Search Results - "Noh, Shin Hye"

Synergistic toxicity with copper contributes to NAT2-associated isoniazid toxicity by Yoon, Jihoon G., Jang, Dong Geon, Cho, Sung-Gyu, Lee, Chaeyoung, Noh, Shin Hye, Seo, Soo Kyung, Yu, Jung Woo, Chung, Hyeon Woo, Han, KyeoRe, Kwon, Soon Sung, Han, Dai Hoon, Oh, Jaeseong, Jang, In-Jin, Kim, Sang-Hoon, Jee, Young-Koo, Lee, Hyun, Park, Dong Won, Sohn, Jang Won, Yoon, Ho Joo, Kim, Chul Hoon, Lee, Jae Myun, Kim, Sang-Heon, Lee, Min Goo

“…Anti-tuberculosis (AT) medications, including isoniazid (INH), can cause drug-induced liver injury (DILI), but the underlying mechanism remains unclear. In…”
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Rescue of ΔF508-CFTR Trafficking via a GRASP-Dependent Unconventional Secretion Pathway by Gee, Heon Yung, Noh, Shin Hye, Tang, Bor Luen, Kim, Kyung Hwan, Lee, Min Goo

“…The most prevalent disease-causing mutation of CFTR is the deletion of Phe508 (ΔF508), which leads to defects in conventional Golgi-mediated exocytosis and…”
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Specific autophagy and ESCRT components participate in the unconventional secretion of CFTR by Noh, Shin Hye, Gee, Heon Yung, Kim, Yonjung, Piao, He, Kim, Jiyoon, Kang, Chung Min, Lee, Gahyung, Mook-Jung, Inhee, Lee, Yangsin, Cho, Jin Won, Lee, Min Goo

“…The most common mutation in cystic fibrosis patients is a phenylalanine deletion at position 508 (ΔF508) in the CFTR (cystic fibrosis transmembrane conductance…”
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Autophagy-Related Pathways in Vesicular Unconventional Protein Secretion by Noh, Shin Hye, Kim, Ye Jin, Lee, Min Goo

“…Cellular proteins directed to the plasma membrane or released into the extracellular space can undergo a number of different pathways. Whereas the molecular…”
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Monomerization and ER Relocalization of GRASP Is a Requisite for Unconventional Secretion of CFTR by Kim, Jiyoon, Noh, Shin Hye, Piao, He, Kim, Dong Hee, Kim, Kuglae, Cha, Jeong Seok, Chung, Woo Young, Cho, Hyun‐Soo, Kim, Joo Young, Lee, Min Goo

“…Endoplasmic reticulum (ER)‐to‐Golgi blockade or ER stress induces Golgi reassembly stacking protein (GRASP)‐mediated, Golgi‐bypassing cell‐surface trafficking…”
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ZMYND10 stabilizes intermediate chain proteins in the cytoplasmic pre-assembly of dynein arms by Cho, Kyeong Jee, Noh, Shin Hye, Han, Soo Min, Choi, Won-Il, Kim, Hye-Youn, Yu, Seyoung, Lee, Joon Suk, Rim, John Hoon, Lee, Min Goo, Hildebrandt, Friedhelm, Gee, Heon Yung

“…Zinc finger MYND-type-containing 10 (ZMYND10), a cytoplasmic protein expressed in ciliated cells, causes primary ciliary dyskinesia (PCD) when mutated;…”
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Novel small molecule-mediated restoration of the surface expression and anion exchange activity of mutated pendrin causing Pendred syndrome and DFNB4 by Jung, Jinsei, Noh, Shin Hye, Jo, Sungwoo, Song, Doona, Kang, Min Jin, Shin, Mi Hwa, Lee, Hyun Jae, Pyun, Jae-Chul, Namkung, Wan, Han, Gyoonhee, Lee, Min Goo, Choi, Jae Young

“…Variants in SLC26A4 (pendrin) are the most common reasons for genetic hearing loss and vestibular dysfunction in East Asians. In patients with Pendred syndrome…”
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Sec16A is critical for both conventional and unconventional secretion of CFTR by Piao, He, Kim, Jiyoon, Noh, Shin Hye, Kweon, Hee-Seok, Kim, Joo Young, Lee, Min Goo

