Search Results - "Nomura, Naho"

Essential role of autophagy in protecting neonatal haematopoietic stem cells from oxidative stress in a p62-independent manner by Nomura, Naho, Ito, Chiaki, Ooshio, Takako, Tadokoro, Yuko, Kohno, Susumu, Ueno, Masaya, Kobayashi, Masahiko, Kasahara, Atsuko, Takase, Yusuke, Kurayoshi, Kenta, Si, Sha, Takahashi, Chiaki, Komatsu, Masaaki, Yanagawa, Toru, Hirao, Atsushi

“…Autophagy is a cellular degradation system contributing to homeostasis of tissue stem cells including haematopoietic stem cells (HSCs). It plays pleiotropic…”
Get full text

Distinct roles of Rheb and Raptor in activating mTOR complex 1 for the self-renewal of hematopoietic stem cells by Peng, Hui, Kasada, Atsuo, Ueno, Masaya, Hoshii, Takayuki, Tadokoro, Yuko, Nomura, Naho, Ito, Chiaki, Takase, Yusuke, Vu, Ha Thi, Kobayashi, Masahiko, Xiao, Bo, Worley, Paul F., Hirao, Atsushi

“…The mammalian target of rapamycin (mTOR) complex 1 (mTORC1) senses a cell's energy status and environmental levels of nutrients and growth factors. In…”
Get full text

Autophagy inhibition synergizes with calcium mobilization to achieve efficient therapy of malignant gliomas by Vu, Ha Thi, Kobayashi, Masahiko, Hegazy, Ahmed M., Tadokoro, Yuko, Ueno, Masaya, Kasahara, Atsuko, Takase, Yusuke, Nomura, Naho, Peng, Hui, Ito, Chiaki, Ino, Yasushi, Todo, Tomoki, Nakada, Mitsutoshi, Hirao, Atsushi

“…Autophagy plays a critical role in tumorigenesis, but how autophagy contributes to cancer cells’ responses to chemotherapeutics remains controversial. To…”
Get full text

Venetoclax-Azacitidine Bridging PTCy-haplo-PBSCT for Refractory Acute Myeloid Leukemia with IDH2 Mutations by Daido, Yusuke, Sugiura, Hiroyuki, Ishikawa, Tatsunori, Kuroi, Taiga, Okamoto, Sachiyo, Nomura, Naho, Masunari, Taro, Sezaki, Nobuo, Nannya, Yasuhito, Ogawa, Seishi, Tanimoto, Mitsune

“…Abstract Venetoclax and azacitidine combination therapy (VEN+AZA) is a promising novel therapy for elderly or unfit patients with acute myeloid leukemia (AML)…”
Get full text

Successful treatment of relapsed chronic lymphocytic leukemia with venetoclax in a patient with severe chronic kidney disease by Sugiura, Hiroyuki, Sezaki, Nobuo, Ishikawa, Tatsunori, Kuroi, Taiga, Okamoto, Sachiyo, Nomura, Naho, Masunari, Taro, Nakasako, Yukio, Kiguchi, Toru, Tanimoto, Mitsune

“…Venetoclax is a promising new drug for relapsed or refractory chronic lymphocytic leukemia (CLL). However, venetoclax use had not been reported in severe…”
Get full text

Concurrent Onset of Chronic Lymphocytic Leukemia and Atypical Phenotype Acute Myeloid Leukemia Revealed by Autopsy by Kiso, Sayaka, Sugiura, Hiroyuki, Kuroi, Taiga, Omote, Rika, Toji, Tomohiro, Ishikawa, Tatsunori, Okamoto, Sachiyo, Nomura, Naho, Masunari, Taro, Sezaki, Nobuo, Kiguchi, Toru, Tanimoto, Mitsune

“…Abstract The concurrent onset of chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML) is rare, and no autopsy case has been reported. We report…”
Get full text

Comparison of disease and risk classifications of AML before and after incorporation of NGS analysis of bone marrow samples by Sugiura, Hiroyuki, Ishikawa, Tatsunori, Kuroi, Taiga, Okamoto, Sachiyo, Nomura, Naho, Masunari, Taro, Sezaki, Nobuo, Ogawa, Seishi, Nannya, Yasuhito, Makita, Masanori

“…Mutation profiling by next-generation sequencing (NGS) has facilitated understanding of the molecular pathogenesis of acute myeloid leukemia (AML), and has…”
Get full text

First report of familial mixed phenotype acute leukemia: shared clinical characteristics, Philadelphia translocation, and germline variants by Shiozawa, Yuka, Fujita, Shinya, Nannya, Yasuhito, Ogawa, Seishi, Nomura, Naho, Kiguchi, Toru, Sezaki, Nobuo, Kudo, Himari, Toyama, Takaaki

“…While our understanding of the molecular basis of mixed phenotype acute leukemia (MPAL) has progressed over the decades, our knowledge is limited and the…”
Get full text

