Search Results - "Nonaka, Carolina Vasques Kymie"

Exercise Training-Induced Changes in MicroRNAs: Beneficial Regulatory Effects in Hypertension, Type 2 Diabetes, and Obesity by Improta Caria, Alex Cleber, Nonaka, Carolina Kymie Vasques, Pereira, Ciro Silveira, Soares, Milena Botelho Pereira, Macambira, Simone Garcia, Souza, Bruno Solano de Freitas

“…MicroRNAs are small non-coding RNAs that regulate gene expression post-transcriptionally. They are involved in the regulation of physiological processes, such…”
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Modulation of MicroRNAs as a Potential Molecular Mechanism Involved in the Beneficial Actions of Physical Exercise in Alzheimer Disease by Improta-Caria, Alex Cleber, Nonaka, Carolina Kymie Vasques, Cavalcante, Bruno Raphael Ribeiro, De Sousa, Ricardo Augusto Leoni, Aras Júnior, Roque, Souza, Bruno Solano de Freitas

“…Alzheimer disease (AD) is one of the most common neurodegenerative diseases, affecting middle-aged and elderly individuals worldwide. AD pathophysiology…”
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SARS-CoV-2 variant of concern P.1 (Gamma) infection in young and middle-aged patients admitted to the intensive care units of a single hospital in Salvador, Northeast Brazil, February 2021 by Nonaka, Carolina Kymie Vasques, Gräf, Tiago, Barcia, Camila Araújo de Lorenzo, Costa, Vanessa Ferreira, de Oliveira, Janderson Lopes, Passos, Rogério da Hora, Bastos, Iasmin Nogueira, de Santana, Maria Clara Brito, Santos, Ian Marinho, de Sousa, Karoline Almeida Felix, Weber, Thamires Gomes Lopes, Siqueira, Isadora Cristina de, Rocha, Clarissa Araújo Gurgel, Mendes, Ana Verena Almeida, Souza, Bruno Solano de Freitas

“…•A second COVID-19 wave accelerated after the emergence of the P.1 lineage (Gamma).•An increased percentage of younger patients needed intensive care during…”
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Bone marrow-derived mesenchymal stem/stromal cells reverse the sensorial diabetic neuropathy via modulation of spinal neuroinflammatory cascades by Evangelista, Afrânio Ferreira, Vannier-Santos, Marcos André, de Assis Silva, Gessica Sabrina, Silva, Daniela Nascimento, Juiz, Paulo José Lima, Nonaka, Carolina Kymie Vasques, Dos Santos, Ricardo Ribeiro, Soares, Milena Botelho Pereira, Villarreal, Cristiane Flora

“…Diabetic neuropathy (DN) is a frequent and debilitating manifestation of diabetes mellitus, to which there are no effective therapeutic approaches. Mesenchymal…”
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Circulating miRNAs as Potential Biomarkers Associated with Cardiac Remodeling and Fibrosis in Chagas Disease Cardiomyopathy by Nonaka, Carolina Kymie Vasques, Macêdo, Carolina Thé, Cavalcante, Bruno Raphael Ribeiro, Alcântara, Adriano Costa de, Silva, Daniela Nascimento, Bezerra, Milena da Rocha, Caria, Alex Cleber Improta, Tavora, Fábio Rocha Fernandes, Neto, João David de Souza, Noya-Rabelo, Márcia Maria, Rogatto, Silvia Regina, Ribeiro Dos Santos, Ricardo, Souza, Bruno Solano de Freitas, Soares, Milena Botelho Pereira

“…Chagas disease (CD) affects approximately 6-7 million people worldwide, from which 30% develop chronic Chagas cardiomyopathy (CCC), usually after being…”
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Therapeutic miR-21 Silencing Reduces Cardiac Fibrosis and Modulates Inflammatory Response in Chronic Chagas Disease by Nonaka, Carolina Kymie Vasques, Sampaio, Gabriela Louise, Silva, Katia Nunes, Khouri, Ricardo, Macedo, Carolina Thé, Chagas Translational Research Consortium, Rogatto, Silvia Regina, Ribeiro Dos Santos, Ricardo, Souza, Bruno Solano de Freitas, Soares, Milena Botelho Pereira

“…Chagas disease, caused by the parasite ( ), remains a serious public health problem for which there is no effective treatment in the chronic stage. Intense…”
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Advances in Hepatic Tissue Bioengineering with Decellularized Liver Bioscaffold by Souza, Bruno Solano de Freitas, Nonaka, Carolina Kymie, Quintanilha, Luiz Fernando, Rossi, Erik Aranha

