Search Results - "Nolan, Yvonne"
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Neuroinflammation negatively affects adult hippocampal neurogenesis and cognition: can exercise compensate?
Published in Neuroscience and biobehavioral reviews (01-02-2016)“…Adult hippocampal neurogenesis is believed to be integral for certain forms of learning and memory. Dysregulation of hippocampal neurogenesis has been shown to…”
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Depression's Unholy Trinity: Dysregulated Stress, Immunity, and the Microbiome
Published in Annual review of psychology (04-01-2020)“…Depression remains one of the most prevalent psychiatric disorders, with many patients not responding adequately to available treatments. Chronic or early-life…”
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Inflammation, Lifestyle Factors, and the Microbiome‐Gut‐Brain Axis: Relevance to Depression and Antidepressant Action
Published in Clinical pharmacology and therapeutics (01-02-2023)“…Depression is considered a major public health concern, where existing pharmacological treatments are not equally effective across all patients. The…”
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Born this way: Hippocampal neurogenesis across the lifespan
Published in Aging cell (01-10-2019)“…The capability of the mammalian brain to generate new neurons through the lifespan has gained much attention for the promise of new therapeutic possibilities…”
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Toxoplasma gondii: An unwelcome visitor that damages social and neuronal connections
Published in Brain, behavior, and immunity (01-08-2019)Get full text
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Inflammation and the developing brain: Consequences for hippocampal neurogenesis and behavior
Published in Neuroscience and biobehavioral reviews (01-03-2014)“…While the detrimental impact of inflammation on adult hippocampal neurogenesis and associated behaviors has recently gained credence, the effects of…”
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Contributions of central and systemic inflammation to the pathophysiology of Parkinson's disease
Published in Neuropharmacology (01-06-2012)“…Idiopathic Parkinson's disease (PD) represents a complex interaction between the inherent vulnerability of the nigrostriatal dopaminergic system, a possible…”
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Microbiota from Alzheimer's patients induce deficits in cognition and hippocampal neurogenesis
Published in Brain (London, England : 1878) (01-12-2023)“…Alzheimer's disease is a complex neurodegenerative disorder leading to a decline in cognitive function and mental health. Recent research has positioned the…”
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Parkinson's disease in the nuclear age of neuroinflammation
Published in Trends in molecular medicine (01-03-2013)“…Chronic neuroinflammation is associated with the pathophysiology of Parkinson's disease, a movement disorder characterised by deterioration of the…”
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Outrunning a bad diet: Interactions between exercise and a Western-style diet for adolescent mental health, metabolism and microbes
Published in Neuroscience and biobehavioral reviews (01-06-2023)“…Adolescence is a period of biological, psychological and social changes, and the peak time for the emergence of mental health problems. During this life stage,…”
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The gut microbiome and adult hippocampal neurogenesis: A new focal point for epilepsy?
Published in Neurobiology of disease (01-08-2022)“…Temporal lobe epilepsy (TLE) is a neurological disorder affecting millions of people worldwide and currently represents the most common form of focal epilepsy…”
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The influence of microglia on the pathogenesis of Parkinson's disease
Published in Progress in neurobiology (01-11-2009)“…Parkinson's disease (PD) is characterised by degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNpc). Inflammation may be associated…”
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GSK-3 mediates the release of IL-1β, TNF-α and IL-10 from cortical glia
Published in Neurochemistry international (01-10-2012)“…Neuroinflammation has been shown to contribute to neurodegenerative and psychiatric disorders such as Alzheimer’s disease and major depression due to the…”
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Imaging of neurosphere oxygenation with phosphorescent probes
Published in Biomaterials (01-12-2013)“…Abstract Multicellular spheroids are useful models of mammalian tissue for studies of cell proliferation, differentiation, replacement therapies and drug…”
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Dietary Supplementation with a Magnesium-Rich Marine Mineral Blend Enhances the Diversity of Gastrointestinal Microbiota
Published in Marine drugs (20-06-2018)“…Accumulating evidence demonstrates that dietary supplementation with functional food ingredients play a role in systemic and brain health as well as in healthy…”
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The 'middle-aging' brain
Published in Trends in neurosciences (Regular ed.) (01-04-2024)“…Middle age (roughly the fifth and sixth decades of human life) has historically been understudied compared to more advanced age, but is emerging as marking a…”
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Motivation and learning methods of anatomy: Associations with mental well‐being
Published in Clinical anatomy (New York, N.Y.) (01-01-2022)“…Appropriate anatomy education for speech and language therapists is a crucial part of preparation for clinical practice. While much research has been conducted…”
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Plasma proteomic signature of chronic psychosocial stress in mice
Published in Physiology & behavior (10-11-2024)“…•Abundances of 38 plasma proteins were affected by chronic psychosocial stress in mice.•The proteins function in inflammatory & immune response, complement &…”
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Adolescent social isolation stress unmasks the combined effects of adolescent exercise and adult inflammation on hippocampal neurogenesis and behavior
Published in Neuroscience (04-12-2017)“…•Adolescent isolation stress resulted in decreased body weight, voluntary exercise, and percentage of surviving new neurons.•Chronic hippocampal IL-1β…”
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Intermittent fasting to slow down Alzheimer's disease
Published in Nature aging (01-11-2022)“…In our aging global population and with no effective treatments, the cognitive impairments associated with Alzheimer’s disease represent a major healthcare…”
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