Potential Mechanisms of Improvement of Airway Hyperresponsiveness by Inhaled Corticosteroid Therapy in Asthmatic Patients by Nomura, Saeko, Kanazawa, Hi roshi, Asai, Kazuhisa, Nomura, Naho, Hirata, Kazuto, Yoshikawa, Junichi

“…Objective. Recent clinical trials with administration of IL-5 antibodies to asthmatic patients have revealed reduction of eosinophilia but unaltered airway…”
Get full text

Functional dissection of hematopoietic stem cell populations with a stemness-monitoring system based on NS-GFP transgene expression by Ali, Mohamed A. E., Fuse, Kyoko, Tadokoro, Yuko, Hoshii, Takayuki, Ueno, Masaya, Kobayashi, Masahiko, Nomura, Naho, Vu, Ha Thi, Peng, Hui, Hegazy, Ahmed M., Masuko, Masayoshi, Sone, Hirohito, Arai, Fumio, Tajima, Atsushi, Hirao, Atsushi

“…Hematopoietic stem cells (HSCs) in a steady state can be efficiently purified by selecting for a combination of several cell surface markers; however, such…”
Get full text

Risk assessment for outpatients for cancer chemotherapy by Uramoto, Hidetaka, Ichiki, Takaharu, Shinohara, Yoshinori, Kabashima, Misako, Yamazaki, Kayoko, Kadota, Tomoko, Nomura, Naho, Iwashige, Atsushi, Kagami, Seiji, Tsukada, Junichi

“…Outpatient treatment in the cancer chemotherapy center was begun in April 2005 at the University of Occupational and Environmental Health Hospital. Drugs were…”
Get more information

Impaired Neutrophil Chemotaxis in Chronic Obstructive Pulmonary Disease by Yoshikawa, Takahiro, Dent, Gordon, Ward, Jon, Angco, Gilbert, Nong, Guangmin, Nomura, Naho, Hirata, Kazuto, Djukanovic, Ratko

“…Neutrophilic airway inflammation is considered to be a major factor in the pathogenesis of chronic obstructive pulmonary disease (COPD), with sputum and…”
Get full text

Lipopolysaccharide(LPS)-Induction of the HTLV-1 LTR in Monocytes by Tsukada, Junichi, Higashi, Takehiro, Iwashige, Atsushi, Katsuragi, Takefumi, Nomura, Naho, Yamaguchi, Takahiro, Nakanishi, Tsukasa, Kitamura, Noriaki, Kawahara, Ai, Yoshida, Yasuhiro, Morimoto, Hiroaki

“…Abstract 2167 The human leukemia virus type 1 (HTLV-1) gene expression is regulated by the viral proteins and various cellular transcription factors. HTLV-1…”
Get full text

Analysis of vascular endothelial growth factor levels in induced sputum samples from patients with cough variant asthma by Kanazawa, Hiroshi, Eguchi, Yohsuke, Nomura, Naho, Yoshikawa, Junichi

“…We previously found that vascular endothelial growth factor (VEGF) levels in induced sputum samples are increased in patients with classic asthma and are…”
Get more information

Induced sputum analysis in asymptomatic young adults with bronchial hyperresponsiveness to methacholine by NOMURA, Naho, YOSHIKAWA, Takahiro, KAMOI, Hiroshi, KANAZAWA, Hiroshi, HIRATA, Kazuto, FUJIMOTO, Shigeo

“…Background and objectives:  BHR is a clinical feature of asthma and factors crucial to the development of BHR remain to be elucidated. Asymptomatic BHR also…”
Get full text

Successful treatment of relapsed chronic lymphocytic leukemia with venetoclax in a patient with severe chronic kidney disease by Sugiura, Hiroyuki, Sezaki, Nobuo, Ishikawa, Tatsunori, Kuroi, Taiga, Okamoto, Sachiyo, Nomura, Naho, Masunari, Taro, Nakasako, Yukio, Kiguchi, Toru, Tanimoto, Mitsune

Get full text

Venetoclax-Azacitidine Bridging PTCy-haplo-PBSCT for Refractory Acute Myeloid Leukemia with IDH2 Mutations by Daido, Yusuke, Sugiura, Hiroyuki, Ishikawa, Tatsunori, Kuroi, Taiga, Okamoto, Sachiyo, Nomura, Naho, Masunari, Taro, Sezaki, Nobuo, Nannya, Yasuhito, Ogawa, Seishi, Tanimoto, Mitsune

“…Venetoclax and azacitidine combination therapy (VEN+AZA) is a promising novel therapy for elderly or unfit patients with acute myeloid leukemia (AML)…”
Get full text

Concurrent Onset of Chronic Lymphocytic Leukemia and Atypical Phenotype Acute Myeloid Leukemia Revealed by Autopsy by Kiso, Sayaka, Sugiura, Hiroyuki, Kuroi, Taiga, Omote, Rika, Toji, Tomohiro, Ishikawa, Tatsunori, Okamoto, Sachiyo, Nomura, Naho, Masunari, Taro, Sezaki, Nobuo, Kiguchi, Toru, Tanimoto, Mitsune

“…The concurrent onset of chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML) is rare, and no autopsy case has been reported. We report herein…”
Get full text