“…CFTR is a transmembrane protein that reaches the cell surface via the conventional Golgi mediated secretion pathway. Interestingly, ER-to-Golgi blockade or ER…”
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Amelioration of SARS-CoV-2 infection by ANO6 phospholipid scramblase inhibition by Sim, Ju-Ri, Shin, Dong Hoon, Park, Pil-Gu, Park, So-Hyeon, Bae, Joon-Yong, Lee, Youngchae, Kang, Dha-Yei, Kim, Ye Jin, Aum, Sowon, Noh, Shin Hye, Hwang, Su Jin, Cha, Hye-Ran, Kim, Cheong Bi, Ko, Si Hwan, Park, Sunghoon, Jeon, Dongkyu, Cho, Sungwoo, Lee, Gee Eun, Kim, Jeonghun, Moon, Young-hye, Kim, Jae-Ouk, Nam, Jae-Sung, Kim, Chang-Hoon, Moon, Sungmin, Chung, Youn Wook, Park, Man-Seong, Ryu, Ji-Hwan, Namkung, Wan, Lee, Jae Myun, Lee, Min Goo

“…As an enveloped virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) delivers its viral genome into host cells via fusion of the viral and cell…”
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Grasp55−/− mice display impaired fat absorption and resistance to high-fat diet-induced obesity by Kim, Jiyoon, Kim, Hyeyon, Noh, Shin Hye, Jang, Dong Geon, Park, Shi-Young, Min, Dongkook, Kim, Hyunki, Kweon, Hee-Seok, Kim, Hoguen, Aum, Sowon, Seo, Sookyung, Choi, Cheol Soo, Kim, Hail, Kim, Jae Woo, Moon, Seok Jun, Gee, Heon Yung, Lee, Min Goo

“…The Golgi apparatus plays a central role in the intracellular transport of macromolecules. However, molecular mechanisms of Golgi-mediated lipid transport…”
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TMED3 Complex Mediates ER Stress‐Associated Secretion of CFTR, Pendrin, and SARS‐CoV‐2 Spike by Park, Hak, Seo, Soo Kyung, Sim, Ju‐Ri, Hwang, Su Jin, Kim, Ye Jin, Shin, Dong Hoon, Jang, Dong Geon, Noh, Shin Hye, Park, Pil‐Gu, Ko, Si Hwan, Shin, Mi Hwa, Choi, Jae Young, Ito, Yukishige, Kang, Chung‐Min, Lee, Jae Myun, Lee, Min Goo

“…Under ER stress conditions, the ER form of transmembrane proteins can reach the plasma membrane via a Golgi‐independent unconventional protein secretion (UPS)…”
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Specific kinesin and dynein molecules participate in the unconventional protein secretion of transmembrane proteins by Eun, Sung Ho, Noh, Shin Hye, Lee, Min Goo

“…Secretory proteins, including plasma membrane proteins, are generally known to be transported to the plasma membrane through the endoplasmic reticulum-…”
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Functional characterization of ABCB4 mutations found in progressive familial intrahepatic cholestasis type 3 by Park, Hyo Jin, Kim, Tae Hee, Kim, So Won, Noh, Shin Hye, Cho, Kyeong Jee, Choi, Choe, Kwon, Eun Young, Choi, Yang Ji, Gee, Heon Yung, Choi, Ji Ha

“…Multidrug resistance 3 (MDR3), encoded by the ATP-binding cassette, subfamily B, member 4 gene ( ABCB4 ), localizes to the canalicular membrane of hepatocytes…”
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Multicenter Surveillance of Cystic Fibrosis in Korean Children by Kim, Hyung Young, Hong, Soo-Jong, Ahn, Kangmo, Suh, Dong In, Noh, Shin Hye, Kim, Soo Yeon, Yu, Jinho, Ko, Jung Min, Lee, Min Goo, Kim, Kyung Won

“…Purpose Cystic fibrosis (CF), caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, is rare among non-Caucasians. We…”
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Autophagosome-mediated unconventional trafficking of CFTR by Noh, Shin Hye, Gee, Heon Yung, Lee, Min Goo

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Shank2 mutant mice display a hypersecretory response to cholera toxin by Jung, Eun Suk, Park, Joonhee, Gee, Heon Yung, Jung, Jinsei, Noh, Shin Hye, Lee, Jung‐Soo, Richter, Wito, Namkung, Wan, Lee, Min Goo

“…Key points Among the three Shank proteins in human (Shank1–3), Shank2 is abundantly expressed in epithelial cells. However, the in vivo physiological role of…”
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