Search Results - "Noll, Alyssa"

Neuronal Activity Promotes Glioma Growth through Neuroligin-3 Secretion by Venkatesh, Humsa S., Johung, Tessa B., Caretti, Viola, Noll, Alyssa, Tang, Yujie, Nagaraja, Surya, Gibson, Erin M., Mount, Christopher W., Polepalli, Jai, Mitra, Siddhartha S., Woo, Pamelyn J., Malenka, Robert C., Vogel, Hannes, Bredel, Markus, Mallick, Parag, Monje, Michelle

“…Active neurons exert a mitogenic effect on normal neural precursor and oligodendroglial precursor cells, the putative cellular origins of high-grade glioma…”
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Therapeutic HDAC inhibition in hypermutant diffuse intrinsic pontine glioma by Noll, Alyssa, Myers, Carrie, Biery, Matthew C, Meechan, Michael, Tahiri, Sophie, Rajendran, Asmitha, Berens, Michael E, Paine, Danyelle, Byron, Sara, Zhang, Jiaming, Winter, Conrad, Pakiam, Fiona, Leary, Sarah E S, Cole, Bonnie L, Jackson, Evangeline R, Dun, Matthew D, Foster, Jessica B, Evans, Myron K, Pattwell, Siobhan S, Olson, James M, Vitanza, Nicholas A

“…Constitutional mismatch repair deficiency (CMMRD) is a cancer predisposition syndrome associated with the development of hypermutant pediatric high-grade…”
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DIPG-58. Therapeutic HDAC targeting in hypermutant CNS tumors by Myers, Carrie, Noll, Alyssa, Biery, Matthew, Meechan, Michael, Tahiri, Sophie, Foster, Jessica, Dun, Matthew, Olson, James, Vitanza, Nicholas

“…Abstract Diffuse intrinsic pontine glioma (DIPG) is a universally fatal tumor of the pons, most often characterized by mutations in genes encoding histone 3,…”
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MODL-28. IMMUNE PRIMING WITH INTERFERON-Γ COMBINED WITH EPIGENETIC MODULATION IN PEDIATRIC BRAIN TUMORS by Crotty, Erin, Morris, Shelli, Brasel, Ken, Girard, Emily, Noll, Alyssa, Mhyre, Andrew, Olson, James

“…Abstract Systemic interferon-γ (IFNγ) has been shown to induce major histocompatibility complex class I (MHC-I) and T cell infiltration in solid tumors in…”
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Optimal therapeutic targeting by HDAC inhibition in biopsy-derived treatment-naïve diffuse midline glioma models by Vitanza, Nicholas A, Biery, Matt C, Myers, Carrie, Ferguson, Eric, Zheng, Ye, Girard, Emily J, Przystal, Justyna M, Park, Giulia, Noll, Alyssa, Pakiam, Fiona, Winter, Conrad A, Morris, Shelli M, Sarthy, Jay, Cole, Bonnie L, Leary, Sarah E S, Crane, Courtney, Lieberman, Nicole A P, Mueller, Sabine, Nazarian, Javad, Gottardo, Raphael, Brusniak, Mi-Youn, Mhyre, Andrew J, Olson, James M

“…Abstract Background Diffuse midline gliomas (DMGs), including diffuse intrinsic pontine gliomas (DIPGs), have a dismal prognosis, with less than 2% surviving 5…”
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Abstract 4740: Molecular effects of histone deacetylase inhibitor Quisinostat on diffuse midline glioma of the pons by Paine, Danyelle, Tang, Nanyun, Hao, Yue, Biery, Matt, Meyers, Carrie, Noll, Alyssa, Vitanza, Nicholas, Berens, Michael

“…Abstract Diffuse Midline Glioma of the pons (DMG) is a lethal, aggressive heterogeneous brain stem tumor. Median overall survival is less than a year, with…”
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DIPG-10. OPTIMAL HDAC INHIBITION IN DIFFUSE INTRINSIC PONTINE GLIOMA by Vitanza, Nicholas, Biery, Matt, Myers, Carrie, Ferguson, Eric, Park, Giulia, Noll, Alyssa, Pakiam, Fiona, Girard, Emily, Morris, Shelli, Cole, Bonnie, Brusniak, Mi-Youn, Mhyre, Andrew, Olson, James

“…Abstract As the majority of diffuse intrinsic pontine glioma (DIPG) have H3K27M mutations, epigenetic-targeting agents have been studied, though evaluations…”
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EXTH-58. THERAPEUTIC HDAC INHIBITION IN HYPERMUTANT DIFFUSE INTRINSIC PONTINE GLIOMA by Noll, Alyssa, Biery, Matt, Myers, Carrie, Paine, Danyelle, Zheng, Ye, Girard, Emily, Winter, Conrad, Morris, Shelli, Brusniak, Mi-Youn, Gottardo, Raphael, Mhyre, Andrew, Foster, Jessica, Dun, Matthew, Murtaza, Muhammed, Berens, Michael, Olson, James, Vitanza, Nicholas

“…Abstract Diffuse intrinsic pontine glioma (DIPG) continues to carry a dismal prognosis despite a growing understanding of its epigenetic regulation. While…”
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ME-08NEURONS PROMOTE GLIOMA GROWTH IN AN ACTIVITY-DEPENDENT MANNER by Johung, Tessa, Venkatesh, Humsa, Caretti, Viola, Noll, Alyssa, Monje, Michelle

“…Pediatric high-grade gliomas (pHGG) are the leading cause of brain tumor death in children. Mounting evidence indicates that oligodendrocyte precursor cells…”
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Neuronal activity-regulated secretion of neuroligin-3 promotes glioma growth (S43.003) by Monje, Michelle, Venkatesh, Humsa, Caretti, Viola, Johung, Tessa, Noll, Alyssa, Vogel, Hannes, Mallick, Parag, Bredel, Markus

“…Abstract only…”
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DIPG-35. A NOVEL HDAC INHIBITOR IN NEW PATIENT-DERIVED DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) MODELS by Biery, Matthew, Myers, Carrie, Girard, Emily, Morris, Shelli, Carmack, Savanna, Noll, Alyssa, Sarthy, Jay, Ferguson, Eric, Mhyre, Andrew, Strand, Andrew, Olson, James, Vitanza, Nicholas

“…Abstract Diffuse intrinsic pontine glioma (DIPG) remains a universally fatal childhood cancer with a median survival of less than 1 year. Focal radiation…”
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HG-04NEURONAL ACTIVITY-REGULATED SECRETION OF NEUROLIGIN-3 PROMOTES GLIOMA GROWTH by Venkatesh, Humsa, Johung, Tessa, Caretti, Viola, Noll, Alyssa, Vogel, Hannes, Bredel, Markus, Mallick, Parag, Monje, Michelle

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ME-08 NEURONS PROMOTE GLIOMA GROWTH IN AN ACTIVITY-DEPENDENT MANNER by Johung, T., Venkatesh, H., Caretti, V., Noll, A., Monje, M.

“…Pediatric high-grade gliomas (pHGG) are the leading cause of brain tumor death in children. Mounting evidence indicates that oligodendrocyte precursor cells…”
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