Search Results - "Nonnecke, Brian J."

Vitamin D signaling in the bovine immune system: a model for understanding human vitamin D requirements by Nelson, Corwin D, Reinhardt, Timothy A, Lippolis, John D, Sacco, Randy E, Nonnecke, Brian J

“…The endocrine physiology of vitamin D in cattle has been rigorously investigated and has yielded information on vitamin D requirements, endocrine function in…”
Get full text

Regulation of Mycobacterium-specific mononuclear cell responses by 25-hydroxyvitamin D3 by Nelson, Corwin D, Nonnecke, Brian J, Reinhardt, Timothy A, Waters, W. Ray, Beitz, Donald C, Lippolis, John D

“…The active vitamin D metabolite, 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)), has been shown to be an important regulator of innate and adaptive immune…”
Get full text

Bovine milk exosome proteome by Reinhardt, Timothy A., Lippolis, John D., Nonnecke, Brian J., Sacco, Randy E.

“…Exosomes are 40–100nm membrane vesicles of endocytic origin, secreted by cells and are found in biological fluids including milk. These exosomes are…”
Get full text

Neonatal calf infection with respiratory syncytial virus: drawing parallels to the disease in human infants by Sacco, Randy E, McGill, Jodi L, Palmer, Mitchell V, Lippolis, John D, Reinhardt, Timothy A, Nonnecke, Brian J

“…Respiratory syncytial virus (RSV) is the most common viral cause of childhood acute lower respiratory tract infections. It is estimated that RSV infections…”
Get full text

Differential expression of cytokines in response to respiratory syncytial virus infection of calves with high or low circulating 25-hydroxyvitamin D3 by Sacco, Randy E, Nonnecke, Brian J, Palmer, Mitchell V, Waters, W. Ray, Lippolis, John D, Reinhardt, Timothy A

“…Deficiency of serum levels of 25-hydroxyvitamin D3 has been related to increased risk of lower respiratory tract infections in children. Respiratory syncytial…”
Get full text

Effects of mastectomy on composition of peripheral blood mononuclear cell populations in periparturient dairy cows by Kimura, Kayoko, Goff, Jesse P, Kehrli, Jr, Marcus E, Harp, James A, Nonnecke, Brian J

“…There is an increased incidence of infectious disease in periparturient dairy cows. During the periparturient period there is a decline in T-lymphocyte cell…”
Get more information

Signal regulatory protein alpha (SIRPalpha) cells in the adaptive response to ESAT-6/CFP-10 protein of tuberculous mycobacteria by Waters, W Ray, Palmer, Mitchell V, Nonnecke, Brian J, Thacker, Tyler C, Estes, D Mark, Larsen, Michelle H, Jacobs, Jr, William R, Andersen, Peter, McNair, James, Minion, F C, Lyashchenko, Konstantin P, Hewinson, R Glyn, Vordermeier, H Martin, Sacco, Randy E

“…Early secretory antigenic target-6 (ESAT-6) and culture filtrate protein-10 (CFP-10) are co-secreted proteins of Mycobacterium tuberculosis complex…”
Get full text

Differential chemokine and cytokine production by neonatal bovine gamma delta T-cell subsets in response to viral toll-like receptor agonists and in vivo respiratory syncytial virus infection by McGill, Jodi L, Nonnecke, Brian J, Lippolis, John D, Reinhardt, Timothy A, Sacco, Randy E

“…gamma delta T cells respond to stimulation via toll-like receptors (TLR). Bovine gamma delta T cells express TLR3 and TLR7, receptors that are key for the…”
Get full text

Differential chemokine and cytokine production by neonatal bovine γδ T‐cell subsets in response to viral toll‐like receptor agonists and in vivo respiratory syncytial virus infection by McGill, Jodi L., Nonnecke, Brian J., Lippolis, John D., Reinhardt, Timothy A., Sacco, Randy E.

“…Summary γδ T cells respond to stimulation via toll‐like receptors (TLR). Bovine γδ T cells express TLR3 and TLR7, receptors that are key for the recognition of…”
Get full text

Proteomic analysis reveals protein expression differences in Escherichia coli strains associated with persistent versus transient mastitis by Lippolis, John D., Brunelle, Brian W., Reinhardt, Timothy A., Sacco, Randy E., Nonnecke, Brian J., Dogan, Belgin, Simpson, Kenneth, Schukken, Ynte H.

“…Escherichia coli is a leading cause of bacterial mastitis in dairy cattle. Typically this infection is transient in nature, causing an infection that lasts…”
Get full text

Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis by Reinhardt, Timothy A., Sacco, Randy E., Nonnecke, Brian J., Lippolis, John D.

