Search Results - "Nomura, Tamotsu"

Arachidonic Acid as a Messenger for the Expression of Long-Term Potentiation by Nishizaki, Tomoyuki, Nomura, Tamotsu, Matsuoka, Toshiyuki, Tsujishita, Yosuke

“…Arachidonic acid is suggested to play a role in the expression of long-term potentiation (LTP), a synaptic analog of memory and learning. However, it is…”
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A `long-term-potentiation-like' facilitation of hippocampal synaptic transmission induced by the nootropic nefiracetam by Nishizaki, Tomoyuki, Matsuoka, Toshiyuki, Nomura, Tamotsu, Matsuyama, Shogo, Watabe, Shigeo, Shiotani, Tadashi, Yoshii, Mitsunobu

“…Nefiracetam, a nootropic agent, enhanced the slope of field excitatory postsynaptic potentials in the CA1 region of rat hippocampal slices to about 170% of…”
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Canadian and Japanese Laws Concerning the Protection of Privacy and Personal Information in the Private Sector: A Comparative Study by Nomura, Tamotsu

“…With the progression and spread of information technologies, personal information is being used innovatively to increase individual, social, and economic…”
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Arachidonic acid induces a long-lasting facilitation of hippocampal synaptic transmission by modulating PKC activity and nicotinic ACh receptors by Nishizaki, Tomoyuki, Nomura, Tamotsu, Matsuoka, Toshiyuki, Enikolopov, Grigori, Sumikawa, Katumi

“…The present study was conducted to understand the effect of arachidonic acid on nicotinic acetylcholine (ACh) receptor-mediated synaptic plasticity…”
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Presynaptic nicotinic acetylcholine receptors as a functional target of Nefiracetam in inducing a long-lasting facilitation of hippocampal neurotransmission by NISHIZAKI, T, MATSUOKA, T, NOMURA, T, KONDOH, T, WATABE, S, SHIOTANI, T, YOSHII, M

“…Nefiracetam (1-10 microM), a nootropic (or cognition-enhancing) agent, persistently potentiated currents through Torpedo acetylcholine (ACh) receptors…”
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Modulation of ACh receptor currents by arachidonic acid by Nishizaki, Tomoyuki, Matsuoka, Toshiyuki, Nomura, Tamotsu, Sumikawa, Katumi

“…The present study investigated the effects of arachidonic acid on Torpedo ( αβγδ) and neuronal nicotinic acetylcholine (ACh) receptors (chick α7; rat α7, α3…”
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Critical Role of Presynaptic Nicotinic ACh Receptor in the Formation of Long-Term Potentiation: Implications for Development of Anti-Dementia Drugs by Nishizaki, Tomoyuki, Nomura, Tamotsu, Matsuyama, Shogo, Kondoh, Takeshi, Fujimoto, Etsuko, Yoshii, Mitsunobu

“…Background: Since neuronal nicotinic ACh receptors are involved in the cognitive function, they have been studied as a target of anti‐dementia drugs. The…”
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Erratum to “The anti-dementia drug nefiracetam facilitates hippocampal synaptic transmission by functionally targeting presynaptic nicotinic ACh receptors” [Molecular Brain Res. 80 (2000) 53–62] by Nishizaki, Tomoyuki, Nomura, Tamotsu, Matuoka, Toshiyuki, Kondoh, Takeshi, Enikolopo, Grigori, Sumikawa, Katumi, Watabe, Shigeo, Shiotani, Tadashi, Yoshii, Mitsunobu

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Nefiracetam facilitates hippocampal neurotransmission by a mechanism independent of the piracetam and aniracetam action by Nomura, Tamotsu, Nishizaki, Tomoyuki

“…Nefiracetam, a nootropic (cognition-enhancing) agent, facilitated neurotransmission in the dentate gyrus of rat hippocampal slices in a dose-dependent manner…”
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Nefiracetam induces a long-lasting facilitation of hippocampal postsynaptic responses in mice lacking the NMDA receptor ϵ1 subunit by Matsumoto, Shinji, Kanno, Takeshi, Nomura, Tamotsu, Shiotani, Tadashi, Watabe, Sigeo, Nabeshima, Toshitaka, Nishizaki, Tomoyuki

