Search Results - "Nonaka, Kazuaki"
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Stem cells from human exfoliated deciduous teeth attenuate mechanical allodynia in mice through distinct from the siglec-9/MCP-1-mediated tissue-repairing mechanism
Published in Scientific reports (08-10-2021)“…The effects of stem cells from human exfoliated deciduous teeth (SHED) on mechanical allodynia were examined in mice. A single intravenous injection of SHED…”
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Therapeutic potential of hepatocyte-like-cells converted from stem cells from human exfoliated deciduous teeth in fulminant Wilson’s disease
Published in Scientific reports (07-02-2019)“…Wilson’s disease (WD) is an inherited metabolic disease arising from ATPase copper transporting beta gene ( ATP7B ) mutation. Orthotoropic liver…”
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Cryopreserved dental pulp tissues of exfoliated deciduous teeth is a feasible stem cell resource for regenerative medicine
Published in PloS one (14-12-2012)“…Human exfoliated deciduous teeth have been considered to be a promising source for regenerative therapy because they contain unique postnatal stem cells from…”
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Early Mortality and Morbidity in Infants with Birth Weight of 500 Grams or Less in Japan
Published in The Journal of pediatrics (01-11-2017)“…Objective To assess the short-term prognosis of Japanese infants with a birth weight (BW) of ≤500 g. Study design Demographic and clinical data were reviewed…”
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Folic acid-mediated mitochondrial activation for protection against oxidative stress in human dental pulp stem cells derived from deciduous teeth
Published in Biochemical and biophysical research communications (15-01-2019)“…Enzymatic antioxidant systems, mainly involving mitochondria, are critical for minimizing the harmful effects of reactive oxygen species, and these systems are…”
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Suppression of AKT-mTOR signal pathway enhances osteogenic/dentinogenic capacity of stem cells from apical papilla
Published in Stem cell research & therapy (29-11-2018)“…Stem cells from apical papilla (SCAP) are a subpopulation of mesenchymal stem cells (MSCs) isolated from the apical papilla of the developing tooth root apex…”
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Mitochondria Regulate the Differentiation of Stem Cells from Human Exfoliated Deciduous Teeth
Published in Cell Structure and Function (01-01-2017)“…Stem cells from human exfoliated deciduous teeth (SHED) are isolated from the dental pulp tissue of primary teeth and can differentiate into neuronal cells…”
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Acetylsalicylic Acid Treatment and Suppressive Regulation of AKT Accelerate Odontogenic Differentiation of Stem Cells from the Apical Papilla
Published in Journal of endodontics (01-05-2019)“…Stem cells isolated from the root apical papilla of human teeth (stem cells from the apical papilla [SCAPs]) are capable of forming tooth root dentin and are a…”
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Diurnal Variation of Human Sweet Taste Recognition Thresholds Is Correlated With Plasma Leptin Levels
Published in Diabetes (New York, N.Y.) (01-10-2008)“…Diurnal Variation of Human Sweet Taste Recognition Thresholds Is Correlated With Plasma Leptin Levels Yuki Nakamura 1 2 , Keisuke Sanematsu 1 , Rie Ohta 1 3 ,…”
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Direct effects of mitochondrial dysfunction on poor bone health in Leigh syndrome
Published in Biochemical and biophysical research communications (04-11-2017)“…Mitochondrial diseases are the result of aberrant mitochondrial function caused by mutations in either nuclear or mitochondrial DNA. Poor bone health has…”
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Interferon-gamma improves impaired dentinogenic and immunosuppressive functions of irreversible pulpitis-derived human dental pulp stem cells
Published in Scientific reports (18-01-2016)“…Clinically, irreversible pulpitis is treated by the complete removal of pulp tissue followed by replacement with artificial materials. There is considered to…”
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In vivo hepatogenic capacity and therapeutic potential of stem cells from human exfoliated deciduous teeth in liver fibrosis in mice
Published in Stem cell research & therapy (10-09-2015)“…Liver transplantation is a gold standard treatment for intractable liver diseases. Because of the shortage of donor organs, alternative therapies have been…”
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Adiponectin inhibits Toll-like receptor family-induced signaling
Published in FEBS letters (19-12-2005)“…Recent studies have shown that adiponectin, an adipocyte-derived cytokine, acts as a potent inhibitor of inflammatory responses. It has been also demonstrated…”
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Transplantation of mesenchymal stem cells ameliorates secondary osteoporosis through interleukin-17-impaired functions of recipient bone marrow mesenchymal stem cells in MRL/lpr mice
Published in Stem cell research & therapy (27-05-2015)“…Secondary osteoporosis is common in systemic lupus erythematosus and leads to a reduction in quality of life due to fragility fractures, even in patients with…”
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Pamidronate decreases bilirubin-impaired cell death and improves dentinogenic dysfunction of stem cells from human deciduous teeth
Published in Stem cell research & therapy (08-11-2018)“…Hyperbilirubinemia that occurs in pediatric liver diseases such as biliary atresia can result in the development of not only jaundice in the brain, eyes, and…”
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Regenerative medicine using stem cells from human exfoliated deciduous teeth (SHED): a promising new treatment in pediatric surgery
Published in Surgery today (Tokyo, Japan) (01-04-2019)Get full text
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Characterization and identification of subpopulations of mononuclear preosteoclasts induced by TNF-α in combination with TGF-β in rats
Published in PloS one (24-10-2012)“…Osteoclasts are unique multinucleated cells formed by fusion of preosteoclasts derived from cells of the monocyte/macrophage lineage, which are induced by…”
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Impaired neurite development associated with mitochondrial dysfunction in dopaminergic neurons differentiated from exfoliated deciduous tooth-derived pulp stem cells of children with autism spectrum disorder
Published in Biochemistry and biophysics reports (01-12-2018)“…Autism spectrum disorder (ASD) is a highly heterogeneous neurodevelopmental disorder characterized by impaired social interactions, restrictive interests, and…”
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Altered development of dopaminergic neurons differentiated from stem cells from human exfoliated deciduous teeth of a patient with Down syndrome
Published in BMC neurology (31-08-2018)“…Down syndrome (DS) is a common developmental disorder resulting from the presence of an additional copy of chromosome 21. Abnormalities in dopamine signaling…”
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Dihydroorotate dehydrogenase depletion hampers mitochondrial function and osteogenic differentiation in osteoblasts
Published in European journal of oral sciences (01-06-2016)“…Mutation of the dihydroorotate dehydrogenase (DHODH) gene is responsible for Miller syndrome, which is characterized by craniofacial malformations with limb…”
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