“…Milk protein expression in healthy cows and cows with mastitis will provide information important for the dairy food industry and immune function in the…”
Get full text

Efficacy and immunogenicity of Mycobacterium bovis Δ RD1 against aerosol M. bovis infection in neonatal calves by Waters, W. Ray, Palmer, Mitchell V, Nonnecke, Brian J, Thacker, Tyler C, Scherer, Charles F. Capinos, Estes, D. Mark, Hewinson, R. Glyn, Vordermeier, H. Martin, Barnes, S. Whitney, Federe, Glenn C, Walker, John R, Glynne, Richard J, Hsu, Tsungda, Weinrick, Brian, Biermann, Karolin, Larsen, Michelle H, Jacobs, William R

“…Abstract An attenuated Mycobacterium bovis RD1 deletion (Δ RD1 ) mutant of the Ravenel strain was constructed, characterized, and sequenced. This M. bovis Δ…”
Get full text

Failure of a Mycobacterium tuberculosis Δ RD1 Δ panCD double deletion mutant in a neonatal calf aerosol M. bovis challenge model: Comparisons to responses elicited by M. bovis bacille Calmette Guerin by Waters, W. Ray, Palmer, Mitchell V, Nonnecke, Brian J, Thacker, Tyler C, Scherer, Charles F. Capinos, Estes, D. Mark, Jacobs, William R, Glatman-Freedman, Aharona, Larsen, Michelle H

“…Abstract An attenuated Mycobacterium tuberculosis RD1 knockout and pantothenate auxotroph (mc2 6030) vaccine administered at 2 weeks of age failed to protect…”
Get full text

Application of Long-term cultured Interferon-γ Enzyme-linked Immunospot Assay for Assessing Effector and Memory T Cell Responses in Cattle by Maggioli, Mayara F, Palmer, Mitchell V, Vordermeier, H Martin, Whelan, Adam O, Fosse, James M, Nonnecke, Brian J, Waters, W Ray

“…Effector and memory T cells are generated through developmental programing of naïve cells following antigen recognition. If the infection is controlled up to…”
Get full text

An ESAT-6:CFP10 DNA vaccine administered in conjunction with Mycobacterium bovis BCG confers protection to cattle challenged with virulent M. bovis by Maue, Alexander C, Waters, W. Ray, Palmer, Mitchell V, Nonnecke, Brian J, Minion, F. Chris, Brown, Wendy C, Norimine, Junzo, Foote, Monica R, Scherer, Charles F.C, Estes, D. Mark

“…Abstract The potency of genetic immunization observed in the mouse has demonstrated the utility of DNA vaccines to induce cell-mediated and humoral immune…”
Get full text

Treatment of an intramammary bacterial infection with 25-hydroxyvitamin D3 by Lippolis, John D, Reinhardt, Timothy A, Sacco, Randy A, Nonnecke, Brian J, Nelson, Corwin D

“…Deficiency of serum levels of 25-hydroxyvitamin D3 has been correlated with increased risk of infectious diseases such as tuberculosis and influenza. A…”
Get full text

The calf model of immunity for development of a vaccine against tuberculosis by Endsley, Janice J., Waters, W. Ray, Palmer, Mitchell V., Nonnecke, Brian J., Thacker, Tyler C., Jacobs, William R., Larsen, Michelle H., Hogg, Alison, Shell, Elisabeth, McAlauy, Martin, Scherer, Charles F. Capinosh, Coffey, Tracey, Howard, Chris J., Villareal-Ramos, Bernardo, Estes, D. Mark

“…Tuberculosis (TB) remains a major threat to public health. The identification of safe TB vaccine candidates beyond Mycobacterium bovis BCG, is an exciting…”
Get full text

Safety and Immunogenicity of the Mycobacterium tuberculosis ΔlysA ΔpanCD Vaccine in Domestic Cats Infected with Feline Immunodeficiency Virus by Zimmerman, Dawn M., Waters, W. Ray, Lyashchenko, Konstantin P., Nonnecke, Brian J., Armstrong, Douglas L., Jacobs, William R., Larsen, Michelle H., Egan, Erin, Dean, Gregg A.

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Evaluation of Granulysin and Perforin as Candidate Biomarkers for Protection Following Vaccination with Mycobacterium bovis BCG or M. bovisΔRD1 by Capinos Scherer, Charles F, Endsley, Janice J, de Aguiar, Juliana B, Jacobs Jr, William R, Larsen, Michelle H, Palmer, Mitchell.V, Nonnecke, Brian J, Ray Waters, W, Mark Estes, D

“…The development of improved vaccines against tuberculosis (TB) is directly linked to the investigation of new and better correlates of protection after…”
Get full text

Serum 25-hydroxyvitamin D Concentrations in Captive and Free-ranging, White-tailed Deer (Odocoileus virginianus) by Waters, W. Ray, Nonnecke, Brian J, Gibbs, Samantha E.J, Yabsley, Michael J, Schmitt, Stephen M, Cosgrove, Melinda K, Palmer, Mitchell V, Thacker, Tyler C, Olsen, Steven C, Horst, Ronald L, Reinhardt, Timothy A

“…Serum concentrations of 25-hydroxyvitamin D [25(OH)D] were determined for free-ranging and captive white-tailed deer (WTD). Effects of gender, season, and age…”
Get full text