“…The present study was designed to assess whether the facilitatory action of nefiracetam, a pyrrolidone derivative, on hippocampal postsynaptic responses is…”
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Nefiracetam induces a long-lasting facilitation of hippocampal postsynaptic responses in mice lacking the NMDA receptor epsilon1 subunit by Matsumoto, Shinji, Kanno, Takeshi, Nomura, Tamotsu, Shiotani, Tadashi, Watabe, Sigeo, Nabeshima, Toshitaka, Nishizaki, Tomoyuki

“…The present study was designed to assess whether the facilitatory action of nefiracetam, a pyrrolidone derivative, on hippocampal postsynaptic responses is…”
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Nefiracetam modulates acetylcholine receptor currents via two different signal transduction pathways by Nishizaki, T, Matsuoka, T, Nomura, T, Sumikawa, K, Shiotani, T, Watabe, S, Yoshii, M

“…Nootropic agents are proposed to serve as cognition enhancers. The underlying mechanism, however, is largely unknown. The present study was conducted to assess…”
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Nefiracetam induces a long-lasting facilitation of hippocampal postsynaptic responses in mice lacking the NMDA receptor ∈1 subunit by MATSUMOTO, Shinji, KANNO, Takeshi, NOMURA, Tamotsu, SHIOTANI, Tadashi, WATABE, Sigeo, NABESHIMA, Toshitaka, NISHIZAKI, Tomoyuki

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Sustained facilitatory action of FK960 on hippocampal neurotransmission by Matsuyama, Shogo, Nomura, Tamotsu, Nishizaki, Tomoyuki

“…The present study investigated the effect of N-(4-acetyl-1-piperazinyl)- p-fluorobenzamide monohydrate (FK960), a piperazine derivative developed as…”
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l- trans-PDC enhances hippocampal neuronal activity by stimulating glial glutamate release independently of blocking transporters by Ohta, Kohei, Nomura, Tamotsu, Kanno, Takeshi, Nagai, Kaoru, Yamamoto, Satoshi, Yajima, Yukio, Kondoh, Takeshi, Kohmura, Eiji, Saito, Naoaki, Nishizaki, Tomoyuki

“…The glutamate transporter inhibitor, l- trans-pyrrolidine-2,4-dicarboxylic acid (PDC) reversibly enhanced hippocampal neuronal activity in the rat and mouse…”
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Store Ca2+ Depletion Enhances NMDA Responses in Cultured Human Astrocytes by Nishizaki, Tomoyuki, Matsuoka, Toshiyuki, Nomura, Tamotsu, Kondoh, Takeshi, Tamaki, Norihiko, Okada, Yasuhiro

“…NMDA produced whole-cell membrane currents in cultured human astrocytes. The currents were not inhibited by the selective NMDA receptor antagonist, APV, while…”
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The Voltage-Dependent Non-selective Cation Channel Sensitive to the L-Type Calcium Channel Blocker Efonidipine Regulates Ca 2+Influx in Brain Vascular Smooth Muscle Cells by Matsuoka, Toshiyuki, Nishizaki, Tomoyuki, Nomura, Tamotsu

“…The present study investigated the ion channel responsible Ca 2+influx in cultured smooth muscle cells from bovine brain arteries by monitoring Ba 2+currents…”
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Store Ca Depletion Enhances NMDA Responses in Cultured Human Astrocytes by Nishizaki, T, Matsuoka, T, Nomura, T, Kondoh, T, Tamaki, N, Okada, Y

“…NMDA produced whole-cell membrane currents in cultured human astrocytes. The currents were not inhibited by the selective NMDA receptor antagonist, APV, while…”
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Cerebral aneurysm occurrence prediction by morphometric analysis of the Willis ring by Yasugi, Marin, Hossain, Belayat, Shibutani, Hironobu, Nomura, Tamotsu, Nii, Manabu, Morimoto, Masakazu, Kobashi, Syoji

“…It is known that lifestyle habit and genetic factor are main reasons that occur cerebral aneurysms. In addition, some studies suggest that cerebral artery…”
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Methamphetamine modulates ACh-evoked currents in Xenopus oocytes expressing the rat α7 receptors by Nomura, Tamotsu, Nishizaki, Tomoyuki

“…Although the cholinergic system is proposed to be involved in methamphetamine (MeAMPH)-induced abnormal behaviors, no direct evidence has been provided yet…”
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