Search Results - "Nong, Keyi"
-
1
Advances in Research on the Toxicological Effects of Selenium
Published in Bulletin of environmental contamination and toxicology (01-05-2021)“…Selenium is a trace element necessary for the growth of organisms. Moreover, selenium supplementation can improve the immunity and fertility of the body, as…”
Get full text
Journal Article -
2
Effect of purple sweet potato-derived anthocyanins on heat stress response in Wenchang chickens and preliminary mechanism study
Published in Poultry science (01-09-2023)“…This study was conducted to investigate the beneficial effect of purple sweet potato anthocyanins (PSPA) on growth performance, oxidative status, immune…”
Get full text
Journal Article -
3
Effects of the Vitamin D3 on Alleviating the Oxidative Stress Induced by Diquat in Wenchang Chickens
Published in Animals (Basel) (01-02-2023)“…Vitamin D (VD ) is an indispensable micronutrient in livestock and poultry feed. Its function in antioxidant stress has been reported. We investigate whether…”
Get full text
Journal Article -
4
Discovery of Potent, Selective, and Direct Acid Sphingomyelinase Inhibitors with Antidepressant Activity
Published in Journal of medicinal chemistry (13-02-2020)“…Recent studies on sphingolipids suggest that acid sphingomyelinase (ASM), which plays a central role in the pathogenesis of major depression, is emerging to be…”
Get full text
Journal Article -
5
Discovery of N-hydroxy-3-alkoxybenzamides as direct acid sphingomyelinase inhibitors using a ligand-based pharmacophore model
Published in European journal of medicinal chemistry (10-05-2018)“…Acid sphingomyelinase (ASM) has been shown to be involved in many physiological processes, emerging to be a promising drug target. In this study, we…”
Get full text
Journal Article -
6
Human cathelicidin LL-37 exerts amelioration effects against EHEC O157:H7 infection regarding inflammation, enteric dysbacteriosis, and impairment of gut barrier function
Published in Peptides (New York, N.Y. : 1980) (01-01-2023)“…Enterohaemorrhagic Escherichia coli (EHEC) O157:H7 infection impairs intestinal barrier function, causing intestinal inflammation and enteric dysbacteriosis…”
Get full text
Journal Article -
7
3‑Acyl-4-Pyranone as a Lysine Residue-Selective Bioconjugation Reagent for Peptide and Protein Modification
Published in Bioconjugate chemistry (20-03-2024)“…Chemoselective protein modification plays extremely important roles in various biological, medical, and pharmaceutical investigations. Mimicking the mechanism…”
Get full text
Journal Article -
8
Potential effects and mechanism of flavonoids extract of Callicarpa nudiflora Hook on DSS-induced colitis in mice
Published in Phytomedicine (Stuttgart) (01-06-2024)“…•Flavonoids of C. Nudiflora is the potential drugs for the treatment of colitis.•Flavonoids of C. Nudiflora recoveres intestinal damage in mice.•Flavonoids of…”
Get full text
Journal Article -
9
Discovery of Novel N‑Hydroxy-1,2,4-oxadiazole-5-formamides as ASM Direct Inhibitors for the Treatment of Atherosclerosis
Published in Journal of medicinal chemistry (23-02-2023)“…Acid sphingomyelinase (ASM), which regulates sphingolipid metabolism and lipid signaling, has been considered as a new potential target for the treatment of…”
Get full text
Journal Article -
10
Regulation of the intestinal flora using polysaccharides from Callicarpa nudiflora Hook to alleviate ulcerative colitis and the molecular mechanisms involved
Published in International journal of biological macromolecules (01-02-2024)“…Ulcerative colitis (UC) is a type of inflammatory bowel disease (IBD) that cannot be completely cured by current treatments. C. nudiflora Hook has…”
Get full text
Journal Article -
11
The antimicrobial peptide Abaecin alleviates colitis in mice by regulating inflammatory signaling pathways and intestinal microbial composition
Published in Peptides (New York, N.Y. : 1980) (01-03-2024)“…Abaecin is a natural antimicrobial peptide (AMP) rich in proline from bees. It is an important part of the innate humoral immunity of bees and has…”
Get full text
Journal Article -
12
Effect of the Pseudopleuronectes americanus-derived Pleurocidin on DSS-induced Ulcerative colitis in mice and its preliminary molecular mechanisms
Published in International immunopharmacology (30-03-2024)“…In this study, we investigated the effect of Pleurocidin on ulcerative colitis in mice. The results showed that Pleurocidin ameliorated DSS-induced colon…”
Get full text
Journal Article -
13
Porcine-derived antimicrobial peptide PR39 alleviates DSS-induced colitis via the NF-κB/MAPK pathway
Published in International immunopharmacology (25-01-2024)“…PR39 is an antimicrobial peptide (AMP) with a variety of biological functions, including antimicrobial, wound healing, leukocyte chemotaxis, angiogenesis, and…”
Get full text
Journal Article