Search Results - "Nojima, Hitomi"
-
1
Roles of IGFBP-3 in cell migration and growth in an endophytic tongue squamous cell carcinoma cell line
Published in Scientific reports (07-07-2022)“…Insulin-like growth factor binding protein-3 (IGFBP-3) is a member of the IGFBP family that has high affinity for IGFs and functions as either an oncogene or…”
Get full text
Journal Article -
2
MRI before biopsy correlates with depth of invasion corrected for shrinkage rate of the histopathological specimen in tongue carcinoma
Published in Scientific reports (25-10-2021)“…The purpose of this study was to evaluate which radiological depth of invasion (r-DOI) measurement is the most concordant to clinical DOI (c-DOI) derived from…”
Get full text
Journal Article -
3
Fluctuation in radioresponse of HeLa cells during the cell cycle evaluated based on micronucleus frequency
Published in Scientific reports (30-11-2020)“…In this study, we examined the fluctuation in radioresponse of HeLa cells during the cell cycle. For this purpose, we used HeLa cells expressing two types of…”
Get full text
Journal Article -
4
Differential properties of mitosis-associated events following CHK1 and WEE1 inhibitor treatments in human tongue carcinoma cells
Published in Experimental cell research (15-01-2020)“…CHK1 and WEE1 play pivotal roles in G2/M checkpoint following exogenous DNA damage and regulation of DNA replication under normal cellular conditions. Here, we…”
Get full text
Journal Article -
5
DNA damage response in a 2D-culture model by diffusing alpha-emitters radiation therapy (Alpha-DaRT)
Published in Scientific reports (20-05-2024)“…Diffusing alpha-emitters radiation therapy (Alpha-DaRT) is a unique method, in which interstitial sources carrying 224 Ra release a chain of short-lived…”
Get full text
Journal Article -
6
Induction of endomitosis-like event in HeLa cells following CHK1 inhibitor treatment
Published in Biochemical and biophysical research communications (03-12-2019)“…The effects of CHK1 inhibitor on cell cycle kinetics have not been fully investigated yet. In this study, we closely analyzed this kinetics using a CHK1…”
Get full text
Journal Article -
7
Retrograde Migration of an Au-198 Grain to the Submandibular Gland Post Brachytherapy Treatment of Floor of Mouth Cancer
Published in Curēus (Palo Alto, CA) (26-11-2022)“…At our institution, radiation oncologists routinely treat early-stage oral cancer with low-dose-rate brachytherapy (LDR-BRT) using Au-198 grains. In this…”
Get full text
Journal Article -
8
Estimating Impacts of p16 Status on Tumor Radiosensitivity in Head and Neck Cancer using Predictive Models
Published in Radiation research (01-09-2024)“…The intrinsic radiosensitivity index (RSI) and genomic-adjusted radiation dose (GARD) were reported to be able to predict the surviving fraction at 2 Gy and…”
Get full text
Journal Article -
9
Effect of Ablative Dose Irradiation on Redistribution and Radioresponse in a Mouse Xenograft Model
Published in Radiation research (01-12-2022)“…We investigated the effects of ablative dose irradiation on redistribution and radioresponse after the second irradiation in a mouse xenograft model, assuming…”
Get full text
Journal Article -
10
In vitro and in silico study of biological effects on cancer cells in the presence of metallic materials during radiotherapy
Published in Journal of radiation research (24-09-2024)“…Abstract X-ray therapy aims to eliminate tumours while minimizing side effects. Intense mucositis is sometimes induced when irradiating the oral cavity with a…”
Get full text
Journal Article -
11
Management of retropharyngeal lymph node metastasis in oral cancer
Published in Oral oncology (01-12-2019)“…•Retropharyngeal lymph node (RPLN) metastasis is extremely rare in oral cancer.•RPLN metastasis had poorer prognosis than cervical lymph node metastasis.•Early…”
Get full text
Journal Article -
12
Clinical investigation of use of Episil® oral solution in oral mucositis during radiotherapy for head and neck cancer
Published in Heliyon (01-06-2023)“…Episil® is a bio adhesive barrier-forming oral liquid gel that has been used in recent years to relieve pain of oral mucositis (OM) with radiotherapy (RT) or…”
Get full text
Journal Article -
13
Retrograde Migration of an Au-198 Grain to the Submandibular Gland Post Brachytherapy Treatment of Floor of Mouth Cancer
Published in Cureus (01-11-2022)Get full text
Report