“…The burden of liver diseases continues to grow worldwide, and liver transplantation is the only option for patients with end-stage liver disease. This…”
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Early detection of P.1 variant of SARS-CoV-2 in a cluster of cases in Salvador, Brazil by de Siqueira, Isadora Cristina, Camelier, Aquiles Assunção, Maciel, Elves A.P., Nonaka, Carolina Kymie Vasques, Neves, Margarida Celia L.C., Macêdo, Yasmin Santos Freitas, de Sousa, Karoline Almeida Félix, Araujo, Victor Costa, Paste, Aurea Angelica, Souza, Bruno Solano de Freitas, Gräf, Tiago

“…•There is a cryptic transmission of the SARS-CoV-2 P.1 lineage across Brazil.•Genomic surveillance is important to track the emergence of SARS-CoV-2…”
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Is there a place for mesenchymal stromal cell-based therapies in the therapeutic armamentarium against COVID-19? by da Silva, Kátia Nunes, Gobatto, André Luiz Nunes, Costa-Ferro, Zaquer Suzana Munhoz, Cavalcante, Bruno Raphael Ribeiro, Caria, Alex Cleber Improta, de Aragão França, Luciana Souza, Nonaka, Carolina Kymie Vasques, de Macêdo Lima, Fernanda, Lopes-Pacheco, Miquéias, Rocco, Patricia Rieken Macêdo, de Freitas Souza, Bruno Solano

“…The COVID-19 pandemic, caused by the rapid global spread of the novel coronavirus (SARS-CoV-2), has caused healthcare systems to collapse and led to hundreds…”
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Therapeutic effects of sphingosine kinase inhibitor N,N-dimethylsphingosine (DMS) in experimental chronic Chagas disease cardiomyopathy by Vasconcelos, Juliana Fraga, Meira, Cássio Santana, Silva, Daniela Nascimento, Nonaka, Carolina Kymie Vasques, Daltro, Pâmela Santana, Macambira, Simone Garcia, Domizi, Pablo Daniel, Borges, Valéria Matos, Ribeiro-dos-Santos, Ricardo, de Freitas Souza, Bruno Solano, Soares, Milena Botelho Pereira

“…Chagas disease cardiomyopathy is a parasite-driven inflammatory disease to which there are no effective treatments. Here we evaluated the therapeutic potential…”
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Betulinic Acid Derivative BA5, Attenuates Inflammation and Fibrosis in Experimental Chronic Chagas Disease Cardiomyopathy by Inducing IL-10 and M2 Polarization by Meira, Cássio Santana, Santos, Emanuelle De Souza, Santo, Renan Fernandes do Espírito, Vasconcelos, Juliana Fraga, Orge, Iasmim Diniz, Nonaka, Carolina Kymie Vasques, Barreto, Breno Cardim, Caria, Alex Cleber Improta, Silva, Daniela Nascimento, Barbosa-Filho, José Maria, Macambira, Simone Garcia, Moreira, Diogo Rodrigo Magalhães, Soares, Milena Botelho Pereira

“…Chronic Chagas disease cardiomyopathy (CCC) is a major cause of heart disease in Latin America and treatment for this condition is unsatisfactory. Here we…”
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Generation of human iPS cell line CBTCi001-A from dermal fibroblasts obtained from a healthy donor by Martins, Gabriele Louise Soares, Paredes, Bruno Diaz, Sampaio, Gabriela Louise de Almeida, Nonaka, Carolina Kymie Vasques, da Silva, Katia Nunes, Allahdadi, Kyan James, França, Luciana Souza de Aragão, Soares, Milena Botelho Pereira, dos Santos, Ricardo Ribeiro, Souza, Bruno Solano de Freitas

“…Human-induced pluripotent stem cell (hiPSC) CBTCi001-A line was generated from a healthy 30-year old male dermal fibroblasts using non-integrative…”
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Generation of an induced pluripotent stem cell line from a patient with autism spectrum disorder and SCN2A haploinsufficiency by Sampaio, Gabriela Louise de Almeida, Martins, Gabriele Louise Soares, Paredes, Bruno Diaz, Nonaka, Carolina Kymie Vasques, da Silva, Katia Nunes, Rossi, Erik Aranha, dos Santos, Ricardo Ribeiro, Soares, Milena Botelho Pereira, Souza, Bruno Solano de Freitas

“…Autism spectrum disorders (ASDs) are a group of diseases that affect social interaction, communication and behavior. Molecular mechanisms involved in the…”
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Generation of three control iPS cell lines for sickle cell disease studies by reprogramming erythroblasts from individuals without hemoglobinopathies by Paredes, Bruno Diaz, Martins, Gabriele Louise Soares, Azevedo, Carine Machado, Sampaio, Gabriela Louise de Almeida, Nonaka, Carolina Kymie Vasques, Silva, Katia Nunes da, Soares, Milena Botelho Pereira, Santos, Ricardo Ribeiro dos, Souza, Bruno Solano de Freitas

