by Nonomiya, Yuma, Noguchi, Kohji, Tanaka, Noritaka, Kasagaki, Takahiro, Katayama, Kazuhiro, Sugimoto, Yoshikazu

“…Polo‐like kinase (PLK) is a cell‐cycle regulator that is overexpressed in several cancer cell types. Polo‐like kinase is considered a novel target for cancer…”
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Functional Effects of AKT3 on Aurora Kinase Inhibitor-induced Aneuploidy by Noguchi, Kohji, Hongama, Keita, Hariki, Shiori, Nonomiya, Yuma, Katayama, Kazuhiro, Sugimoto, Yoshikazu

“…The suppression of mitotic Aurora kinases (AURKs) by AURK inhibitors frequently causes cytokinetic failure, leading to polyploidy or aneuploidy, indicating the…”
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Regorafenib-Induced Hand-Foot Skin Reaction Is More Severe on the Feet Than on the Hands by Nonomiya, Yuma, Yokokawa, Takashi, Kawakami, Kazuyoshi, Kobayashi, Kazuo, Aoyama, Takeshi, Takiguchi, Tomomi, Sugisaki, Takahito, Suzuki, Kenichi, Suenaga, Mitsukuni, Wakatsuki, Takeru, Yamaguchi, Kensei, Sugimoto, Yoshikazu, Hama, Toshihiro

“…Regorafenib is a multikinase inhibitor for the treatment of metastatic colorectal cancer. Regorafenib-induced hand-foot skin reaction (HFSR) is a common side…”
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Effect of AKT 3 expression on MYC ‐ and caspase‐8‐dependent apoptosis caused by polo‐like kinase inhibitors in HCT 116 cells by Nonomiya, Yuma, Noguchi, Kohji, Tanaka, Noritaka, Kasagaki, Takahiro, Katayama, Kazuhiro, Sugimoto, Yoshikazu

“…Polo‐like kinase ( PLK ) is a cell‐cycle regulator that is overexpressed in several cancer cell types. Polo‐like kinase is considered a novel target for cancer…”
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