Search Results - "Nompari, Luca"
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Optimization of hydrolysis conditions of amino acid analysis for UHPLC-UV antigens content determination: Bexsero vaccine a case study
Published in Journal of pharmaceutical and biomedical analysis (15-04-2024)“…In the present study the compositional analysis of the amino acids released by the acidic hydrolysis of the vaccine antigens was approached as an alternative…”
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Quality by design approach in the development of an ultra-high-performance liquid chromatography method for Bexsero meningococcal group B vaccine
Published in Talanta (Oxford) (01-02-2018)“…Bexsero is the first approved vaccine for active immunization of individuals from 2 months of age and older to prevent invasive disease caused by Neisseria…”
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Glycoconjugate content quantification to assess vaccine potency: A simplified approach
Published in Biologicals (01-04-2022)“…Several glycoconjugate vaccines have been licensed or are currently in clinical development to prevent bacterial infections. Here we report the development of…”
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Innovative Reversed-Phase Chromatography Platform Approach for the Fast and Accurate Characterization of Membrane Vesicles’ Protein Patterns
Published in ACS pharmacology & translational science (10-05-2024)“…Outer membrane vesicles (OMVs) have been widely explored to develop vaccine candidates for bacterial pathogens due to their ability to combine adjuvant…”
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Development of a New Solid-Phase Extraction Base Method for Free Saccharide Content Estimation of Meningococcal Conjugate Vaccines
Published in ACS omega (08-11-2022)“…GlaxoSmithKline (GSK) is currently developing a fully liquid presentation to ease the administration of the licensed quadrivalent conjugate vaccine (Menveo)…”
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