Search Results - "Nolan, Andrea M"

Validity and Responsiveness of the Generic Health-Related Quality of Life Instrument (VetMetrica™) in Cats With Osteoarthritis. Comparison of Vet and Owner Impressions of Quality of Life Impact by Scott, E Marian, Davies, Vinny, Nolan, Andrea M, Noble, Cory E, Dowgray, Nathalie J, German, Alexander J, Wiseman-Orr, M Lesley, Reid, Jacqueline

“…Validity is not an inherent property of a measurement scale and so evidence for validity relating to its use for particular purposes, with defined populations…”
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Co-Induction of Cyclooxyenase-2 and Early Growth Response Gene (Egr-1) in Spinal Cord in a Clinical Model of Persistent Inflammation and Hyperalgesia by Dolan, Sharron, Hastie, Peter, Crossan, Claire, Nolan, Andrea M

“…Background: This study characterised the effects of persistent peripheral inflammation of the foot on pain and spinal cord expression of cyclooxygenase-1 and…”
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Pre-natal stress amplifies the immediate behavioural responses to acute pain in piglets by Rutherford, Kenneth M. D., Robson, Sheena K., Donald, Ramona D., Jarvis, Susan, Sandercock, Dale A., Scott, E. Marian, Nolan, Andrea M., Lawrence, Alistair B.

“…in utero…”
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Development, initial validation and reliability testing of a web-based, generic feline health-related quality-of-life instrument by Noble, Cory E, Wiseman-Orr, Lesley M, Scott, Marian E, Nolan, Andrea M, Reid, Jacky

“…Objectives The objective of this study was to develop a valid, reliable, web-based generic feline health-related quality-of-life (HRQoL) questionnaire…”
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Transient up-regulation of Spinal cyclooxygenase-2 and neuronal nitric oxide synthase following surgical inflammation by DOLAN, Sharron, KELLY, James G, HUAN, Marie, NOLAN, Andrea M

“…Surgery induces pain and hyperalgesia postoperatively. The products of cyclooxygenases and nitric oxide synthase (NOS) have been implicated in the development…”
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Expression of gonadotropin-releasing hormone and gonadotropin-releasing hormone receptor in sheep spinal cord by Dolan, Sharron, Evans, Neil P., Richter, Trevor A., Nolan, Andrea M.

“…Consistent with its neuroendocrine role, gonadotropin-releasing hormone (GnRH) is located principally within the hypothalamus, although extra-hypothalamic…”
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Validation of a structured questionnaire as an instrument to measure chronic pain in dogs on the basis of effects on health-related quality of life by Wiseman-Orr, M.L, Scott, E.M, Reid, J, Nolan, A.M

“…To validate the use of a novel questionnaire as an instrument for measurement of chronic pain in dogs through its impact on health-related quality of life…”
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The selective metabotropic glutamate receptor 7 allosteric agonist AMN082 inhibits inflammatory pain-induced and incision-induced hypersensitivity in rat by Dolan, Sharron, Gunn, Mark D, Biddlestone, Laura, Nolan, Andrea M

“…This study characterized the contribution of metabotropic glutamate receptor 7 (mGlu7 receptor) activation to the development of inflammatory hyperalgesia and…”
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Application of a scaling model to establish and validate an interval level pain scale for assessment of acute pain in dogs by Morton, C.M, Reid, J, Scott, E.M, Holton, L.L, Nolan, A.M

“…To establish interval level measurement in a prototype composite measure pain scale (CMPS) for assessment of acute pain in dogs and to investigate the scale's…”
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The impact of prenatal stress on basal nociception and evoked responses to tail-docking and inflammatory challenge in juvenile pigs by Sandercock, Dale A, Gibson, Ian F, Rutherford, Kenneth M.D, Donald, Ramona D, Lawrence, Alistair B, Brash, Harry M, Scott, E. Marian, Nolan, Andrea M

“…Abstract The consequences of tail-docking (at 2–4 days) and prenatal stress (maternal social stress during the 2nd third of pregnancy) on baseline nociceptive…”
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Development of a questionnaire to measure the effects of chronic pain on health-related quality of life in dogs by Wiseman-Orr, M.L, Nolan, A.M, Reid, J, Scott, E.M

“…To develop a reliable, validated questionnaire that can be used for the assessment of chronic pain and its impact on health-related quality of life (HRQL) in…”
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Differential protein composition of bovine whey: A comparison of whey from healthy animals and from those with clinical mastitis by Hogarth, Caroline J., Fitzpatrick, Julie L., Nolan, Andrea M., Young, Fiona J., Pitt, Andrew, Eckersall, P. David

“…During clinical mastitis in dairy cows, the quantity of milk produced decreases and the composition of the milk is altered. As the severity of inflammation…”
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Up-regulation of metabotropic glutamate receptor subtypes 3 and 5 in spinal cord in a clinical model of persistent inflammation and hyperalgesia by Dolan, Sharron, Kelly, James G, Monteiro, Ana M, Nolan, Andrea M

“…Evidence from experimental pain research has revealed that metabotropic glutamate receptors (mGluRs) play a pivotal role in nociceptive processing,…”
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Development of a mechanical stimulator and force measurement system for the assessment of nociceptive thresholds in pigs by Sandercock, Dale A., Gibson, Ian F., Brash, Harry M., Rutherford, Kenneth M.D., Scott, E. Marian, Nolan, Andrea M.

“…A mechanical stimulator and force measurement system was developed to quantify withdrawal thresholds to noxious mechanical stimulation of the foot in young…”
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Behavioural evidence supporting a differential role for group I and II metabotropic glutamate receptors in spinal nociceptive transmission by Dolan, Sharron, Nolan, Andrea M

“…Metabotropic glutamate receptors (mGluRs) have been shown to contribute to nociceptive processing in spinal cord. This study examined the effects of…”
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Biphasic modulation of nociceptive processing by the cyclic AMP-protein kinase A signalling pathway in sheep spinal cord by Dolan, Sharron, Nolan, Andrea M.

“…A role for the cyclic AMP (cAMP)-protein kinase A (PKA) transduction cascade in nociceptive processing has been identified. This study examined the effects of…”
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Differential expression of central metabotropic glutamate receptor (mGluR) subtypes in a clinical model of post-surgical pain by Dolan, Sharron, Kelly, James G, Monteiro, Ana M, Nolan, Andrea M

“…Tissue damage during surgery can induce ‘central sensitization’ and the development of pain and hyperalgesia post-operatively. Metabotropic glutamate receptors…”
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The role of nitric oxide and prostaglandin signaling pathways in spinal nociceptive processing in chronic inflammation by Dolan, Sharron, Field, Lois C, Nolan, Andrea M

“…Both nitric oxide (NO) and prostaglandins (PG) and their associated enzymes nitric oxide synthases (NOS) and cyclooxygenases (COX) (specifically COX-2) have…”
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N-methyl D-aspartate induced mechanical allodynia is blocked by nitric oxide synthase and cyclooxygenase-2 inhibitors by Dolan, Sharron, Nolan, Andrea M

“…THE role of spinal NMDA receptors in mechanical nociceptive processing was assessed in sheep. Intrathecal NMDA (2 nmol–1 μmol) produced a significant reduction…”
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Conceptual and methodological issues related to welfare assessment: A framework for measurement by Scott, E.M, Nolan, A.M, Fitzpatrick, J.L. (Glasgow Univ. (United Kingdom))

“…In all facets of animal welfare, as in human health and quality of life, the unambiguous and valid measurement of the key attributes is of critical importance…”
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