Search Results - "Nokhrin, Sergiy"
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Electron–phonon interaction in efficient perovskite blue emitters
Published in Nature materials (01-06-2018)“…Low-dimensional perovskites have—in view of their high radiative recombination rates—shown great promise in achieving high luminescence brightness and colour…”
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2
One-step amino acid selective isotope labeling of proteins in prototrophic Escherichia coli strains
Published in Analytical biochemistry (15-07-2012)“…Amino acid selective isotope labeling is a useful approach to simplification of nuclear magnetic resonance (NMR) spectra of large proteins. Cell-free protein…”
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Cellular copper levels determine the phenotype of the Arg⁸⁷⁵ variant of ATP7B/Wilson disease protein
Published in Proceedings of the National Academy of Sciences - PNAS (29-03-2011)“…In human disorders, the genotype-phenotype relationships are often complex and influenced by genetic and/or environmental factors. Wilson disease (WD) is a…”
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Magnetic resonance in systems with equivalent spin-1/2 nuclides. Part 2: Energy values and spin states
Published in Journal of magnetic resonance (1997) (01-07-2008)“…In an earlier paper (Part 1), featuring group-theoretical analysis, it was shown that the isotropic EPR spectra of free radical ( S = 1/2) species XL n, where…”
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5
Magnetic resonance in systems with equivalent spin-1/2 nuclides. Part 1
Published in Journal of magnetic resonance (1997) (01-06-2005)“…Electron paramagnetic resonance (EPR) spectra of S = 1/2 systems XL n with n equivalent nuclei having spin I = 1/2 have been simulated for microwave…”
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6
Cu(II) and dopamine bind to α‐synuclein and cause large conformational changes
Published in The FEBS journal (01-06-2014)“…α‐Synuclein (AS) is an intrinsically disordered protein that can misfold and aggregate to form Lewy bodies in dopaminergic neurons, a classic hallmark of…”
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The use of nanopore analysis for discovering drugs which bind to α-synuclein for treatment of Parkinson's disease
Published in European journal of medicinal chemistry (17-12-2014)“…A major feature of Parkinson's disease is the formation of Lewy bodies in dopaminergic neurons which consist of misfolded α-synuclein. The binding of natural…”
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The metal chaperone Atox1 regulates the activity of the human copper transporter ATP7B by modulating domain dynamics
Published in The Journal of biological chemistry (03-11-2017)“…The human transporter ATP7B delivers copper to the biosynthetic pathways and maintains copper homeostasis in the liver. Mutations in ATP7B cause the…”
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The Structure of Metal Binding Domain 1 of the Copper Transporter ATP7B Reveals Mechanism of a Singular Wilson Disease Mutation
Published in Scientific reports (12-01-2018)“…Copper-transporter ATP7B maintains copper homeostasis in the human cells and delivers copper to the biosynthetic pathways for incorporation into the newly…”
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10
Duplication of a Single Strand in a β‑Sheet Can Produce a New Switching Function in a Photosensory Protein
Published in Biochemistry (Easton) (17-07-2018)“…Duplication of a single β-strand that forms part of a β-sheet in photoactive yellow protein (PYP) was found to produce two approximately isoenergetic protein…”
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Interactions between Metal-binding Domains Modulate Intracellular Targeting of Cu(I)-ATPase ATP7B, as Revealed by Nanobody Binding
Published in The Journal of biological chemistry (21-11-2014)“…The biologically and clinically important membrane transporters are challenging proteins to study because of their low level of expression, multidomain…”
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12
Cu(II) and dopamine bind to [alpha]-synuclein and cause large conformational changes
Published in The FEBS journal (01-06-2014)“…[alpha]-Synuclein (AS) is an intrinsically disordered protein that can misfold and aggregate to form Lewy bodies in dopaminergic neurons, a classic hallmark of…”
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13
Copper chaperone Atox1 interacts with the metal-binding domain of Wilson's disease protein in cisplatin detoxification
Published in Biochemical journal (15-08-2013)“…Human copper transporters ATP7B (Wilson's disease protein) and ATP7A (Menkes' disease protein) have been implicated in tumour resistance to cisplatin, a widely…”
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14
Hydrothermal Synthesis of Open-Framework Borophosphates with Tunable Micropore Sizes, Crystal Morphologies, and Thermal Stabilities
Published in Crystal growth & design (05-08-2015)“…Thermal stabilities of zeolitic frameworks are important parameters for many applications. Two decades of research have produced only a very small number of…”
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15
Difference in Stability of the N-domain Underlies Distinct Intracellular Properties of the E1064A and H1069Q Mutants of Copper-transporting ATPase ATP7B
Published in The Journal of biological chemistry (06-05-2011)“…Wilson disease (WD) is a disorder of copper metabolism caused by mutations in the Cu-transporting ATPase ATP7B. WD is characterized by significant phenotypic…”
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Effect of charge, topology and orientation of the electric field on the interaction of peptides with the α-hemolysin pore
Published in Journal of peptide science (01-11-2011)“…Nanopore analysis is an emerging technique of structural biology which employs nanopores, such as the α‐hemolysin pore, as a biosensor. A voltage applied…”
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Cellular copper levels determine the phenotype of the Arg^sup 875^ variant of ATP7B/Wilson disease protein
Published in Proceedings of the National Academy of Sciences - PNAS (29-03-2011)“…In human disorders, the genotype-phenotype relationships are often complex and influenced by genetic and/or environmental factors. Wilson disease (WD) is a…”
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18
Cellular copper levels determine the phenotype of the Arg 875 variant of ATP7B/Wilson disease protein
Published in Proceedings of the National Academy of Sciences - PNAS (29-03-2011)“…In human disorders, the genotype-phenotype relationships are often complex and influenced by genetic and/or environmental factors. Wilson disease (WD) is a…”
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Cellular copper levels determine the phenotype of the Argâ¸â·âµ variant of ATP7B/Wilson disease protein
Published in Proceedings of the National Academy of Sciences - PNAS (2011)“…In human disorders, the genotype-phenotype relationships are often complex and influenced by genetic and/or environmental factors. Wilson disease (WD) is a…”
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20
Natural radiation-induced damage in quartz; II, Distribution and implications for uranium mineralization in the Athabasca Basin, Saskatchewan, Canada
Published in Canadian mineralogist (01-12-2006)“…The distribution of natural radiation-induced damage in quartz from the U-mineralized Athabasca Basin in northern Saskatchewan has been studied by CL and…”
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