“…Sickle cell disease (SCD) is one of the most prevalent and severe monogenetic disorders. Previously, we generated iPS cell lines from SCD patients. Here, we…”
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Immunomodulatory and Anti-fibrotic Effects Following the Infusion of Umbilical Cord Mesenchymal Stromal Cells in a Critically Ill Patient With COVID-19 Presenting Lung Fibrosis: A Case Report by Silva, Kátia Nunes da, Pinheiro, Priscila Carvalho Guedes, Gobatto, André Luiz Nunes, Passos, Rogério da Hora, Paredes, Bruno Diaz, França, Luciana Souza de Aragão, Nonaka, Carolina Kymie Vasques, Barreto-Duarte, Beatriz, Araújo-Pereira, Mariana, Tibúrcio, Rafael, Cruz, Fernanda Ferreira, Martins, Gabriele Louise Soares, Andrade, Bruno B., Castro-Faria-Neto, Hugo Caire de, Rocco, Patricia Rieken Macêdo, Souza, Bruno Solano de Freitas

“…Background: The patients with coronavirus disease 2019 (COVID-19) associated with severe acute respiratory distress syndrome (ARDS) may require prolonged…”
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Generation of integration-free iPS cell lines from three sickle cell disease patients from the state of Bahia, Brazil by Martins, Gabriele Louise Soares, Paredes, Bruno Diaz, Azevedo, Carine Machado, Sampaio, Gabriela Louise De Almeida, Nonaka, Carolina Kymie Vasques, Cavalcante, Bruno Raphael Ribeiro, Da Silva, Katia Nunes, Pereira, Ciro Silveira E., Soares, Milena Botelho Pereira, Dos Santos, Ricardo Ribeiro, Souza, Bruno Solano De Freitas

“…Sickle cell disease (SCD) is one of the most prevalent and severe monogenetic disorders, affecting several million people around the world. Clinical…”
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Different methods of real-time PCR for detection of pseudorabies virus by Nonaka, Carolina Kymie Vasques, Fonseca Junior, Antônio Augusto, Guedes, Estefânia Oliveira, D´Ambros, Régia Maria, Lima, Graciela Kunrath, Camargos, Marcelo Fernandes, Heinemann, Marcos Bryan

“…Pseudorabies (PR) is a highly contagious viral disease of great animal health and economic importance in swine industry. The aim of this study was to evaluate…”
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Genomic Evidence of SARS-CoV-2 Reinfection Involving E484K Spike Mutation, Brazil by Nonaka, Carolina K V, Franco, Marília Miranda, Gräf, Tiago, de Lorenzo Barcia, Camila Araújo, de Ávila Mendonça, Renata Naves, de Sousa, Karoline Almeida Felix, Neiva, Leila M C, Fosenca, Vagner, Mendes, Ana V A, de Aguiar, Renato Santana, Giovanetti, Marta, de Freitas Souza, Bruno Solano

“…Uncertainty remains about how long the protective immune responses against severe acute respiratory syndrome coronavirus 2 persists, and suspected reinfection…”
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The Phytochemical Agathisflavone Modulates miR146a and miR155 in Activated Microglia Involving STAT3 Signaling by Dos Santos, Balbino Lino, Dos Santos, Cleonice Creusa, da Silva, Karina Costa, Nonaka, Carolina Kymie Vasques, Souza, Bruno Solano de Freitas, David, Jorge Mauricio, de Oliveira, Juciele Valéria Ribeiro, Costa, Maria de Fátima Dias, Butt, Arthur Morgan, da Silva, Victor Diogenes Amaral, Costa, Silvia Lima

“…MicroRNAs (miRs) act as important post-transcriptional regulators of gene expression in glial cells and have been shown to be involved in the pathogenesis of…”
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Tolerogenic Dendritic Cells Reduce Cardiac Inflammation and Fibrosis in Chronic Chagas Disease by Santos, Emanuelle de Souza, de Aragão-França, Luciana Souza, Meira, Cássio Santana, Cerqueira, Jéssica Vieira, Vasconcelos, Juliana Fraga, Nonaka, Carolina Kymie Vasques, Pontes-de-Carvalho, Lain Carlos, Soares, Milena Botelho Pereira

“…Chronic Chagas disease cardiomyopathy (CCC) is the most frequent and severe form of this parasitic disease. CCC is caused by a progressive inflammation in the…”
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